Differences in the thermal bioclimatic conditions on the urban and rural areas in a southern Hungarian city (Szeged)

The aim of this study is to compare the bioclimatic situation of a city and the surrounding rural area on the example of a Southern Hungarian city (Szeged). To examine the frequency of the one hour averages of the PET index, it is shown that due to the strong direct radiation a strong or extreme heat stress values has 1.1 % higher occurrence in the rural areas compared to the urban ones. But considering the PET averages through the whole examined time period, it is 14 % higher in the urban areas. This effect is more pronounced in summer, when daytime with extreme heat stress is followed by night with 7-8 °C higher PET values in the city. During these times, the human body cannot regenerate in the nights before the repeated extreme heat stress occurs again during daytime. This makes the urban bioclimatic conditions (in summer, especially during heat wave) more demanding, compared to the rural ones

Electrophysiological, biochemical, and bioinformatic methods for studying CFTR channel gating and its regulation.

CFTR is the only member of the ABC (ATP-binding cassette) protein superfamily known to function as an ion channel. Most other ABC proteins are ATP-driven transporters, in which a cycle of ATP binding and hydrolysis, at intracellular nucleotide binding domains (NBDs), powers uphill substrate translocation across the membrane. In CFTR, this same ATP-driven cycle opens and closes a transmembrane pore through which chloride ions flow rapidly down their electrochemical gradient. Detailed analysis of the pattern of gating of CFTR channels thus offers the opportunity to learn about mechanisms of function not only of CFTR channels but also of their ABC transporter ancestors. In addition, CFTR channel gating is subject to complex regulation by kinase-mediated phosphorylation at multiple consensus sites in a cytoplasmic regulatory domain that is unique to CFTR. Here we offer a practical guide to extract useful information about the mechanisms that control opening and closing of CFTR channels: on how to plan (including information obtained from analysis of multiple sequence alignments), carry out, and analyze electrophysiological and biochemical experiments, as well as on how to circumvent potential pitfalls

e+e−e^{+}e^{-} pairs from a nuclear transition signaling an elusive light neutral boson

Electron-positron pairs have been observed in the 10.95-MeV $0^-\to0^+$ decay in $^{16}$O. The branching ratio of the e$^+$e$^-$ pairs compared to the 3.84-MeV $0^-\to2^+$ $\gamma$ decay of the level is deduced to be $20(5)\times10^{-5}$. This magnetic monopole (M0) transition cannot proceed by $\gamma$-ray decay and is, to first order, forbidden for internal pair creation. However, the transition may also proceed by the emission of a light neutral $0^{-}$ or $1^{+}$ boson. Indeed, we do observe a sharp peak in the $e^{+}e^{-}$ angular correlation with all the characteristics belonging to the intermediate emission of such a boson with an invariant mass of 8.5(5) MeV/c$^2$. It may play a role in the current quest for light dark matter in the universe.Comment: 6 page

mRNA transcription profile of potato (Solanum tuberosum L.) exposed to ultrasound during different stages of in vitro plantlet development

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Observation of Anomalous Internal Pair Creation in 8^8Be: A Possible Signature of a Light, Neutral Boson

Electron-positron angular correlations were measured for the isovector magnetic dipole 17.6 MeV state ($J^\pi=1^+$, $T=1$) $\rightarrow$ ground state ($J^\pi=0^+$, $T=0$) and the isoscalar magnetic dipole 18.15 MeV ($J^\pi=1^+$, $T=0$) state $\rightarrow$ ground state transitions in $^{8}$Be. Significant deviation from the internal pair creation was observed at large angles in the angular correlation for the isoscalar transition with a confidence level of $> 5\sigma$. This observation might indicate that, in an intermediate step, a neutral isoscalar particle with a mass of 16.70$\pm0.35$ (stat)$\pm 0.5$ (sys) MeV$/c^2$ and $J^\pi = 1^+$ was created.Comment: 5 pages, 5 figure

Transmission resonance spectroscopy in the third minimum of 232Pa

The fission probability of 232Pa was measured as a function of the excitation energy in order to search for hyperdeformed (HD) transmission resonances using the (d,pf) transfer reaction on a radioactive 231Pa target. The experiment was performed at the Tandem accelerator of the Maier-Leibnitz Laboratory (MLL) at Garching using the 231Pa(d,pf) reaction at a bombarding energy of E=12 MeV and with an energy resolution of dE=5.5 keV. Two groups of transmission resonances have been observed at excitation energies of E=5.7 and 5.9 MeV. The fine structure of the resonance group at E=5.7 MeV could be interpreted as overlapping rotational bands with a rotational parameter characteristic to a HD nuclear shape. The fission barrier parameters of 232Pa have been determined by fitting TALYS 1.2 nuclear reaction code calculations to the overall structure of the fission probability. From the average level spacing of the J=4 states, the excitation energy of the ground state of the 3rd minimum has been deduced to be E(III)=5.05 MeV.Comment: 6 pages, 8 figure

Exploring the multi-humped fission barrier of 238U via sub-barrier photofission

The photofission cross-section of 238U was measured at sub-barrier energies as a function of the gamma-ray energy using, for the first time, a monochromatic, high-brilliance, Compton-backscattered gamma-ray beam. The experiment was performed at the High Intensity gamma-ray Source (HIgS) facility at beam energies between E=4.7 MeV and 6.0 MeV and with ~3% energy resolution. Indications of transmission resonances have been observed at gamma-ray beam energies of E=5.1 MeV and 5.6 MeV with moderate amplitudes. The triple-humped fission barrier parameters of 238U have been determined by fitting EMPIRE-3.1 nuclear reaction code calculations to the experimental photofission cross section.Comment: 5 pages, 3 figure