9 research outputs found

    A Survey of Public Perception of CCUS in China

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    AbstractA high public acceptance is viewed as one of critical factors for a success of a new technology. To date, there are very few systematic researches into public communication and engagement in regard to CCUS in China. A national survey on public perception of CCUS technology was conducted to serve five research objectives: public understanding of climate sciences; society's knowledge of low emission technologies (especially of CCUS technology); the public interests and concerns about positive and negative impacts of CCS technology; public attitudes towards CCUS policies supported by government

    Synthesis and biological evaluation of novel hydrogen sulfide releasing glycyrrhetic acid derivatives

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    <p>A series of hybrids, which are composed of glycyrrhetic acid (GA) and slowly hydrogen sulfide-releasing donor ADT-OH, were designed and synthesized to develop anticancer and anti-inflammatory agents. Most of the compounds, whose inhibitory rates were comparable to or higher than those of GA and aspirin, respectively, significantly inhibited xylene-induced ear edema in mice. Especially, compound V<b><sub>4</sub></b>exhibited the most potent inhibitory rate of 60.7%. Furthermore, preliminary structure–activity relationship studies demonstrated that 3-substituted GA derivatives had stronger anti-inflammatory activities than the corresponding 3-unsubstituted GA derivatives. In addition, anti-proliferative activities of compounds <b>V<sub>1−9</sub></b> were evaluated in three different human cancer cell lines. Compound <b>V<sub>4</sub></b> showed the most high potency against all three tumor cell lines with IC<sub>50</sub> values ranging from 10.01 μM in Hep G2 cells to 17.8 μM in MDA-MB-231 cells, which were superior to positive GA.</p
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