180 research outputs found

    A cor do meu silêncio: ebano em lilás

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    Este trabalho propõe uma reflexão sobre a interação da linguagem da dança e o pensamento sobre corpo que esta enaltece, com a investigação da memória corporal sem três aspectos: O vazio, o silêncio e a poética gestual. Trata-se do corpo como morada, caminho e veiculo de comunicação entre a dança e as questões relevantes a seus pares; dança como possibilidade de experimentar as sensações trazidas pelo esgotamento do corpo que ao se esconder de si mesmo, encontra-se com seus próprios mitos silenciados, pois quando o corpo habita o silêncio, o gesto se torna essência ontológica ao desvelar a dança como substância poética da linguagem do indizível. Existe algo além da superfície... Algum lugar entre o coração e nossa miscigenação, que nossas histórias não garantem revelação, mas que a poesia e a subjetividade permitem ao menos uma porta entreaberta para argumentos e experimentações -- o risco -- suficiente para criação. Com isso, pretende-se pesquisar estudar e refletir sobre a elaboração coreográfica e suas contribuições para a discussão a cerca do argumento de que o corpo-dança é em si movimento e pensamento, linguagem do indizível.Palavras-chave: Dança, linguagem e silêncio

    Measuring valley polarization in two-dimensional materials with second-harmonic spectroscopy

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    A population imbalance at different valleys of an electronic system lowers its effective rotational symmetry. We introduce a technique to measure such imbalance - a valley polarization - that exploits the unique fingerprints of this symmetry reduction in the polarization-dependent second-harmonic generation (SHG). We present the principle and detection scheme in the context of hexagonal two-dimensional crystals, which include graphene-based systems and the family of transition metal dichalcogenides, and provide a direct experimental demonstration using a 2H-MoSe2_{2} monolayer at room temperature. We deliberately use the simplest possible setup, where a single pulsed laser beam simultaneously controls the valley imbalance and tracks the SHG process. We further developed a model of the transient population dynamics which analytically describes the valley-induced SHG rotation in very good agreement with the experiment. In addition to providing the first experimental demonstration of the effect, this work establishes a conceptually simple, com-pact and transferable way of measuring instantaneous valley polarization, with direct applicability in the nascent field of valleytronics

    Association between the -420 C> G polymorphism (rs1862513) in the human resistin gene and obesity in a sample of the Brazilian population / Associação entre o polimorfismo -420 C>G (rs1862513) no gene da resistina humana e obesidade em uma amostra da população brasileira

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    Purpose: Obesity became a serious public health problem in the last decades and is associated with several comorbidities such as type 2 diabetes, cardiovascular diseases, and some types of cancer. Adipose tissue cells produce various proinflammatory cytokines including resistin (RETN). Several studies have shown that RETN polymorphisms may be potentially related to the predisposition to obesity, but the results are contradictory. Herein we aimed to investigate the frequency of the RETN -420 C>G (rs1862513) polymorphism and its association with obesity in a sample of adults of both sexes residing in the city of Jataí - GO, Brazil. Subjects and Methods: This cross-sectional study was conducted with 117 participants from which 72 were genotyped for RETN polymorphism. Anthropometric measurements such as body mass index (BMI) and waist circumference (WC) were obtained and used to classify individuals in eutrophic, overweight and obese. Systolic and diastolic blood pressure (SBP and DBP) were measured and lipidic and fasting blood glucose profiles were determined. Polymorphisms were determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Results: There was no statistical difference between the RETN -420 C >G polymorphism and the variables BMI and lipidic profile. However, there was a significant difference in the frequency of  C/C genotype in the group with WC values associated with high risk of cardiovascular disease compared to the lower risk group both in the codominant model (C/C; C/G, G/G) and in the dominant genetic model (C/C, C/G + G/G).Conclusion: RETN -420 C >G polymorphism is not associated with obesity in the sample of Brazilian population analyzed in this study, however the RETN C/C genotype may be associated with cardiovascular risk and deserves further investigation

    A educação ambiental nas aulas de química do Ensino Superior : resultados de uma investigação realizada em uma universidade pública brasileira

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    O presente trabalho aponta resultados de uma pesquisa que investigou as concepções dos docentes e dos técnicos de laboratórios de ensino de química, de uma universidade pública brasileira, sobre as atividades e ações desenvolvidas para contemplar a Resolução Brasileira (02/2012). A referida Resolução determina que a Educação Ambiental deve ser integrante do currículo dos cursos das Instituições de Ensino Superior brasileiras para formação crítica dos estudantes sobre as questões socioambientais. A análise dos resultados evidenciou que a Educação Ambiental ainda é abordada de forma naturalista, distanciada da abordagem política e social, como propõem nos documentos oficiais que orientam a educação brasileira no nível superior

    Inovação na indústria de alimentos: importância e dinâmica no complexo agroindustrial brasileiro

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    Bibliografia: p. 366-370Estudo que se fundamentou no modelo de Pavitt (1984) para entender a dinâmica da inovação no complexo agroindustrial, com foco na indústria de alimentos

    Mapping the lignin distribution in pretreated sugarcane bagasse by confocal and fluorescence lifetime imaging microscopy

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    Abstract\ud \ud \ud \ud Background\ud \ud Delignification pretreatments of biomass and methods to assess their efficacy are crucial for biomass-to-biofuels research and technology. Here, we applied confocal and fluorescence lifetime imaging microscopy (FLIM) using one- and two-photon excitation to map the lignin distribution within bagasse fibers pretreated with acid and alkali. The evaluated spectra and decay times are correlated with previously calculated lignin fractions. We have also investigated the influence of the pretreatment on the lignin distribution in the cell wall by analyzing the changes in the fluorescence characteristics using two-photon excitation. Eucalyptus fibers were also analyzed for comparison.\ud \ud \ud \ud Results\ud \ud Fluorescence spectra and variations of the decay time correlate well with the delignification yield and the lignin distribution. The decay dependences are considered two-exponential, one with a rapid (τ1) and the other with a slow (τ2) decay time. The fastest decay is associated to concentrated lignin in the bagasse and has a low sensitivity to the treatment. The fluorescence decay time became longer with the increase of the alkali concentration used in the treatment, which corresponds to lignin emission in a less concentrated environment. In addition, the two-photon fluorescence spectrum is very sensitive to lignin content and accumulation in the cell wall, broadening with the acid pretreatment and narrowing with the alkali one. Heterogeneity of the pretreated cell wall was observed.\ud \ud \ud \ud Conclusions\ud \ud Our results reveal lignin domains with different concentration levels. The acid pretreatment caused a disorder in the arrangement of lignin and its accumulation in the external border of the cell wall. The alkali pretreatment efficiently removed lignin from the middle of the bagasse fibers, but was less effective in its removal from their surfaces. Our results evidenced a strong correlation between the decay times of the lignin fluorescence and its distribution within the cell wall. A new variety of lignin fluorescence states were accessed by two-photon excitation, which allowed an even broader, but complementary, optical characterization of lignocellulosic materials. These results suggest that the lignin arrangement in untreated bagasse fiber is based on a well-organized nanoenvironment that favors a very low level of interaction between the molecules.The authors are grateful to FAPESP and CNPq for financial support and to the company QuantumTech for the technical support

    Effect of the spacing on rubber root-stock growth

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    O trabalho foi conduzido com o objetivo de se determinar, para as condições edafoclimáticas de Manaus, qual espaçamento entre plantas seria mais viável técnica e economicamente para a produção de porta-enxertos de seringueira (Hevea sp.). Foram testados doze tratamentos, constituídos por doze diferentes arranjos de espaçamentos entre linhas e entre plantas nas linhas. Constatou-se que, para a produção de mudas de seringueira do tipo toco-enxerto de raiz nua, empregando o método de enxertia verde, o melhor espaçamento de viveiro para a produção dos porta-enxertos, técnica e economicamente, é o de 60 cm x 15 cm. E para a produção do mesmo tipo de muda, empregando o método de enxertia convencional, o melhor espaçamento é ode 70 cm x 15 cm, seguido pelo de 60 cm x 15 cm.The objective of the present study was to determine, technically and economically, what spacing among plants would be better to grow rubber (Hevea sp.) root-stock, in the climate and soil conditions of Manaus, AM, Brazil, Twelve treatments constituted by twelve different arrangements of spacing among rows and among plants in the field were tested. It was proved that the 60 cm x 15cm spacing is the best for producing rubber budded-stump using green budding, while the 70 cm x 15 cm spacing is the best for producing budded-stump using brown-budding, followed by the 60cm x 15cm

    Mapping the lignin distribution in pretreated sugarcane bagasse by confocal and fluorescence lifetime imaging microscopy

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    Background: Delignification pretreatments of biomass and methods to assess their efficacy are crucial for biomassto- biofuels research and technology. Here, we applied confocal and fluorescence lifetime imaging microscopy (FLIM) using one- and two-photon excitation to map the lignin distribution within bagasse fibers pretreated with acid and alkali. The evaluated spectra and decay times are correlated with previously calculated lignin fractions. We have also investigated the influence of the pretreatment on the lignin distribution in the cell wall by analyzing the changes in the fluorescence characteristics using two-photon excitation. Eucalyptus fibers were also analyzed for comparison. Results: Fluorescence spectra and variations of the decay time correlate well with the delignification yield and the lignin distribution. The decay dependences are considered two-exponential, one with a rapid (τ1) and the other with a slow (τ2) decay time. The fastest decay is associated to concentrated lignin in the bagasse and has a low sensitivity to the treatment. The fluorescence decay time became longer with the increase of the alkali concentration used in the treatment, which corresponds to lignin emission in a less concentrated environment. In addition, the two-photon fluorescence spectrum is very sensitive to lignin content and accumulation in the cell wall, broadening with the acid pretreatment and narrowing with the alkali one. Heterogeneity of the pretreated cell wall was observed. Conclusions: Our results reveal lignin domains with different concentration levels. The acid pretreatment caused a disorder in the arrangement of lignin and its accumulation in the external border of the cell wall. The alkali pretreatment efficiently removed lignin from the middle of the bagasse fibers, but was less effective in its removal from their surfaces. Our results evidenced a strong correlation between the decay times of the lignin fluorescence and its distribution within the cell wall. A new variety of lignin fluorescence states were accessed by two-photon excitation, which allowed an even broader, but complementary, optical characterization of lignocellulosic materials. These results suggest that the lignin arrangement in untreated bagasse fiber is based on a well-organized nanoenvironment that favors a very low level of interaction between the molecules.FAPESPCNP

    Diabetes Mellitus Tipo 2 - aspectos epidemiológicos, fisiopatológicos e manejo terapêutico

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    O diabetes mellitus tipo 2 (DM2) é uma síndrome metabólica global em ascensão, caracterizada por resistência à insulina e níveis elevados de glicose no sangue. Quanto à epidemiologia, é um problema de saúde pública em rápido crescimento, com prevalência estimada de 90-95% dos pacientes diabéticos. Estimativas da Organização Mundial da Saúde (OMS) preveem que 693 milhões de adultos vivendo com a patologia até 2045. Sua prevalência é maior em pessoas do sexo masculino, mais suscetivel em etinia asiática e predominante na população urbana. Quanto à fisiopatologia, DM é um distúrbio metabólico caracterizado por hiperglicemia crônica, que pode levar a complicações agudas e crônicas. Os tipos mais comuns são Diabetes Mellitus Tipo 1 (DM1), o Diabetes Mellitus Tipo 2 (DM2) e o Diabetes Mellitus Gestacional (DMG). Quanto às manifestações clínicas, os pacientes portadores de DM2 frequentemente não apresentam sintomas na fase inicial, o que dificulta o diagnóstico precoce. Quando presente, os sintomas da DM2 incluem poliúria, polidipsia, polifagia, formigamento e perda de peso não intencional. Estes sintomas também estão presentes na DM1. Sua identificação depende de uma anamnese minuciosa, um exame físico bem detalhado e exames complementares. Para diagnóstico definitivo, lança-se mão da glicemia plasmática de jejum, teste oral de tolerância à glicose (TOTG), hemoglobina glicada (A1c) e glicemia ao acaso, fornecendo mais detalhes com melhor acurácia para, juntamente com os dados clínicos, obter o diagnóstico. Já a abordagem terapêutica, apresenta-se através do manejo farmacológico e mudança de hábitos e estilo de vida. Existem quatro grupos principais de medicamentos antidiabéticos: biguanidas, secretagogos de insulina, sensibilizadores de insulina e insulina ou seus análogos que vão atuar com mecanismos diferentes para controlar o diabetes

    LARGE NEUROENDOCRINE TUMOR IN A PATIENT WITH ACROMEGALY CASE REPORT.

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    The case of a patient with a rare malignancy whose incidence ranges from 0.2 to 2 / 100,000 individuals. The increase in incidence probably showed increasing changes in diagnosis. Approximately 25% of these tumors grow in the lungs and represent 2% of all lung tumors. Of all bronchial NETs, only 5% are associated with multiple type 1 endocrine neoplasms (MEN-1). According to the current WHO classification of 2015, neuroendocrine lung cancer should be classified into typical carcinoids, atypical carcinoids, large cell neuroendocrine carcinoma or small cell carcinoma, the classification being based on histological morphology. The commonly associated endocrine syndromes are inadequate secretion of the natriuretic hormone, Cushing's syndrome and, rarely, acromegaly. We report a case of a male patient with a large neuroendocrine tumor associated with a pituitary macroadenoma. Laboratory tests on admission were changed, GH of 56.5 ng / mL (Ref <5 ng / mL), IGF-1 of 1304.4 ng / mL (Ref-96.4 - 227.8 ng / mL), chromogranin 4.89 (Ref 3.00), b-HCG-negative. The patient was initially submitted to thoracic surgery and subsequently underwent neurological surgery in another center, so that he was accompanied by professionals from various areas, making it increasingly evident the need for hospitals to have centers for the study of these neuroendocrine tumors.The case of a patient with a rare malignancy whose incidence ranges from 0.2 to 2 / 100,000 individuals. The increase in incidence probably showed increasing changes in diagnosis. Approximately 25% of these tumors grow in the lungs and represent 2% of all lung tumors. Of all bronchial NETs, only 5% are associated with multiple type 1 endocrine neoplasms (MEN-1). According to the current WHO classification of 2015, neuroendocrine lung cancer should be classified into typical carcinoids, atypical carcinoids, large cell neuroendocrine carcinoma or small cell carcinoma, the classification being based on histological morphology. The commonly associated endocrine syndromes are inadequate secretion of the natriuretic hormone, Cushing's syndrome and, rarely, acromegaly. We report a case of a male patient with a large neuroendocrine tumor associated with a pituitary macroadenoma. Laboratory tests on admission were changed, GH of 56.5 ng / mL (Ref <5 ng / mL), IGF-1 of 1304.4 ng / mL (Ref-96.4 - 227.8 ng / mL), chromogranin 4.89 (Ref 3.00), b-HCG-negative. The patient was initially submitted to thoracic surgery and subsequently underwent neurological surgery in another center, so that he was accompanied by professionals from various areas, making it increasingly evident the need for hospitals to have centers for the study of these neuroendocrine tumors
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