New Preshower detector for DIRAC Experiment

The Preshower (PSh) detector is a component of the DIRAC setup. It is designed to improve rejection efficiency of e-e+ pairs background in the {\pi}{\pi} and K{\pi} pair measurement. To increase the overall efficiency, a new two-layer structure scintillator Preshower detector has been realized in the region where the Nitrogen Cherenkov detector has been shortened to introduce new detectors. The new Preshower-Cherenkov combination ensures the electron rejection efficiency better than 99.9% in momentum region 1-7 GeV/c.Comment: to be published in NIM

High-quality chronic care delivery improves experiences of chronically ill patients receiving care

__Abstract__ Objective. Investigate whether high-quality chronic care delivery improved the experiences of patients. Design. This study had a longitudinal design. Setting and Participants. We surveyed professionals and patients in 17 disease management programs targeting patients with cardiovascular diseases, chronic obstructive pulmonary disease, heart failure, stroke, comorbidity and eatin

Experimental investigation of the effect of ionization on the 51V(p,n)51Cr reaction

The investigation of the effects of average atomic ionization on nuclear reactions is of prime importance for nuclear astrophysics. No direct experimental measurement using a plasma target has been done yet. In this regard, we measured for the first time the neutron production of a (p,n) reaction in different states of ionization. The studied nuclear reaction was 51V(p,n)51Cr. We measured a significantly lower neutron production than expected when the target was ionized, even when taking into account existing electron screening theory or the effect of the stopping power in the target on the injected proton beam. This experiment is a first step in the process to characterize the influence of ionization at astrophysically relevant energies.Comment: 20 pages, 10 figures, submitted to EP

First πK\pi K atom lifetime and πK\pi K scattering length measurements

The results of a search for hydrogen-like atoms consisting of $\pi^{\mp}K^{\pm}$ mesons are presented. Evidence for $\pi K$ atom production by 24 GeV/c protons from CERN PS interacting with a nickel target has been seen in terms of characteristic $\pi K$ pairs from their breakup in the same target ($178 \pm 49$) and from Coulomb final state interaction ($653 \pm 42$). Using these results the analysis yields a first value for the $\pi K$ atom lifetime of $\tau=(2.5_{-1.8}^{+3.0})$ fs and a first model-independent measurement of the S-wave isospin-odd $\pi K$ scattering length $\left|a_0^-\right|=\frac{1}{3}\left|a_{1/2}-a_{3/2}\right|= \left(0.11_{-0.04}^{+0.09} \right)M_{\pi}^{-1}$ ($a_I$ for isospin $I$).Comment: 14 pages, 8 figure

X-ray fluorescence from the element with atomic number Z = 120

Accepted for publication in Physical Review LettersAn atomic clock based on X-ray fluorescence yields has been used to estimate the mean characteristic time for fusion followed by fission in reactions 238U + 64Ni at 6.6 MeV/A. Inner shell vacancies are created during the collisions in the electronic structure of the possibly formed Z=120 compound nuclei. The filling of these vacancies accompanied by X-ray emission with energies characteristic of Z=120 can take place only if the atomic transitions occur before nuclear fission. Therefore, the X-ray yield characteristic of the united atom with 120 protons is strongly related to the fission time and to the vacancy lifetimes. K X-rays from the element with Z = 120 have been unambiguously identified from a coupled analysis of the involved nuclear reaction mechanisms and of the measured photon spectra. A minimum mean fission time $\tau$_f$ = 2.5×10−18s has been deduced for Z=120 from the measured X-ray multiplicity

Determination of ππ\pi\pi scattering lengths from measurement of π+π−\pi^+\pi^- atom lifetime

The DIRAC experiment at CERN has achieved a sizeable production of $\pi^+\pi^-$ atoms and has significantly improved the precision on its lifetime determination. From a sample of 21227 atomic pairs, a 4% measurement of the S-wave $\pi\pi$ scattering length difference $|a_0-a_2| = (.0.2533^{+0.0080}_{-0.0078}|_\mathrm{stat}.{}^{+0.0078}_{-0.0073}|_\mathrm{syst})M_{\pi^+}^{-1}$ has been attained, providing an important test of Chiral Perturbation Theory.Comment: 6 pages, 6 figure

Investigation of K+K−K^+K^- pairs in the effective mass region near 2mK2m_K

The DIRAC experiment at CERN investigated in the reaction $\rm{p}(24~\rm{GeV}/c) + Ni$ the particle pairs $K^+K^-, \pi^+ \pi^-$ and $p \bar{p}$ with relative momentum $Q$ in the pair system less than 100 MeV/c. Because of background influence studies, DIRAC explored three subsamples of $K^+K^-$ pairs, obtained by subtracting -- using time-of-flight (TOF) technique -- background from initial $Q$ distributions with $K^+K^-$ sample fractions more than 70\%, 50\% and 30\%. The corresponding pair distributions in $Q$ and in its longitudinal projection $Q_L$ were analyzed first in a Coulomb model, which takes into account only Coulomb final state interaction (FSI) and assuming point-like pair production. This Coulomb model analysis leads to a $K^+K^-$ yield increase of about four at $Q_L=0.5$ MeV/c compared to 100 MeV/c. In order to study contributions from strong interaction, a second more sophisticated model was applied, considering besides Coulomb FSI also strong FSI via the resonances $f_0(980)$ and $a_0(980)$ and a variable distance $r^*$ between the produced $K$ mesons. This analysis was based on three different parameter sets for the pair production. For the 70\% subsample and with best parameters, $3680\pm 370$ $K^+K^-$ pairs was found to be compared to $3900\pm 410$ $K^+K^-$ extracted by means of the Coulomb model. Knowing the efficiency of the TOF cut for background suppression, the total number of detected $K^+K^-$ pairs was evaluated to be around $40000\pm 10\%$, which agrees with the result from the 30\% subsample. The $K^+K^-$ pair number in the 50\% subsample differs from the two other values by about three standard deviations, confirming -- as discussed in the paper -- that experimental data in this subsample is less reliable

Evidence for πK\pi K-atoms with DIRAC

We present evidence for the first observation of electromagnetically bound $\pi^\pm K^\mp$-pairs ($\pi K$-atoms) with the DIRAC experiment at the CERN-PS. The $\pi K$-atoms are produced by the 24 GeV/c proton beam in a thin Pt-target and the $\pi^\pm$ and $K^\mp$-mesons from the atom dissociation are analyzed in a two-arm magnetic spectrometer. The observed enhancement at low relative momentum corresponds to the production of 173 $\pm$ 54 $\pi K$-atoms. The mean life of $\pi K$-atoms is related to the s-wave $\pi K$-scattering lengths, the measurement of which is the goal of the experiment. From these first data we derive a lower limit for the mean life of 0.8 fs at 90% confidence level.Comment: 15 pages, 9 figure

Evidence-based guidelines for use of probiotics in preterm neonates

<p>Abstract</p> <p>Background</p> <p>Current evidence indicates that probiotic supplementation significantly reduces all-cause mortality and definite necrotising enterocolitis without significant adverse effects in preterm neonates. As the debate about the pros and cons of routine probiotic supplementation continues, many institutions are satisfied with the current evidence and wish to use probiotics routinely. Because of the lack of detail on many practical aspects of probiotic supplementation, clinician-friendly guidelines are urgently needed to optimise use of probiotics in preterm neonates.</p> <p>Aim</p> <p>To develop evidence-based guidelines for probiotic supplementation in preterm neonates.</p> <p>Methods</p> <p>To develop core guidelines on use of probiotics, including strain selection, dose and duration of supplementation, we primarily used the data from our recent updated systematic review of randomised controlled trials. For equally important issues including strain identification, monitoring for adverse effects, product format, storage and transport, and regulatory hurdles, a comprehensive literature search, covering the period 1966-2010 without restriction on the study design, was conducted, using the databases PubMed and EMBASE, and the proceedings of scientific conferences; these data were used in our updated systematic review.</p> <p>Results</p> <p>In this review, we present guidelines, including level of evidence, for the practical aspects (for example, strain selection, dose, duration, clinical and laboratory surveillance) of probiotic supplementation, and for dealing with non-clinical but important issues (for example, regulatory requirements, product format). Evidence was inadequate in some areas, and these should be a target for further research.</p> <p>Conclusion</p> <p>We hope that these evidence-based guidelines will help to optimise the use of probiotics in preterm neonates. Continued research is essential to provide answers to the current gaps in knowledge about probiotics.</p