301 research outputs found
Selección de sensores para la adquisición de datos atmosféricos utilizando la plataforma de hardware libre arduino
El Cambio Climático desempeña un papel crucial en la calidad de vida y el desarrollo de las actividades humanas. Esto significa que la adquisición de parámetros meteorológicos es importante para conocer los efectos que tienen sobre las personas. Se ha realizado un estudio para la selección de los sensores con mayor precisión y mejor correlación con respecto a la estación meteorológica Davis Vantage Pro 2 ubicada en el Laboratorio de FÃsica de la Atmósfera de la Universidad de Panamá;los mismos serán utilizados en la adquisición de datos de un sistema diseñado para
estudiar la estructura vertical de la Atmósfera en algún lugar de la geografÃa de nuestro paÃs, que aún está por determinarse. Estos sensores fueron utilizados con la
ayuda de la plataforma de hardware libre Arduino. Los parámetros atmosféricos estudiados en esta investigación fueron: temperatura, humedad relativa y presión.
Los sensores más adecuados, de acuerdo al parámetro medido, fueron: SHT15 para la temperatura ambiente y la humedad relativa y MS580312BA para la presión
atmosférica.
ABSTRACT
Climate Change plays a crucial role in the quality of life and the development of
human activities. This means that the acquisition of meteorological parameters is
important in order to know the effects they have on people. A study was carried out
to select the sensors with greater accuracy and better correlation with respect to the
Davis Vantage Pro 2 meteorological station located in the Laboratory of
Atmospheric Physics of the University of Panama; the same will be used in the
acquisition of data of a system designed to study the vertical structure of the
Atmosphere somewhere in the geography of our country, which is yet to be
determined. These sensors were used with the help of the free hardware platform
Arduino. The studied atmospheric parameters studied in this research were:
temperature, relative humidity and pressure. The most suitable sensors, according to
the parameter measured, were: SHT15 for ambient temperature and relative humidity
and MS580312BA for atmospheric pressure
Water and soil losses under different patterns of simulated rainfall and soil cover conditions
Este trabalho foi realizado com o objetivo de determinar as perdas de solo e água em um Argissolo Vermelho-Amarelo, submetido a quatro diferentes padrões de precipitação de chuva simulada e duas condições de cobertura: área com solo descoberto e com palhada após plantio de milho. O experimento foi conduzido no Campo Experimental da Embrapa-Agrobiologia, localizado no municÃpio de Seropédica-RJ, e consistiu na aplicação de chuvas simuladas com diferentes padrões, caracterizados como avançado (AV), intermediário (IN), atrasado (AT) e constante (CT), em uma área amostral de 0,80 m de largura por 1,0 m de comprimento. Utilizando um simulador de chuvas portátil, foram aplicadas chuvas com 30 mm de lâmina total durante 60 minutos. Nos padrões com intensidade variada, o pico de precipitação foi de 110 mm h-1. Os resultados obtidos possibilitaram concluir que a cobertura do solo com resÃduos de milho reduziu substancialmente as taxas e perdas de água e solo, principalmente para o padrão de chuva constante, indicando que a palhada deixada sobre o solo após a colheita auxilia de maneira efetiva no controle da erosão.This study was carried out in order to determine the soil and water losses in a Yellow-red Ultisol, under four different rainfall patterns and two conditions of soil cover: area with soil uncovered and with straw after corn planting. The experiment was conducted at the experimental field of Embrapa Agrobiologia, located at Seropedica municipality, State of Rio de Janeiro, Brazil. The treatments consisted in application of simulated rainfall using variable intensity classified in different patterns as: advanced (AV), intermediate (IN), delayed (AT), and constant (CT), in a plots with 0.8 m of width and 1.0 m of length. Using a portable rainfall simulator rainfall with 30 mm total depth during 60 minutes was applied. For the patterns with varied intensity, the peak of precipitation was 110 mm h(-1). The results showed the cover of the soil with corn stubble substantially reduced the rates and the soil and water losses, mainly for the pattern of constant rainfall, indicating that the residues left on the ground after harvest helps effectively in the erosion control
Eggplant crop in no tillage system under different irrigation depths
Este estudo foi conduzido no municÃpio de Seropédica, RJ, com o objetivo de se determinar, em cultivo orgânico e sistema de plantio direto, a produtividade da cultura da berinjela sob diferentes lâminas de irrigação e sistemas de cultivo (consorciada com leguminosa e solteira). O delineamento experimental adotado foi o de blocos ao acaso, no esquema de parcela subdividida com quatro repetições caracterizando, na parcela, os tratamentos equivalentes à lâmina de irrigação (40; 70; 100 e 120% ETc) e, na subparcela, os sistemas de cultivo consorciado com feijão caupi e solteiro. Ambos os sistemas de cultivo não influenciaram a produtividade final da berinjela; no entanto, considerando as diferentes lâminas, a maior produtividade comercial foi de 65,41 Mg ha-1, obtida para uma lâmina total de 690,04 mm (106,8% ETc). A menor lâmina aplicada resultou em qualidade inferior dos frutos em relação à s maiores lâminas, sendo a taxa de descarte dos frutos de 3 e 14%, respectivamente, para a maior e a menor lâmina.This study was carried out in the municipality of Seropedica-RJ, in order to determine, under organic farming and no tillage system, the yield of eggplants under different irrigation depths and cropping systems (intercropped with legumes and alone). The experimental design was in randomized blocks in a split plot design with four replications. The plots were characterized by the treatments corresponding to different water depths (40, 70, 100, 120% ETc), and the sub plots, the intercropping systems with cowpea and eggplant alone. Cropping systems did not influence the final yield of eggplant. However, considering the different irrigation depths, the highest commercial yield (65.41 Mg ha(-1)) was obtained for a total depth of 690.04 mm (106.8% ETc). The lower applied depth provided lower quality of fruit compared with that observed in the higher depths. The rate of fruit discard was 3 and 14%, respectively, for the higher and lower depths of irrigation
B cell–adaptive immune profile in emphysema-predominant chronic obstructive pulmonary disease
Cigarette smoke, the major risk factor for COPD in developed countries, causes pulmonary inflammation that persists long after smoking cessation, suggesting self-perpetuating adaptive immune responses similar to those that occur in autoimmune diseases. Increases in the number and size of B cell–rich lymphoid follicles (LFs) have been shown in patients in severe stages of COPD (4), and increased B-cell products (autoantibodies) have been observed in the blood and lungs of patients with COPD (5, 6). Oligoclonal rearrangement of the immunoglobulin genes has been observed in B cells isolated from COPD LFs, suggesting that a specific antigenic stimulation drives B-cell proliferation. Consistently, we have shown that in the COPD lung, there is an overexpression of BAFF (B-cell activation factor of the TNF family), which is a key regulator of B-cell homeostasis in several autoimmune diseases (7) and is involved in the growth of LFs in COPD. However, a network analysis of lung transcriptomics showed that a prominent B-cell molecular signature characterized emphysema preferentially but was absent in AD independently of the degree of airflow limitation (8). In the current study, we investigated the correlation between B-cell responses in lung tissue from patients with COPD and healthy smokers, and the extent of emphysema versus airflow limitation
Induced pseudoscalar coupling of the proton weak interaction
The induced pseudoscalar coupling is the least well known of the weak
coupling constants of the proton's charged--current interaction. Its size is
dictated by chiral symmetry arguments, and its measurement represents an
important test of quantum chromodynamics at low energies. During the past
decade a large body of new data relevant to the coupling has been
accumulated. This data includes measurements of radiative and non radiative
muon capture on targets ranging from hydrogen and few--nucleon systems to
complex nuclei. Herein the authors review the theoretical underpinnings of
, the experimental studies of , and the procedures and uncertainties
in extracting the coupling from data. Current puzzles are highlighted and
future opportunities are discussed.Comment: 58 pages, Latex, Revtex4, prepared for Reviews of Modern Physic
Prophylactic Treatment With Simvastatin Modulates the Immune Response and Increases Animal Survival Following Lethal Sepsis Infection
Chronic use of statins may have anti-inflammatory action, promoting immunomodulation and survival in patients with sepsis. This study aimed to analyze the effects of pretreatment with simvastatin in lethal sepsis induced by cecal ligation and puncture (CLP). Male Swiss mice received prophylactic treatment with simvastatin or pyrogen-free water orally in a single daily dose for 30 days. After this period, the CLP was performed. Naïve and Sham groups were performed as non-infected controls. Animal survival was monitored for 60 h after the CLP. Half of mice were euthanized after 12 h to analyze colony-forming units (CFUs); hematological parameters; production of IL-10, IL-12, IL-6, TNF-α, IFN-γ, and MCP-1; cell counts on peritoneum, bronchoalveolar lavage (BAL), bone marrow, spleen, and mesenteric lymph node; immunephenotyping of T cells and antigen presenting cells and production of hydrogen peroxide (H2O2). Simvastatin induced an increase in survival and a decrease in the CFU count on peritoneum and on BAL cells number, especially lymphocytes. There was an increase in the platelets and lymphocytes number in the Simvastatin group when compared to the CLP group. Simvastatin induced a greater activation and proliferation of CD4+ T cells, as well as an increase in IL-6 and MCP-1 production, in chemotaxis to the peritoneum and in H2O2 secretion at this site. These data suggest that simvastatin has an impact on the survival of animals, as well as immunomodulatory effects in sepsis induced by CLP in mice
Functional display of heterotetrameric human protein kinase CK2 on Escherichia coli: a novel tool for drug discovery
Effects of ranolazine on astrocytes and neurons in primary culture
Ranolazine (Rn) is an antianginal agent used for the treatment of chronic angina pectoris when angina is not adequately controlled by other drugs. Rn also acts in the central nervous system and it has been proposed for the treatment of pain and epileptic disorders. Under the hypothesis that ranolazine could act as a neuroprotective drug, we studied its effects on astrocytes and neurons in primary culture. We incubated rat astrocytes and neurons in primary cultures for 24 hours with Rn (10−7, 10−6 and 10−5 M). Cell viability and proliferation were measured using trypan blue exclusion assay, MTT conversion assay and LDH release assay. Apoptosis was determined by Caspase 3 activity assay. The effects of Rn on proinflammatory mediators IL-β and TNF-α was determined by ELISA technique, and protein expression levels of Smac/Diablo, PPAR-γ, Mn-SOD and Cu/Zn-SOD by western blot technique. In cultured astrocytes, Rn significantly increased cell viability and proliferation at any concentration tested, and decreased LDH leakage, Smac/Diablo expression and Caspase 3 activity indicating less cell death. Rn also increased anti-inflammatory PPAR-γ protein expression and reduced pro-inflammatory proteins IL-1 β and TNFα levels. Furthermore, antioxidant proteins Cu/Zn-SOD and Mn-SOD significantly increased after Rn addition in cultured astrocytes. Conversely, Rn did not exert any effect on cultured neurons. In conclusion, Rn could act as a neuroprotective drug in the central nervous system by promoting astrocyte viability, preventing necrosis and apoptosis, inhibiting inflammatory phenomena and inducing anti-inflammatory and antioxidant agents
Leptin Administration Favors Muscle Mass Accretion by Decreasing FoxO3a and Increasing PGC-1α in ob/ob Mice
Absence of leptin has been associated with reduced skeletal muscle mass in leptin-deficient ob/ob mice. The aim of our study was to examine the effect of leptin on the catabolic and anabolic pathways regulating muscle mass. Gastrocnemius, extensor digitorum longus and soleus muscle mass as well as fiber size were significantly lower in ob/ob mice compared to wild type littermates, being significantly increased by leptin administration (P<0.001). This effect was associated with an inactivation of the muscle atrophy-related transcription factor forkhead box class O3 (FoxO3a) (P<0.05), and with a decrease in the protein expression levels of the E3 ubiquitin-ligases muscle atrophy F-box (MAFbx) (P<0.05) and muscle RING finger 1 (MuRF1) (P<0.05). Moreover, leptin increased (P<0.01) protein expression levels of peroxisome proliferator-activated receptor γ coactivator-1α (PGC-1α), a regulator of muscle fiber type, and decreased (P<0.05) myostatin protein, a negative regulator of muscle growth. Leptin administration also activated (P<0.01) the regulators of cell cycle progression proliferating cell nuclear antigen (PCNA) and cyclin D1, and increased (P<0.01) myofibrillar protein troponin T. The present study provides evidence that leptin treatment may increase muscle mass of ob/ob mice by inhibiting myofibrillar protein degradation as well as enhancing muscle cell proliferation
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