562 research outputs found

    Review of Classroom Action: Human Rights, Critical Activism, and Community-Based Education

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    Book review of Classroom Action: Human Rights, Critical Activism, and Community-Based Education by Ajay Heble, ed. Classroom Action poses questions that can and should be of interest to archivists and special collections librarians, particularly those interested in social justice education, radical teaching practices, and community partnerships

    Archival Vaudeville: Rethinking Outreach with Collaborative Programming

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    When a group of archivists in Pittsburgh started meeting for happy hours, talk inevitably turned to the great things we were working on and how we wished more people knew about the archives found in our city. Comparing notes quickly turned to making plans for a public program that would allow local archivists to introduce themselves and their repositories to an audience beyond the circled wagons of our profession. In planning for this event, several decisions were made at a theoretical level that had real impact on the structure and success of the program. The loose formula created by the program planners could be adapted by other archives who wish to expand the reach of their repository but who have neither the funding for outreach nor a large enough staff to undertake such a program on their own

    Born-Digital Preservation: The Art of Archiving Photos With Script and Batch Processing

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    With our IT department preparing to upgrade the University of Georgia’s Alexander Campbell King Law Library (UGA Law Library) website from Drupal 7 to 8 this fall, a web developer, an archivist, and a librarian teamed up a year ago to make plans for preserving thousands of born-digital images. We wanted to harvest photographs housed only in web-based photo galleries on the law school website and import them into our repository’s collection. The problem? There were five types of online photo galleries, and our current repository did not include appropriate categories for all of the photographs. The solution? Expand our archives photo series structure in Digital Commons, write and run scripts to automate the gathering of image file URLs and basic metadata, and then clean up the spreadsheets to batch load it all into the collection

    Total hip replacement for the treatment of end stage arthritis of the hip : a systematic review and meta-analysis

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    Background: Evolvements in the design, fixation methods, size, and bearing surface of implants for total hip replacement (THR) have led to a variety of options for healthcare professionals to consider. The need to determine the most optimal combinations of THR implant is warranted. This systematic review evaluated the clinical effectiveness of different types of THR used for the treatment of end stage arthritis of the hip. Methods: A comprehensive literature search was undertaken in major health databases. Randomised controlled trials (RCTs) and systematic reviews published from 2008 onwards comparing different types of primary THR in patients with end stage arthritis of the hip were included. Results: Fourteen RCTs and five systematic reviews were included. Patients experienced significant post-THR improvements in Harris Hip scores, but this did not differ between impact types. There was a reduced risk of implant dislocation after receiving a larger femoral head size (36 mm vs. 28 mm; RR = 0.17, 95% CI: 0.04, 0.78) or cemented cup (vs. cementless cup; pooled odds ratio: 0.34, 95% CI: 0.13, 0.89). Recipients of cross-linked vs. conventional polyethylene cup liners experienced reduced femoral head penetration and revision. There was no impact of femoral stem fixation and cup shell design on implant survival rates. Evidence on mortality and complications (aseptic loosening, femoral fracture) was inconclusive. Conclusions: The majority of evidence was inconclusive due to poor reporting, missing data, or uncertainty in treatment estimates. The findings warrant cautious interpretation given the risk of bias (blinding, attrition), methodological limitations (small sample size, low event counts, short follow-up), and poor reporting. Long-term pragmatic RCTs are needed to allow for more definitive conclusions. Authors are encouraged to specify the minimal clinically important difference and power calculation for their primary outcome(s) as well CONSORT, PRISMA and STROBE guidelines to ensure better reporting and more reliable production and assessment of evidence

    Survey of southern Missouri Plethodontidae in Ozark caves

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    Plethodontidae is a large family of salamanders with a distribution ranging from eastern North Americato northern South America. Three genera and nine species occur in Missouri, most of which are typically found in cavesfor at least part of their lives. These species have been recorded to emerge from hibernation in early April and throughoutMay. This study shares the species abundance and diversity in ten Missouri Ozark caves: seven near St. Louis andthree near Springfield. Each cave was surveyed at least once between November 2021 and September 2022 using visualencounter surveys. Observational data were recorded without handling any individuals to minimize disturbance. Thethree caves near St. Louis had few to no salamanders present in early April, despite optimal weather conditions, buttended to have larger populations throughout the summer. Two caves near Springfield held at least a dozen individualsof multiple species in mid-April. Few individuals were recorded in the most southwestern cave sampled, potentiallydue to pollution or recent flooding. Our findings could aid others studying plethodontid salamanders to determine theprime conditions for emergence from hibernation, optimal habitats for different species in each cave zone, and potentialbiological or chemical impacts that could affect salamander abundance in caves

    The latent structure of cognitive and emotional empathy in individuals with autism, first-degree relatives and typical individuals

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    BACKGROUND: Empathy is a vital component for social understanding involving the ability to recognise emotion (cognitive empathy) and provide an appropriate affective response (emotional empathy). Autism spectrum conditions have been described as disorders of empathy. First-degree relatives may show some mild traits of the autism spectrum, the broader autism phenotype (BAP). Whether both cognitive and emotional empathy, rather than cognitive empathy alone, are impaired in autism and the BAP is still under debate. Moreover the association between various aspects of empathy is unclear. This study aims to examine the relationship between different components of empathy across individuals with varying levels of genetic vulnerability to autism. METHODS: Factor analyses utilising questionnaire and performance-based task data were implemented among individuals with autism, parents of a child with autism and controls. The relationship between performance-based tasks and behavioural measures of empathy was also explored. RESULTS: A four-factor model including cognitive empathy, emotional empathy, social skills and a performance-based factor fitted the data best irrespective of genetic vulnerability. Individuals with autism displayed impairment on all four factors, with parents showing intermediate difficulties. Performance-based measures of empathy were related in almost equal magnitude to cognitive and emotional empathy latent factors and the social skills factor. CONCLUSIONS: This study suggests individuals with autism have difficulties with multiple facets of empathy, while parents show intermediate impairments, providing evidence for a quantitative BAP. Impaired scores on performance-based measures of empathy, often thought to be pure measures of cognitive empathy, were also related to much wider empathy difficulties than impairments in cognitive empathy alone

    Belimumab : a technological advance for systemic lupus erythematosus patients? Report of a systematic review and meta-analysis

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    Objectives: To undertake a systematic review and meta-analysis to investigate clinical effectiveness of belimumab for patients with systemic lupus erythematosus (SLE) and antinuclear and/or anti-double-stranded DNA (dsDNA) autoantibodies. Methods: We searched eight electronic databases and reference lists for randomised controlled trials (RCTs) of belimumab against placebo or best supportive care. Quality assessment and random effects meta-analysis were undertaken. Design: A meta-analysis of RCTs. Participants: 2133 SLE patients. Primary and secondary outcome measures: SLE Responder Index (SRI) at week 52. Results: Three double-blind placebo-controlled RCTs (L02, BLISS-52 BLISS-76) investigated 2133 SLE patients. BLISS-52 and BLISS-76 trials recruited patients with antinuclear and/or anti-dsDNA autoantibodies and demonstrated belimumab effectiveness for the SRI at week 52. Ethnicity and geographical location of participants varied considerably between BLISS trials. Although tests for statistical heterogeneity were negative, BLISS-52 results were systematically more favourable for all measured outcomes. Meta-analysis of pooled 52-week SRI BLISS results showed benefit for belimumab (OR 1.63, 95% CI 1.27 to 2.09). By week 76, the primary SRI outcome in BLISS-76 was not statistically significant (OR 1.31, 95% CI 0.919 to 1.855)

    Effects of dietary deoxynivalenol or ochratoxin A on performance and selected health indices in Atlantic salmon (Salmo salar)

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    Post-smolt Atlantic salmon (Salmo salar) were fed with standard feed added one of five concentrations of either pure deoxynivalenol (DON; 0.5–6 mg/kg) or pure ochratoxin A (OTA; 0.2–2.4 mg/kg), or no added toxins for up to 8 weeks. Performance effects (feed intake, feed efficiency, gain, length and condition factor), various clinical biochemical parameters, packed cell volume and vaccination response against Aeromonas salmonicidae were all inversely correlated with DON dose, whereas relative liver weight increased with DON dose. In fish fed OTA, however, the effects at the doses tested were rather small. We observed no effects of OTA exposure on performance parameters, but some clinical biochemical parameters tended to increase with OTA dose primarily at 3 weeks, and compared with controls OTA exposure caused increased mRNA expression of two immune markers in the spleen. No liver histopathological effects were found from DON or OTA exposure. For DON, we derived a BMDL20 of 0.3 mg/kg feed for reduced total protein in plasma, a BMDL5 of 0.5 mg/kg feed for reduced condition factor, and a NOAEL of 1 mg/kg feed for DON. For OTA, a BMDL or NOAEL could not be derived (>2.4 mg/kg).publishedVersio

    In which context and for whom can interventions improve leadership of surgical trainees, surgeons and surgical teams and why: a realist review protocol [version 1; peer review: 3 approved, 1 approved with reservations]

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    Background: Improving effective leadership of individuals, groups, and healthcare organisations is essential for improving surgical performance and indirectly improving health outcomes for patients. Numerous systematic reviews have been conducted which seek to determine the effectiveness of specific leadership interventions across a range of disciplines and healthcare outcomes. The purpose of this realist review is to systematically synthesise the literature which examines in which context and for whom leadership interventions improve leadership of surgeons, surgical teams, and trainees. Methods: Several approaches will be used to iteratively search the scientific and grey literature to identify relevant evidence. Selected articles will inform the development of a programme theory that seeks to explain in which context and for whom interventions can improve leadership of surgical trainees, surgeons, and surgical teams. Next, empirical studies will be searched systematically in order to test and, where necessary, refine the theory. Once theoretical saturation has been achieved, recommendations for advancing leadership in surgery will be developed. Stakeholder and patient and public consultations will contribute to the development of the programme theory. The review will be written up according to the Realist And Meta-narrative Evidence Synthesis: Evolving Standards publication standards. No ethical review will be required for the conduct of this realist review. Discussion: The knowledge gained from this review will provide evidence-based guidance for those planning or designing leadership interventions in surgery. The recommendations will help policymakers, educationalists, healthcare providers, and those delivering or planning leadership development programmes across the surgical disciplines to design interventions that are acceptable to the surgical community and successful in improving surgical leadership.  PROSPERO registration: CRD4202123070
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