429 research outputs found
Commentary: the role of cytologic analysis of voided urine in the work-up of asymptomatic microhematuria
Microscopic hematuria is a common finding in patients presenting to both primary care doctors as well as urologists. Sources of microscopic hematuria include infection, stones, inflammatory disorders as well as cancer of the genitourinary tract, particularly urothelial cancer. A primary focus in the urologic workup of hematuria is to rule out cancer. This is done using radiographic studies as well as procedures such as cystoscopy and bladder biopsy. As the authors state in their article titled "The utility of serial urinary cytology in the initial evaluation of the patient with microscopic hematuria", cytologic analysis of voided urine, though attractive due to its noninvasive nature, has been found to have the neither the sensitivity, cost-effectiveness, nor the ease of administration necessary to replace more invasive diagnostics in the evaluation of microscopic hematuria
The Impact of a 4th Generation on Mixing and CP Violation in the Charm System
We study D0-D0 mixing in the presence of a fourth generation of quarks. In
particular, we calculate the size of the allowed CP violation which is found at
the observable level well beyond anything possible with CKM dynamics. We
calculate the semileptonic asymmetry a_SL and the mixing induced CP asymmetry
eta_fS_f which are correlated with each other. We also investigate the
correlation of eta_fS_f with a number of prominent observables in other mesonic
systems like epsilon'/epsilon, Br(K_L -> pi0 nu nu), Br(K+ -> pi+ nu nu),
Br(B_s ->mu+ mu-), Br(B_d -> mu+ mu-) and finally S_psi phi in the B_s system.
We identify a clear pattern of flavour and CP violation predicted by the SM4
model: While simultaneous large 4G effects in the K and D systems are possible,
accompanying large NP effects in the B_d system are disfavoured. However this
behaviour is not as pronounced as found for the LHT and RSc models. In contrast
to this, sizeable CP violating effects in the B_s system are possible unless
extreme effects in eta_fS_f are found, and Br(B_s ->mu+ mu-) can be strongly
enhanced regardless of the situation in the D system. We find that, on the
other hand, S_psi phi > 0.2 combined with the measured epsilon'/epsilon
significantly diminishes 4G effects within the D system.Comment: 22 pages, 23 figures, v2 (references added
Dark Matter from Minimal Flavor Violation
We consider theories of flavored dark matter, in which the dark matter
particle is part of a multiplet transforming nontrivially under the flavor
group of the Standard Model in a manner consistent with the principle of
Minimal Flavor Violation (MFV). MFV automatically leads to the stability of the
lightest state for a large number of flavor multiplets. If neutral, this
particle is an excellent dark matter candidate. Furthermore, MFV implies
specific patterns of mass splittings among the flavors of dark matter and
governs the structure of the couplings between dark matter and ordinary
particles, leading to a rich and predictive cosmology and phenomenology. We
present an illustrative phenomenological study of an effective theory of a
flavor SU(3)_Q triplet, gauge singlet scalar.Comment: 10 pages, 2 figures; v2: references added, minor changes to collider
analysis, conclusions unchange
Self-administered multi-level pregnancy tests in simplified follow-up of medical abortion in Tunisia
Sustained Release of Multiple Growth Factors from Injectable Polymeric System as a Novel Therapeutic Approach Towards Angiogenesis
The aim was to investigate that a bio-degradable alginate and poly lactide-co-glycolide (PLG) system capable of delivering growth factors sequentially would be superior to single growth factor delivery in promoting neovascularization and improving perfusion
Asymmetric Origin for Gravitino Relic Density in the Hybrid Gravity-Gauge Mediated Supersymmetry Breaking
We propose the hybrid gravity-gauge mediated supersymmetry breaking where the
gravitino mass is about several GeV. The strong constraints on supersymmetry
viable parameter space from the CMS and ATLAS experiments at the LHC can be
relaxed due to the heavy colored supersymmetric particles, and it is consistent
with null results in the dark matter (DM) direct search experiments such as
XENON100. In particular, the possible maximal flavor and CP violations from the
relatively small gravity mediation may naturally account for the recent LHCb
anomaly. In addition, because the gravitino mass is around the asymmetric DM
mass, we propose the asymmetric origin of the gravitino relic density and solve
the cosmological coincident problem on the DM and baryon densities \Omega_{\rm
DM}:\Omega_{B}\approx 5:1. The gravitino relic density arises from asymmetric
metastable particle (AMP) late decay. However, we show that there is no AMP
candidate in the minimal supersymmetric Standard Model (SM) due to the robust
gaugino/Higgsino mediated wash-out effects. Interestingly, AMP can be realized
in the well motivated supersymmetric SMs with vector-like particles or
continuous U(1)_R symmetry. Especially, the lightest CP-even Higgs boson mass
can be lifted in the supersymmetric SMs with vector-like particles.Comment: RevTex4, 21 pages, 1 figure, minor corrections, JHEP versio
Peaks and Troughs of Three-Dimensional Vestibulo-ocular Reflex in Humans
The three-dimensional vestibulo-ocular reflex (3D VOR) ideally generates compensatory ocular rotations not only with a magnitude equal and opposite to the head rotation but also about an axis that is collinear with the head rotation axis. Vestibulo-ocular responses only partially fulfill this ideal behavior. Because animal studies have shown that vestibular stimulation about particular axes may lead to suboptimal compensatory responses, we investigated in healthy subjects the peaks and troughs in 3D VOR stabilization in terms of gain and alignment of the 3D vestibulo-ocular response. Six healthy upright sitting subjects underwent whole body small amplitude sinusoidal and constant acceleration transients delivered by a six-degree-of-freedom motion platform. Subjects were oscillated about the vertical axis and about axes in the horizontal plane varying between roll and pitch at increments of 22.5° in azimuth. Transients were delivered in yaw, roll, and pitch and in the vertical canal planes. Eye movements were recorded in with 3D search coils. Eye coil signals were converted to rotation vectors, from which we calculated gain and misalignment. During horizontal axis stimulation, systematic deviations were found. In the light, misalignment of the 3D VOR had a maximum misalignment at about 45°. These deviations in misalignment can be explained by vector summation of the eye rotation components with a low gain for torsion and high gain for vertical. In the dark and in response to transients, gain of all components had lower values. Misalignment in darkness and for transients had different peaks and troughs than in the light: its minimum was during pitch axis stimulation and its maximum during roll axis stimulation. We show that the relatively large misalignment for roll in darkness is due to a horizontal eye movement component that is only present in darkness. In combination with the relatively low torsion gain, this horizontal component has a relative large effect on the alignment of the eye rotation axis with respect to the head rotation axis
Decoupling property of the supersymmetric Higgs sector with four doublets
In supersymmetric standard models with multi Higgs doublet fields,
selfcoupling constants in the Higgs potential come only from the D-terms at the
tree level. We investigate the decoupling property of additional two heavier
Higgs doublet fields in the supersymmetric standard model with four Higgs
doublets. In particular, we study how they can modify the predictions on the
quantities well predicted in the minimal supersymmetric standard model (MSSM),
when the extra doublet fields are rather heavy to be measured at collider
experiments. The B-term mixing between these extra heavy Higgs bosons and the
relatively light MSSM-like Higgs bosons can significantly change the
predictions in the MSSM such as on the masses of MSSM-like Higgs bosons as well
as the mixing angle for the two light CP-even scalar states. We first give
formulae for deviations in the observables of the MSSM in the decoupling region
for the extra two doublet fields. We then examine possible deviations in the
Higgs sector numerically, and discuss their phenomenological implications.Comment: 26 pages, 24 figures, text sligtly modified,version to appear in
Journal of High Energy Physic
Terahertz photometer to observe solar flares in continuum
Solar observations at sub-THz frequencies detected a new flare spectral
component peaking in the THz range, simultaneously with the well known
microwaves component, bringing challenging constraints for interpretation.
Higher THz frequencies observations are needed to understand the nature of the
mechanisms occurring in flares. A THz photometer system was developed to
observe outside the terrestrial atmosphere on stratospheric balloons or
satellites, or at exceptionally transparent ground stations. The telescope was
designed to observe the whole solar disk detecting small relative changes in
input temperature caused by flares at localized positions. A Golay cell
detector is preceded by low-pass filters to suppress visible and near IR
radiation, a band-pass filter, and a chopper. A prototype was assembled to
demonstrate the new concept and the system performance. It can detect
temperature variations smaller than 1 K for data sampled at a rate of
10/second, smoothed for intervals larger than 4 seconds. For a 76 mm aperture,
this corresponds to small solar burst intensities at THz frequencies. A system
with 3 and 7 THz photometers is being built for solar flare observations on
board of stratospheric balloon missions.Comment: 11 pages, 8 figures, accepted by Journal of Infrared, Millimeter, and
Terahertz Waves, 9 December 201
The association between antihypertensive drugs and glioma
We pursued an association between hypertension and gliomas by investigating whether antihypertensive drugs (AHD) are associated with an increased glioma risk by a population-based nested case–control study using the PHARMO database; this links dispensing records of prescription drugs to hospital discharge data on an individual basis. Pathological data were derived from the Dutch nationwide registry of histo- and cytopathology. A total of 306 glioma cases incident between 1997 and 2003 were matched to 1108 controls for year of birth, sex, geographical region and duration of follow-up. Exposure was defined as cumulative duration of AHD use and, in an alternative analysis, as cumulative dose. We estimated the magnitude of the association with conditional logistic regression analysis. Cumulative use of any AHD for more than 6 months was associated with an increased risk of glioma (OR 1.45; 95% CI 1.03–2.04). After stratification for different groups of AHD, no significantly increased risk of glioma was found for any class of AHD. After excluding a latency period of 3 years before the date of diagnosis, no association was found. In conclusion, the use of AHD seems to be associated with an increased risk of glioma, but this is probably not causal
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