Heavy Supersymmetric Particle Effects in Higgs Boson Production Associated with a Bottom Quark Pair at LHC and Tevatron

If all the supersymmetry particles (sparticles) except a light Higgs boson are too heavy to be directly produced at the Large Hadron Collider (LHC) and Tevatron, a possible way to reveal evidence for supersymmetry is through their virtual effects in other processes. We examine such supersymmetric QCD effects in bottom pair production associated with a light Higgs boson at the LHC and Tevatron. We find that if the relevant sparticles (gluinos and squarks) are well above the TeV scale, too heavy to be directly produced, they can still have sizable virtual effects in this process. For large $\tan\beta$, such residual effects can alter the production rate by as much as 40 percent, which should be observable in future measurements of this process.Comment: results for Tevatron added, version in PR

Transforming a Corner of a Light-Frame Wood Structure to a Set of Nonlinear Springs

The computational efficiency of a full-structure model for a light-frame building is enhanced by replacing the continuum of the detailed connections with rotational and translational nonlinear springs that are energetically equivalent between two bounds. This study examines the transformation from the physical exterior-wall-to-exterior-wall connection (a corner) of a light-frame wood structure, first, to a two-dimensional finite-element model and, then, to a set of nonlinear springs. Typical light-frame details are used as the starting point, and the product is the characteristic moment-rotation and load-displacement relationships for a 24-inch segment of the corner

The Rise Times of High and Low Redshift Type Ia Supernovae are Consistent

We present a self-consistent comparison of the rise times for low- and high-redshift Type Ia supernovae. Following previous studies, the early light curve is modeled using a t-squared law, which is then mated with a modified Leibundgut template light curve. The best-fit t-squared law is determined for ensemble samples of low- and high-redshift supernovae by fitting simultaneously for all light curve parameters for all supernovae in each sample. Our method fully accounts for the non-negligible covariance amongst the light curve fitting parameters, which previous analyses have neglected. Contrary to Riess et al. (1999), we find fair to good agreement between the rise times of the low- and high-redshift Type Ia supernovae. The uncertainty in the rise time of the high-redshift Type Ia supernovae is presently quite large (roughly +/- 1.2 days statistical), making any search for evidence of evolution based on a comparison of rise times premature. Furthermore, systematic effects on rise time determinations from the high-redshift observations, due to the form of the late-time light curve and the manner in which the light curves of these supernovae were sampled, can bias the high-redshift rise time determinations by up to +3.6/-1.9 days under extreme situations. The peak brightnesses - used for cosmology - do not suffer any significant bias, nor any significant increase in uncertainty.Comment: 18 pages, 4 figures, Accepted for publication in the Astronomical Journal. Also available at http://www.lbl.gov/~nugent/papers.html Typos were corrected and a few sentences were added for improved clarit

Vena cava inferior thrombosis detected by venous hum: a case report

We describe a patient in which a venous hum, heard during abdominal auscultation, lead to the diagnosis of a vena cava inferior thrombosis

Tests of the Accelerating Universe with Near-Infrared Observations of a High-Redshift Type Ia Supernova

We have measured the rest-frame B,V, and I-band light curves of a high-redshift type Ia supernova (SN Ia), SN 1999Q (z=0.46), using HST and ground-based near-infrared detectors. A goal of this study is the measurement of the color excess, E_{B-I}, which is a sensitive indicator of interstellar or intergalactic dust which could affect recent cosmological measurements from high-redshift SNe Ia. Our observations disfavor a 30% opacity of SN Ia visual light by dust as an alternative to an accelerating Universe. This statement applies to both Galactic-type dust (rejected at the 3.4 sigma confidence level) and greyer dust (grain size > 0.1 microns; rejected at the 2.3 to 2.6 sigma confidence level) as proposed by Aguirre (1999). The rest-frame $I$-band light cur ve shows the secondary maximum a month after B maximum typical of nearby SNe Ia of normal luminosi ty, providing no indication of evolution as a function of redshift out to z~0.5. A n expanded set of similar observations could improve the constraints on any contribution of extragalactic dust to the dimming of high-redshift SNe Ia.Comment: Accepted to the Astrophysical Journal, 12 pages, 2 figure

Lattice results for the decay constant of heavy-light vector mesons

We compute the leptonic decay constants of heavy-light vector mesons in the quenched approximation. The reliability of lattice computations for heavy quarks is checked by comparing the ratio of vector to pseudoscalar decay constant with the prediction of Heavy Quark Effective Theory in the limit of infinitely heavy quark mass. Good agreement is found. We then calculate the decay constant ratio for B mesons: $f_{B^*}/f_B= 1.01(0.01)(^{+0.04}_{-0.01})$. We also quote quenched $f_{B^*}=177(6)(17)$ MeV.Comment: 11 pages, 3 postscript figs., revtex; two references adde

Murine Fig4 is dispensable for muscle development but required for muscle function

Abstract Background Phosphatidylinositol phosphates (PIPs) are low-abundance phospholipids that participate in a range of cellular processes, including cell migration and membrane traffic. PIP levels and subcellular distribution are regulated by a series of lipid kinases and phosphatases. In skeletal muscle, PIPs and their enzymatic regulators serve critically important functions exemplified by mutations of the PIP phosphatase MTM1 in myotubular myopathy (MTM), a severe muscle disease characterized by impaired muscle structure and abnormal excitation–contraction coupling. FIG4 functions as a PIP phosphatase that participates in both the synthesis and breakdown of phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Mutation of FIG4 results in a severe neurodegenerative disorder in mice and a progressive peripheral polyneuropathy in humans. The effect of FIG4 mutation on skeletal muscle has yet to be examined. Methods Herein we characterize the impact of FIG4 on skeletal muscle development and function using the spontaneously occurring mouse mutant pale tremor (plt), a mouse line with a loss of function mutation in Fig4. Results In plt mice, we characterized abnormalities in skeletal muscle, including reduced muscle size and specific force generation. We also uncovered ultrastructural abnormalities and increased programmed cell death. Conversely, we detected no structural or functional abnormalities to suggest impairment of excitation–contraction coupling, a process previously shown to be influenced by PI(3,5)P2 levels. Conditional rescue of Fig4 mutation in neurons prevented overt muscle weakness and the development of obvious muscle abnormalities, suggesting that the changes observed in the plt mice were primarily related to denervation of skeletal muscle. On the basis of the ability of reduced FIG4 levels to rescue aspects of Mtmr2-dependent neuropathy, we evaluated the effect of Fig4 haploinsufficiency on the myopathy of Mtm1-knockout mice. Male mice with a compound Fig4 +/−/Mtm1 –/Y genotype displayed no improvements in muscle histology, muscle size or overall survival, indicating that FIG4 reduction does not ameliorate the Mtm1-knockout phenotype. Conclusions Overall, these data indicate that loss of Fig4 impairs skeletal muscle function but does not significantly affect its structural development.http://deepblue.lib.umich.edu/bitstream/2027.42/112676/1/13395_2013_Article_83.pd

Landscape Analysis for the Specimen Data Refinery

This report reviews the current state-of-the-art applied approaches on automated tools, services and workflows for extracting information from images of natural history specimens and their labels. We consider the potential for repurposing existing tools, including workflow management systems; and areas where more development is required. This paper was written as part of the SYNTHESYS+ project for software development teams and informatics teams working on new software-based approaches to improve mass digitisation of natural history specimens