Volatile compounds of wild cherry honey : bachelor thesis

U ovom završnom radu istražen je profil hlapljivih spojeva meda divlje trešnje, tj. određen je sastav i sadržaj hlapljivih spojeva. Za izolaciju hlapljivih spojeva korištena je metoda ekstrakcije i to ultrazvučna ekstrakcija i kontinuirana ekstrakcija tekuće-tekuće. U obje ekstrakcijske tehnike korišteno je isto otapalo, smjesa otapala pentan:dietil-eter 1:2, v/v. Analiza svih uzoraka je provedena plinskom kromatografijom–masenom spektrometrijom. Glavni sastojci u uzorku hlapljivih spojeva meda iz Kutjeva dobivenih ultrazvučnom ekstrakcijom su derivati benzena, metil-siringat, benzojeva kiselina i 4-vinilfenol, diterpenski alkohol izofitol i C 13 -norizoprenoid 4- hidroksi-3,5,5-trimetil-4-(3-okso-1-butenil)-2-cikloheksen-1-on. Glavni spoj među hlapljivim spojevima dobivenim ultrazvučnom ekstrakcijom (med iz Voćina) je diterpenski alkohol izofitol, a kvantitativno značajni sastojci su C 13 -norizoprenoid 4-hidroksi-3,5,5-trimetil-4-(3-okso-1-butenil)-2-cikloheksen-1-on (12,3 %), terpenski spoj kar-3-en-2,5-dion i derivat benzena 2-feniloctena kiselina. Derivati benzena su glavni sastojci u uzorku hlapljivih spojeva izoliranih ekstrakcijom tekuće-tekuće meda iz Kutjeva, a najzastupljeniji su 2-feniloctena kiselina i dibenzil. U istom tipu ekstrakta dobivenom iz meda iz Voćina dominantan spoj je C 13- norizoprenoid 4-hidroksi-3,5,5-trimetil-4-(3-okso-1-butenil)-2-cikloheksen-1- on, a slijedi diterpenski alkohol izofitol.In this bachelor thesis, the chemical profile i.e. composition and content of two samples of wild cherry honey volatiles was investigated. Wild cherry honey volatiles were isolated by two extraction methods, ultrasound assisted solvent extraction (USE) and continuous liquid-liquid extraction. In both cases, the organic solvent was a mixture of pentane:diethyl ether 1:2 v/v. Following the isolation, all the extracts were analyzed by gas chromatography-mass spectrometry (GC-MS). The main components of wild cherry honey volatiles (sample from Kutjevo) isolated by USE are benzene derivatives methyl syringate, benzoic acid and 4-vinylphenol, diterpene alcohol isophytol and C 13 - norisoprenoid 4-hydroxy-3,5,5-trimethyl-4-(3-oxo-1-butenyl)cyclohex-2-en-1-one. In the ultrasound solvent extract of wild cherry honey from Voćin diterpene alcohol isophytol is the main compound, followed by 4- hydroxy-3,5,5-trimethyl-4-(3-oxo-1-butenyl)cyclohex-2-en-1-one, terpene compound car-3-en-2,5-dione and benzene derivative 2-phenylacetic acid. Benzene derivatives are the dominant compounds among volatiles obtained by liquid-liquid extraction of honey from Kutjevo, with 2-phenylacetic acid and dibenzyl as the main components. The same type of extract made from Voćin honey is characterized by high content of C 13 -norisoprenoid 4-hydroxy-3,5,5-trimethyl-4- (3-oxo-1-butenyl)cyclohex-2-en-1-one followed by diterpene alcohol isophytol

Influence of selenium on glucosinolate profile in rocket sprouts : master thesis

Glukozinolati (β-tioglukozidni-N-hidroksisulfati) su velika grupa sekundarnih metabolita koji daju karakterističan gorki i oštri okus kupusnjačama te su njihovi razgradni produkti biološki aktivni spojevi. Razgradnja može biti termička, enzimska ili kemijska pri čemu nastaju brojni razgradni produkti kao što su tiocijanati i izotiocijanati. Klice rikule su nutritivno bogate, a prednost im je vrlo laki uzgoj. Klijanjem se nutrijenti u sjemenci razgrađuju na sastavne dijelove, razvija se klorofil i povećava se količina proteina, minerala i elemenata u tragovima. Dodatna prednost je da su bogate vitaminima, čiji se sadržaj povećava klijanjem, esencijalnim masnim kiselinama i vlaknima te imaju pozitivan učinak na organizam. Biljke nemaju potrebu za selenom i uglavnom ne podnose koncentracije veće od 10-100 μg/g suhe mase u tkivima, no vrste koje pripadaju obitelji Brassicaceae mogu akumulirati selen u tkivima i tolerirati koncentracije do 1000 μg/g suhe mase. Na taj način, biljke proizvode razne seleno metabolite koji mogu imati ulogu kao sredstva za sprječavanje raka. Istraživanja su pokazala da se u bočni lanac glukozinolata umjesto sumpora može ugraditi atom selena. U ovom diplomskom radu uzgojene su klice rikule te zalijevane otopinama selena različitih koncentracija (1; 2,5; 5; 7,5; 10 ppm). Razvoj biljaka praćen je tijekom 7 dana i jedino pri najvišoj koncentraciji selena nije došlo do razvoja biljke. Nakon sabiranja glukozinolati su izolirani ekstrakcijom 70%-tnim metanolom te analizirani UHPLC-DAD-MS/MS, a njihovi hlapljivi razgradni produkti su izolirani ekstrakcijom diklormetanom i identificirani GC-MS tehnikom. Identificirana su 4 glukozinolata: glukorafanin, glukoerucin, dimer glukosativina i 4-metoksiglukobrasicin, dok je GC-MS tehnikom identificiran erucin kao razgradni produkt glukoerucina.Glucosinolates (β-thioglucoside-N-hydroxysulfates) are a large group of secondary metabolites that give a characteristic bitter and pungent taste to cabbages and their degradation products are biologically active compounds. Degradation can be thermal, enzymatic, or chemical and it forms several degradation products such as thiocyanates and isothiocyanates. Rocket sprouts are nutritionally rich, and their advantage is very easy cultivation. By germination, the nutrients in the seed are broken down into their main components, chlorophyll develops and the amount of proteins, minerals and trace elements increases. An additional advantage is that they are rich in vitamins whose content increases with germination, essential fatty acids and fiber and have a positive effect on the body. Plants do not need selenium and generally do not tolerate concentrations higher than 10-100 μg/g dry weight in tissues, but species belonging to the Brassicaceae family can accumulate selenium in tissues and tolerate concentrations up to 1000 μg/g dry weight. In this way, plants produce various selenium metabolites that can play a role as a means of preventing cancer. Studies have shown that a selenium atom can be incorporated into the side chain of glucosinolates instead of sulfur. In this diploma thesis, rocket sprouts were grown and watered with selenium solutions of different concentrations (1; 2.5; 5; 7.5; 10 ppm). The development of the plants was monitored for 7 days, and only at the highest concentration of selenium the plant did not develop. After collection, glucosinolates were isolated by extraction with 70% methanol and analyzed by UHPLC-DAD-MS / MS, and their volatile degradation products were isolated by extraction with dichloromethane and identified by GC-MS technique. 4 glucosinolates were identified: glucoraphanin, glucoerucine, glucosatin dimer and 4-methoxyglucobrasicin, while GC-MS technique identified erucin which originate from degradation of glucoerucin

Volatile compounds of wild cherry honey : bachelor thesis

U ovom završnom radu istražen je profil hlapljivih spojeva meda divlje trešnje, tj. određen je sastav i sadržaj hlapljivih spojeva. Za izolaciju hlapljivih spojeva korištena je metoda ekstrakcije i to ultrazvučna ekstrakcija i kontinuirana ekstrakcija tekuće-tekuće. U obje ekstrakcijske tehnike korišteno je isto otapalo, smjesa otapala pentan:dietil-eter 1:2, v/v. Analiza svih uzoraka je provedena plinskom kromatografijom–masenom spektrometrijom. Glavni sastojci u uzorku hlapljivih spojeva meda iz Kutjeva dobivenih ultrazvučnom ekstrakcijom su derivati benzena, metil-siringat, benzojeva kiselina i 4-vinilfenol, diterpenski alkohol izofitol i C 13 -norizoprenoid 4- hidroksi-3,5,5-trimetil-4-(3-okso-1-butenil)-2-cikloheksen-1-on. Glavni spoj među hlapljivim spojevima dobivenim ultrazvučnom ekstrakcijom (med iz Voćina) je diterpenski alkohol izofitol, a kvantitativno značajni sastojci su C 13 -norizoprenoid 4-hidroksi-3,5,5-trimetil-4-(3-okso-1-butenil)-2-cikloheksen-1-on (12,3 %), terpenski spoj kar-3-en-2,5-dion i derivat benzena 2-feniloctena kiselina. Derivati benzena su glavni sastojci u uzorku hlapljivih spojeva izoliranih ekstrakcijom tekuće-tekuće meda iz Kutjeva, a najzastupljeniji su 2-feniloctena kiselina i dibenzil. U istom tipu ekstrakta dobivenom iz meda iz Voćina dominantan spoj je C 13- norizoprenoid 4-hidroksi-3,5,5-trimetil-4-(3-okso-1-butenil)-2-cikloheksen-1- on, a slijedi diterpenski alkohol izofitol.In this bachelor thesis, the chemical profile i.e. composition and content of two samples of wild cherry honey volatiles was investigated. Wild cherry honey volatiles were isolated by two extraction methods, ultrasound assisted solvent extraction (USE) and continuous liquid-liquid extraction. In both cases, the organic solvent was a mixture of pentane:diethyl ether 1:2 v/v. Following the isolation, all the extracts were analyzed by gas chromatography-mass spectrometry (GC-MS). The main components of wild cherry honey volatiles (sample from Kutjevo) isolated by USE are benzene derivatives methyl syringate, benzoic acid and 4-vinylphenol, diterpene alcohol isophytol and C 13 - norisoprenoid 4-hydroxy-3,5,5-trimethyl-4-(3-oxo-1-butenyl)cyclohex-2-en-1-one. In the ultrasound solvent extract of wild cherry honey from Voćin diterpene alcohol isophytol is the main compound, followed by 4- hydroxy-3,5,5-trimethyl-4-(3-oxo-1-butenyl)cyclohex-2-en-1-one, terpene compound car-3-en-2,5-dione and benzene derivative 2-phenylacetic acid. Benzene derivatives are the dominant compounds among volatiles obtained by liquid-liquid extraction of honey from Kutjevo, with 2-phenylacetic acid and dibenzyl as the main components. The same type of extract made from Voćin honey is characterized by high content of C 13 -norisoprenoid 4-hydroxy-3,5,5-trimethyl-4- (3-oxo-1-butenyl)cyclohex-2-en-1-one followed by diterpene alcohol isophytol

Volatile compounds of wild cherry honey : bachelor thesis

U ovom završnom radu istražen je profil hlapljivih spojeva meda divlje trešnje, tj. određen je sastav i sadržaj hlapljivih spojeva. Za izolaciju hlapljivih spojeva korištena je metoda ekstrakcije i to ultrazvučna ekstrakcija i kontinuirana ekstrakcija tekuće-tekuće. U obje ekstrakcijske tehnike korišteno je isto otapalo, smjesa otapala pentan:dietil-eter 1:2, v/v. Analiza svih uzoraka je provedena plinskom kromatografijom–masenom spektrometrijom. Glavni sastojci u uzorku hlapljivih spojeva meda iz Kutjeva dobivenih ultrazvučnom ekstrakcijom su derivati benzena, metil-siringat, benzojeva kiselina i 4-vinilfenol, diterpenski alkohol izofitol i C 13 -norizoprenoid 4- hidroksi-3,5,5-trimetil-4-(3-okso-1-butenil)-2-cikloheksen-1-on. Glavni spoj među hlapljivim spojevima dobivenim ultrazvučnom ekstrakcijom (med iz Voćina) je diterpenski alkohol izofitol, a kvantitativno značajni sastojci su C 13 -norizoprenoid 4-hidroksi-3,5,5-trimetil-4-(3-okso-1-butenil)-2-cikloheksen-1-on (12,3 %), terpenski spoj kar-3-en-2,5-dion i derivat benzena 2-feniloctena kiselina. Derivati benzena su glavni sastojci u uzorku hlapljivih spojeva izoliranih ekstrakcijom tekuće-tekuće meda iz Kutjeva, a najzastupljeniji su 2-feniloctena kiselina i dibenzil. U istom tipu ekstrakta dobivenom iz meda iz Voćina dominantan spoj je C 13- norizoprenoid 4-hidroksi-3,5,5-trimetil-4-(3-okso-1-butenil)-2-cikloheksen-1- on, a slijedi diterpenski alkohol izofitol.In this bachelor thesis, the chemical profile i.e. composition and content of two samples of wild cherry honey volatiles was investigated. Wild cherry honey volatiles were isolated by two extraction methods, ultrasound assisted solvent extraction (USE) and continuous liquid-liquid extraction. In both cases, the organic solvent was a mixture of pentane:diethyl ether 1:2 v/v. Following the isolation, all the extracts were analyzed by gas chromatography-mass spectrometry (GC-MS). The main components of wild cherry honey volatiles (sample from Kutjevo) isolated by USE are benzene derivatives methyl syringate, benzoic acid and 4-vinylphenol, diterpene alcohol isophytol and C 13 - norisoprenoid 4-hydroxy-3,5,5-trimethyl-4-(3-oxo-1-butenyl)cyclohex-2-en-1-one. In the ultrasound solvent extract of wild cherry honey from Voćin diterpene alcohol isophytol is the main compound, followed by 4- hydroxy-3,5,5-trimethyl-4-(3-oxo-1-butenyl)cyclohex-2-en-1-one, terpene compound car-3-en-2,5-dione and benzene derivative 2-phenylacetic acid. Benzene derivatives are the dominant compounds among volatiles obtained by liquid-liquid extraction of honey from Kutjevo, with 2-phenylacetic acid and dibenzyl as the main components. The same type of extract made from Voćin honey is characterized by high content of C 13 -norisoprenoid 4-hydroxy-3,5,5-trimethyl-4- (3-oxo-1-butenyl)cyclohex-2-en-1-one followed by diterpene alcohol isophytol

Influence of selenium on glucosinolate profile in rocket sprouts : master thesis

Glukozinolati (β-tioglukozidni-N-hidroksisulfati) su velika grupa sekundarnih metabolita koji daju karakterističan gorki i oštri okus kupusnjačama te su njihovi razgradni produkti biološki aktivni spojevi. Razgradnja može biti termička, enzimska ili kemijska pri čemu nastaju brojni razgradni produkti kao što su tiocijanati i izotiocijanati. Klice rikule su nutritivno bogate, a prednost im je vrlo laki uzgoj. Klijanjem se nutrijenti u sjemenci razgrađuju na sastavne dijelove, razvija se klorofil i povećava se količina proteina, minerala i elemenata u tragovima. Dodatna prednost je da su bogate vitaminima, čiji se sadržaj povećava klijanjem, esencijalnim masnim kiselinama i vlaknima te imaju pozitivan učinak na organizam. Biljke nemaju potrebu za selenom i uglavnom ne podnose koncentracije veće od 10-100 μg/g suhe mase u tkivima, no vrste koje pripadaju obitelji Brassicaceae mogu akumulirati selen u tkivima i tolerirati koncentracije do 1000 μg/g suhe mase. Na taj način, biljke proizvode razne seleno metabolite koji mogu imati ulogu kao sredstva za sprječavanje raka. Istraživanja su pokazala da se u bočni lanac glukozinolata umjesto sumpora može ugraditi atom selena. U ovom diplomskom radu uzgojene su klice rikule te zalijevane otopinama selena različitih koncentracija (1; 2,5; 5; 7,5; 10 ppm). Razvoj biljaka praćen je tijekom 7 dana i jedino pri najvišoj koncentraciji selena nije došlo do razvoja biljke. Nakon sabiranja glukozinolati su izolirani ekstrakcijom 70%-tnim metanolom te analizirani UHPLC-DAD-MS/MS, a njihovi hlapljivi razgradni produkti su izolirani ekstrakcijom diklormetanom i identificirani GC-MS tehnikom. Identificirana su 4 glukozinolata: glukorafanin, glukoerucin, dimer glukosativina i 4-metoksiglukobrasicin, dok je GC-MS tehnikom identificiran erucin kao razgradni produkt glukoerucina.Glucosinolates (β-thioglucoside-N-hydroxysulfates) are a large group of secondary metabolites that give a characteristic bitter and pungent taste to cabbages and their degradation products are biologically active compounds. Degradation can be thermal, enzymatic, or chemical and it forms several degradation products such as thiocyanates and isothiocyanates. Rocket sprouts are nutritionally rich, and their advantage is very easy cultivation. By germination, the nutrients in the seed are broken down into their main components, chlorophyll develops and the amount of proteins, minerals and trace elements increases. An additional advantage is that they are rich in vitamins whose content increases with germination, essential fatty acids and fiber and have a positive effect on the body. Plants do not need selenium and generally do not tolerate concentrations higher than 10-100 μg/g dry weight in tissues, but species belonging to the Brassicaceae family can accumulate selenium in tissues and tolerate concentrations up to 1000 μg/g dry weight. In this way, plants produce various selenium metabolites that can play a role as a means of preventing cancer. Studies have shown that a selenium atom can be incorporated into the side chain of glucosinolates instead of sulfur. In this diploma thesis, rocket sprouts were grown and watered with selenium solutions of different concentrations (1; 2.5; 5; 7.5; 10 ppm). The development of the plants was monitored for 7 days, and only at the highest concentration of selenium the plant did not develop. After collection, glucosinolates were isolated by extraction with 70% methanol and analyzed by UHPLC-DAD-MS / MS, and their volatile degradation products were isolated by extraction with dichloromethane and identified by GC-MS technique. 4 glucosinolates were identified: glucoraphanin, glucoerucine, glucosatin dimer and 4-methoxyglucobrasicin, while GC-MS technique identified erucin which originate from degradation of glucoerucin

Influence of selenium on glucosinolate profile in rocket sprouts : master thesis

Glukozinolati (β-tioglukozidni-N-hidroksisulfati) su velika grupa sekundarnih metabolita koji daju karakterističan gorki i oštri okus kupusnjačama te su njihovi razgradni produkti biološki aktivni spojevi. Razgradnja može biti termička, enzimska ili kemijska pri čemu nastaju brojni razgradni produkti kao što su tiocijanati i izotiocijanati. Klice rikule su nutritivno bogate, a prednost im je vrlo laki uzgoj. Klijanjem se nutrijenti u sjemenci razgrađuju na sastavne dijelove, razvija se klorofil i povećava se količina proteina, minerala i elemenata u tragovima. Dodatna prednost je da su bogate vitaminima, čiji se sadržaj povećava klijanjem, esencijalnim masnim kiselinama i vlaknima te imaju pozitivan učinak na organizam. Biljke nemaju potrebu za selenom i uglavnom ne podnose koncentracije veće od 10-100 μg/g suhe mase u tkivima, no vrste koje pripadaju obitelji Brassicaceae mogu akumulirati selen u tkivima i tolerirati koncentracije do 1000 μg/g suhe mase. Na taj način, biljke proizvode razne seleno metabolite koji mogu imati ulogu kao sredstva za sprječavanje raka. Istraživanja su pokazala da se u bočni lanac glukozinolata umjesto sumpora može ugraditi atom selena. U ovom diplomskom radu uzgojene su klice rikule te zalijevane otopinama selena različitih koncentracija (1; 2,5; 5; 7,5; 10 ppm). Razvoj biljaka praćen je tijekom 7 dana i jedino pri najvišoj koncentraciji selena nije došlo do razvoja biljke. Nakon sabiranja glukozinolati su izolirani ekstrakcijom 70%-tnim metanolom te analizirani UHPLC-DAD-MS/MS, a njihovi hlapljivi razgradni produkti su izolirani ekstrakcijom diklormetanom i identificirani GC-MS tehnikom. Identificirana su 4 glukozinolata: glukorafanin, glukoerucin, dimer glukosativina i 4-metoksiglukobrasicin, dok je GC-MS tehnikom identificiran erucin kao razgradni produkt glukoerucina.Glucosinolates (β-thioglucoside-N-hydroxysulfates) are a large group of secondary metabolites that give a characteristic bitter and pungent taste to cabbages and their degradation products are biologically active compounds. Degradation can be thermal, enzymatic, or chemical and it forms several degradation products such as thiocyanates and isothiocyanates. Rocket sprouts are nutritionally rich, and their advantage is very easy cultivation. By germination, the nutrients in the seed are broken down into their main components, chlorophyll develops and the amount of proteins, minerals and trace elements increases. An additional advantage is that they are rich in vitamins whose content increases with germination, essential fatty acids and fiber and have a positive effect on the body. Plants do not need selenium and generally do not tolerate concentrations higher than 10-100 μg/g dry weight in tissues, but species belonging to the Brassicaceae family can accumulate selenium in tissues and tolerate concentrations up to 1000 μg/g dry weight. In this way, plants produce various selenium metabolites that can play a role as a means of preventing cancer. Studies have shown that a selenium atom can be incorporated into the side chain of glucosinolates instead of sulfur. In this diploma thesis, rocket sprouts were grown and watered with selenium solutions of different concentrations (1; 2.5; 5; 7.5; 10 ppm). The development of the plants was monitored for 7 days, and only at the highest concentration of selenium the plant did not develop. After collection, glucosinolates were isolated by extraction with 70% methanol and analyzed by UHPLC-DAD-MS / MS, and their volatile degradation products were isolated by extraction with dichloromethane and identified by GC-MS technique. 4 glucosinolates were identified: glucoraphanin, glucoerucine, glucosatin dimer and 4-methoxyglucobrasicin, while GC-MS technique identified erucin which originate from degradation of glucoerucin

Iron(III)-Catalyzed Synthesis of 2-Alkyl Homoallyl Sulfonyl Amides: Antiproliferative Study and Reactivity Scope of Aza-Prins Cyclization

A direct, catalytic, and complementary method to obtain 2-substituted homoallyl sulfonyl amides is described, starting from sulfonyl amides, aldehydes, and allyltrimethylsilane using iron(III) chloride as a sustainable catalyst. The scope of the process and the reactivity in aza-Prins cyclization is evaluated and supported by density functional theory (DFT) studies. Finally, an evaluation of the antiproliferative activity for this family of sulfonyl amides is also included.Grants (PGC2018-392094503-B-C22, CTQ2016-78205-P, and PID2019-106184GB-393-I00) funded by MCIN/AEI/ 10.13039/501100011033 and, as appropriate, by “ERDF A way of making Europe”, by the “European Union” or by the “European Union NextGenerationEU/PRTR”. V.S.M. thanks the Spanish MCIU for an FPU fellowship. D.A.C. thanks the Cabildo de Tenerife for a postdoctoral transfer contract and a Tenerife 2030 Programme (TF INNOVA 2016-2021) contract supported by the Marco Estratégico de Desarrollo Insular (MEDI) and Fondo de Desarrollo de Canarias (FDCAN). The text was revised by G. Jones, funded by the Cabildo de Tenerife from the same source under the same programme. I.F. is grateful for financial support from the Spanish MCIN/AEI/10.13039/501100011033 (Grants PID2019-106184GB-I00 and RED2018-102387-T).Peer reviewe

Ružička days : International conference 19th Ružička Days “Today Science – Tomorrow Industry” : Proceedings

Dear colleagues, we are extremely honoured to present to you the Proceedings of the international conference 19th Ružička Days, which was successfully held on September 21–23, 2022, in Vukovar, Croatia, in the hometown town of our famous Croatian scientist and first Nobel laureate, professor Leopold (Lavoslav) Ružička. The main goals of the Conference were to promote excellence, originality and innovation of interdisciplinary scientific research as well as the practical application of the obtained results through collaboration with industry, emphasizing thus the recognizable slogan of the Ružička Days conference: "Today Science – Tomorrow Industry". In addition, the Conference gave the opportunity for meetings, exchanging the ideas, opinions, experiences and cooperation among participants from different working surroundings. It is also important to point out that since 2008, within the international conference Ružička Days, Meeting of Young Chemists has also been held, where high school students, with the help of their mentors, present papers in the field of chemistry, with the aim to direct students and young people to the technical and natural sciences, especially chemistry. In its seventh issue (2011, 2013, 2015, 2017, 2019, 2021) the Proceedings publishes scientific and professional full papers of high quality in the following sections: Chemical analysis and synthesis (10), Chemical and biochemical engineering (3), Food technology and biotechnology (4), Chemistry in agriculture and forestry (1), Environmental protection (9) and 8th Meeting of Young Chemists (3). Full-length papers were subjected to an international review procedure done by eminent experts from the corresponding fields, to whom we express our gratitude, but they were not subjected to linguistic proofreading. On behalf of the Scientific and Organizing Committee of the 19th Ružička Days we cordially thank all the authors, reviewers, participants, lecturers, organizers, especially the international organizers EuCheMS and EHEDG, auspices and sponsors, and all the others who, in any way, supported the Conference and contributed to the preparation of the Proceedings, especially to our highly skilled and committed associates, who have put a lot of effort in the preparation of these Proceedings. At the very end, special thanks to our young, future scientists and their mentors who are faithful participants of the Meeting of Young Chemists of the Ružička Days conference. Enjoy the extremely interesting scientific and professional papers contained in these Proceedings, until the next 20th jubilee of Ružička Days in 2024! We are looking forward to meeting you again in Vukovar! Yours sincerely, Chief Editors Jurislav Babić Vesna Ocelić Bulatović Dajana Kučić Grgi