804 research outputs found
Unsolicited written narratives as a methodological genre in terminal illness: challenges and limitations
Stories about illness have proven invaluable in helping health professionals understand illness experiences. Such narratives have traditionally been solicited by researchers through interviews and the collection of personal writings, including diaries. These approaches are, however, researcher driven; the impetus for the creation of the story comes from the researcher and not the narrator. In recent years there has been exponential growth in illness narratives created by individuals, of their own volition, and made available for others to read in print or as Internet accounts. We sought to determine whether it was possible to identify such material for use as research data to explore the subject of living with the terminal illness amyotrophic lateral sclerosis/motor neuron disease—the contention being that these accounts are narrator driven and therefore focus on issues of greatest importance to the affected person. We encountered and sought to overcome a number of methodological and ethical challenges, which is our focus here
Designing Blockchain based services
Distributed Ledgers or Blockchain-based systems have the potential to provide enablers for the development of future services. By combining deep encryption, tamper-proof transparency and secure personal data to a wide variety of services, there are great opportunities for the development of new services.
In developing new service experiences that capitalise on the potential benefits of Blockchain, there are a number of key challenges. These include:
Emerging opportunities for services provided by blockchain
Blockchain as an Identity Enabler
Public perceptions and confusion about blockchain
Issues of privacy, mistrust of data storage and possible leakage
Design methodologies for services to guide users through new blockchain automated and
frictionless experiences
This short practice-based paper presents a case study and reflects on the learnings and experience of designing services utilising blockchain technology for digital identity. The paper identifies issues and problems and provides a comprehensive review of the benefits to establish a framework for designing services around distributed ledger blockchain based services
Designing Blockchain enabled customer experiences for new digital services
This practice-based paper presents a case study of designing services utilising blockchain technology. Blockchain provides
an extremely secure record of transactions and has the potential to simplify and automate many complex processes. In
this example Blockchain is used to validate a person’s identity through a digital passport. In using Blockchain the
customer journey becomes highly automated and has no points of user interaction, which user-research revealed has
both benefits and disadvantages. The paper discusses the challenges and opportunities of highly automated processes
and proposes a framework of design principles to be used when developing Blockchain and technology-based services
that produce invisible processes
Fungal proteins with mannanase activity identified directly from a Congo Red stained zymogram by mass spectrometry
Secreted fungal proteins with mannanase activity were identified by mass spectrometry of bands excised from a Congo Red stained zymogram containing locust bean gum as substrate. This technique circumvents the need to locate corresponding bands on a parallel gel without substrate and provides good accuracy in targeting proteins for identification. © 2009 Elsevier B.V. All rights reserved
What Affects Engagement in an Educational Online Community? Investigating a Blended Learning Course for Primary School Teachers Undertaking Postgraduate Professional Development
articipating in e-learning communities is a valuable way of enhancing teachers’ professional development (PD). However, teachers’ engagement with asynchronous online platforms can be affected by feelings of anxiety, a perceived lack of connection to others and technology issues. The purpose of this study was to investigate the factors that affect students’ engagement with e-learning communities through asynchronous Blackboard Discussion Boards (BBDBs) in a blended PD course for primary school teachers. Using a case study approach produced rich data through the use of focus groups and interviews to explore students’ and tutors’ perceptions of the BBDBs, and their preferences for online and face-to-face learning.
The overall finding revealed that participants’ engagement with online communities is affected by several interrelated factors, some of which distinctly relate to being human (i.e. emotions, relationships, power relations, agency, prior experiences and personality), whilst other factors relate to the usability of technology. These factors influenced the participants’ engagement with both the BBDBs and other online platforms. Additionally, this research identified that students created e-learning communities using social media platforms, which were a valuable source of professional, academic and personal support. This thesis contributes to the pedagogy and theory of e-learning communities through identifying several crucial elements which support the conditions required for people to make meaning with others through online communication. Through conceptualising online communication as a social literacy practice and closely examining how students experience the practices of face-to-face and online communication, this research extends the Literacies for Learning in Further Education framework, offering a contribution to the field of social literacy studies. Furthermore, through discovering that several complex interrelated human responses impact on people’s entanglement with others through online platforms, this thesis offers a contribution to the growing body of literature on posthumanism in digital education. These conclusions may be useful to educators who are designing online or blended learning courses in terms of understanding the factors that are crucial for meaningful engagement and learning
Inverse-kinematics one-neutron pickup with fast rare-isotope beams
New measurements and reaction model calculations are reported for single
neutron pickup reactions onto a fast \nuc{22}{Mg} secondary beam at 84 MeV per
nucleon. Measurements were made on both carbon and beryllium targets, having
very different structures, allowing a first investigation of the likely nature
of the pickup reaction mechanism. The measurements involve thick reaction
targets and -ray spectroscopy of the projectile-like reaction residue
for final-state resolution, that permit experiments with low incident beam
rates compared to traditional low-energy transfer reactions. From measured
longitudinal momentum distributions we show that the \nuc{12}{C}
(\nuc{22}{Mg},\nuc{23}{Mg}+\gamma)X reaction largely proceeds as a direct
two-body reaction, the neutron transfer producing bound \nuc{11}{C} target
residues. The corresponding reaction on the \nuc{9}{Be} target seems to largely
leave the \nuc{8}{Be} residual nucleus unbound at excitation energies high in
the continuum. We discuss the possible use of such fast-beam one-neutron pickup
reactions to track single-particle strength in exotic nuclei, and also their
expected sensitivity to neutron high- (intruder) states which are often
direct indicators of shell evolution and the disappearance of magic numbers in
the exotic regime.Comment: 8 pages, 5 figure
Trials and tribulations: understanding motivations for clinical research participation amongst adults with cystic fibrosis
In the context of understanding motivations for clinical research participation, many authors consider issues such as informed consent and how patients perceive the research method and process. However, many investigations focus only on one method of research, most commonly the randomised controlled trial. Understanding how chronically ill members of one specific patient group respond to all requests for research participation are rare. Cystic fibrosis (CF), a genetic condition whereby those affected are used to taking a wide array of treatments and attending a specialist care centre over many years, and are generally knowledgeable about their condition, represents an ideal case for investigating how staff requests for clinical research participation are accepted or declined. Using Bloor's systems of relevance framework for risk behaviour and risk reduction, specialist CF centre patients' motivations for participation or non-participation in clinical research can be understood. The framework takes into account two sets of conceptual oppositions: habituation and calculation, constraint and volition. These oppositions represent a range along a continuum of risk behaviour rather than being absolute distinctions. Decisions to participate are influenced mainly by the patient's state of health at the time of request, the nature of the trial and the social context within which sufferers are placed. Understanding why chronically ill patients refuse some requests and yet accept others may assist researchers in designing protocols that take these factors into account and achieve the desired numbers of participants whilst protecting those in vulnerable positions. © 2005 Elsevier Ltd. All rights reserved
Spectroscopy of neutron-unbound F
The ground state of F has been observed as an unbound resonance
keV above the ground state of F. Comparison of this
result with USDA/USDB shell model predictions leads to the conclusion that the
F ground state is primarily dominated by -shell configurations. Here
we present a detailed report on the experiment in which the ground state
resonance of F was first observed. Additionally, we report the first
observation of a neutron-unbound excited state in F at an excitation
energy of keV.Comment: 10 pages, 11 figures, Accepted for publication in Phys. Rev.
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