167 research outputs found

    Recovery of low-carbon ferrochrome with multi-component aluminum-silicon-chrome (Al - Si - Cr) alloy

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    The paper describes pilot smelting of low-carbon ferrochrome (LCFC) with new type of reductant – multi-component aluminum-silicon-chrome alloy (FASCh). Provisional calculations confirmed by results of pilot smelting show that use of FASCh alloy helps to stabilize LCFC slag and prevent its decomposition. Due to high Al content in FASCh the phase area of slag shifts from dicalcium silicate (larnite- Са2SiO4) area into the helenite area (2 CaO ∙ Al2O3 ∙ SiO2)

    A protocol for co-creating research project lay summaries with stakeholders:Guideline development for Canada's AGE-WELL Network

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    Background Funding bodies increasingly require researchers to write lay summaries to communicate projects’ real-world relevance to the public in an accessible way. However, research proposals and findings are generally not easily readable or understandable by non-specialist readers. Many researchers find writing lay summaries difficult because they typically write for fellow subject specialists or academics rather than the general public or a non-specialist audience. The primary objective of our project is to develop guidelines for researchers in Canada’s AGE-WELL Network of Centres of Excellence, and ultimately various other disciplines, sectors, and institutions, to co-create lay summaries of research projects with stakeholders. To begin, we produced a protocol for co-creating a lay summary based on workshops we organized and facilitated for an AGE-WELL researcher. This paper presents the lay summary co-creation protocol that AGE-WELL researchers will be invited to use. Methods Eligible participants in this project will be 24 AgeTech project researchers who are funded by the AGE-WELL network in its Core Research Program 2020. If they agree to participate in this project, we will invite them to use our protocol to co-produce a lay summary of their respective projects with stakeholders. The protocol comprises six steps: Investigate principles of writing a good lay summary, identify the target readership, identify stakeholders to collaborate with, recruit the identified stakeholders to work on a lay summary, prepare for workshop sessions, and execute the sessions. To help participants through the process, we will provide them with a guide to developing an accessible, readable research lay summary, help them make decisions, and host, and facilitate if needed, their lay summary co-creation workshops. Discussion Public-facing research outputs, including lay summaries, are increasingly important knowledge translation strategies to promote the impact of research on real-world issues. To produce lay summaries that include information that will interest a non-specialist readership and that are written in accessible language, stakeholder engagement is key. Furthermore, both researchers and stakeholders benefit by participating in the co-creation process. We hope the protocol helps researchers collaborate with stakeholders effectively to co-produce lay summaries that meet the needs of both the public and project funders

    Primjena frakcijske plinske analize za određivanje sadržaja oksidnih i dušičnih faza u ALNICO legurama

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    Fractional gas analysis procedure for estimating the contents of oxide and nitride inclusions in Alnico alloys produced from wastes of production is developed. The effect of the temperature and time of melt holding before pouring on the content of impurity oxide and nitride inclusions is considered. The content of SiO2 inclusions in Alnico mainly depends on the holding time before pouring and decreases with increasing holding time, whereas the content of Al2O3 inclusions decreases with increasing both temperature and time of holding. The content of TiN inclusions decreases with increasing holding time. As the holding temperature increases, the content of nitride inclusions decreases only with increasing holding time.Razrađena je metoda frakcijske plinske analize za vrednovanje oksidnih i dušičnih uključaka u ALNICO legurama, dobijenih iz gospodarskih otpada. Posmatran je utjecaj temperature i vremena zadržavanja kupke prije lijevanja. Sadržaj uključaka SiO2 uglavnom ovisi od vremena zadrške prije lijevanja i snižava se povećanjem tog vremena, istodobno se sadržaj uključaka Al2O3 smanjuje s povećavanjem i temperature i vremena zadrške. Sadržaj uključaka TiN smanjuje se povećavanjem vremena zadrške. S povećanjem temperature sadržaj dušičnih uključaka smanjuje se samo pri povećanju vremena zadrške prije lijevanja

    Clinical value of definition of an expression of molecule CD68 + cells inflammatory infiltration in biopsy gums at patients with gingivitis and periodontitis at treatment stages

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    In article changes of a clinical condition of periodontium tissue, degrees of expressiveness inflammatory infiltration in biopsy gums of 53 patients with gingivitis and periodontitis are analyzed. Immunophentyping cells of inflammatory infiltration in biopsy gums of patients, has revealed system cells mononuclear phagocytes (CD68 +) in a slight stages inflammatory changes that is a morphological substratum of possible relapse of an inflammation in periodontium.В статье анализируются изменения клинического состояния тканей пародонта, степени выраженности воспалительного инфильтрата в биоптатах десны 53 больных гингивитом и пародонтитом. Иммунофенотипирование клеток воспалительного инфильтрата в биоптатах десны пациентов, выявило клетки системы мононуклеарных фагоцитов (CD68+) в стадию слабовыраженных воспалительных изменений, что является морфологическим субстратом возможного рецидива воспаления в пародонте

    AUG_hairpin: prediction of a downstream secondary structure influencing the recognition of a translation start site

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    <p>Abstract</p> <p>Background</p> <p>The translation start site plays an important role in the control of translation efficiency of eukaryotic mRNAs. The recognition of the start AUG codon by eukaryotic ribosomes is considered to depend on its nucleotide context. However, the fraction of eukaryotic mRNAs with the start codon in a suboptimal context is relatively large. It may be expected that mRNA should possess some features providing efficient translation, including the proper recognition of a translation start site. It has been experimentally shown that a downstream hairpin located in certain positions with respect to start codon can compensate in part for the suboptimal AUG context and also increases translation from non-AUG initiation codons. Prediction of such a compensatory hairpin may be useful in the evaluation of eukaryotic mRNA translation properties.</p> <p>Results</p> <p>We evaluated interdependency between the start codon context and mRNA secondary structure at the CDS beginning: it was found that a suboptimal start codon context significantly correlated with higher base pairing probabilities at positions 13 – 17 of CDS of human and mouse mRNAs. It is likely that the downstream hairpins are used to enhance translation of some mammalian mRNAs <it>in vivo</it>. Thus, we have developed a tool, <it>AUG_hairpin</it>, to predict local stem-loop structures located within the defined region at the beginning of mRNA coding part. The implemented algorithm is based on the available published experimental data on the CDS-located stem-loop structures influencing the recognition of upstream start codons.</p> <p>Conclusion</p> <p>An occurrence of a potential secondary structure downstream of start AUG codon in a suboptimal context (or downstream of a potential non-AUG start codon) may provide researchers with a testable assumption on the presence of additional regulatory signal influencing mRNA translation initiation rate and the start codon choice. <it>AUG_hairpin</it>, which has a convenient Web-interface with adjustable parameters, will make such an evaluation easy and efficient.</p

    Status of ART-XC/SRG Instrument

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    Spectrum Roentgen Gamma (SRG) is an X-ray astrophysical observatory, developed by Russia in collaboration with Germany. The mission will be launched in March 2016 from Baikonur, by a Zenit rocket with a Fregat booster and placed in a 6-month-period halo orbit around L2. The scientific payload consists of two independent telescopes - a soft-x-ray survey instrument, eROSITA, being provided by Germany and a medium-x-ray-energy survey instrument ART-XC being developed by Russia. ART-XC will consist of seven independent, but co-aligned, telescope modules. The NASA Marshall Space Flight Center (MSFC) is fabricating the flight mirror modules for the ART-XC/SRG. Each mirror module will be aligned with a focal plane CdTe double-sided strip detectors which will operate over the energy range of 6-30 keV, with an angular resolution of less than 1, a field of view of approximately 34 and an expected energy resolution of about 10 percent at 14 keV

    Temperature, recreational fishing and diapause egg connections : dispersal of spiny water fleas (Bythotrephes longimanus)

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    © The Author(s), 2011. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License. The definitive version was published in Biological Invasions 13 (2011): 2513-2531, doi:10.1007/s10530-011-0078-8.The spiny water flea (Bythotrephes longimanus) is spreading from Great Lakes coastal waters into northern inland lakes within a northern temperature-defined latitudinal band. Colonization of Great Lakes coastal embayments is assisted by winds and seiche surges, yet rapid inland expansion across the northern states comes through an overland process. The lack of invasions at Isle Royale National Park contrasts with rapid expansion on the nearby Keweenaw Peninsula. Both regions have comparable geology, lake density, and fauna, but differ in recreational fishing boat access, visitation, and containment measures. Tail spines protect Bythotrephes against young of the year, but not larger fish, yet the unusual thick-shelled diapausing eggs can pass through fish guts in viable condition. Sediment traps illustrate how fish spread diapausing eggs across lakes in fecal pellets. Trillions of diapausing eggs are produced per year in Lake Michigan and billions per year in Lake Michigamme, a large inland lake. Dispersal by recreational fishing is linked to use of baitfish, diapausing eggs defecated into live wells and bait buckets, and Bythothephes snagged on fishing line, anchor ropes, and minnow seines. Relatively simple measures, such as on-site rinsing of live wells, restricting transfer of certain baitfish species, or holding baitfish for 24 h (defecation period), should greatly reduce dispersal.Study of Lakes Superior and Michigan was funded from NSF OCE-9726680 and OCE-9712872 to W.C.K., OCE-9712889 to J. Churchill. Geographic survey sampling and Park studies in the national parks during 2008-2010 were funded by a grant from the National Park Service Natural Resource Preservation Program GLNF CESU Task Agreement No. J6067080012

    The ART-XC Instrument on Board the SRG Mission

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    Spectrum Roentgen Gamma (SRG) is an X-ray astrophysical observatory, developed by Russia in collaboration with Germany. The mission will be launched in 2014 from Baikonur, by a Zenit rocket with a Fregat booster and placed in a 6-month-period halo orbit around L2. The scientific payload consists of two independent telescopes . a soft-x-ray survey instrument, eROSITA, being provided by Germany and a medium-x-ray-energy survey instrument ART-XC being developed by Russia. ART-XC will consist of seven independent, but co-aligned, telescope modules with seven corresponding cadmium-telluride focal plane detectors. Each will operate over the approximate energy range of 6- 30 keV, with an angular resolution of <1 ', a field of view of ~30 ' and an energy resolution about 10% at 14 keV. The NASA Marshall Space Flight Center (MSFC) will fabricate some of the mirror modules, to complement others fabricated by VNIIEF in Russia

    Propagule Pressure: A Null Model for Biological Invasions

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    null model, propagule pressure Invasion ecology has been criticised for its lack of general principles. To explore this criticism, we con-ducted a meta-analysis that examined characteristics of invasiveness (i.e. the ability of species to establish in, spread to, or become abundant in novel communities) and invasibility (i.e. the susceptibility of habitats to the establishment or proliferation of invaders). There were few consistencies among invasiveness char-acteristics (3 of 13): established and abundant invaders generally occupy similar habitats as native species, while abundant species tend to be less affected by enemies; germination success and reproductive output were significantly positively associated with invasiveness when results from both stages (establishment/ spread and abundance/impact) were combined. Two of six invasibility characteristics were also significant: communities experiencing more disturbance and with higher resource availability sustained greater establishment and proliferation of invaders. We also found that even though ‘propagule pressure ’ was considered in only 29 % of studies, it was a significant predictor of both invasiveness and invasibility (55 of 64 total cases). Given that nonindigenous species are likely introduced non-randomly, we contend that ‘propagule biases ’ may confound current paradigms in invasion ecology. Examples of patterns that could be confounded by propagule biases include characteristics of good invaders and susceptible habitats, release from enemies, evolution of ‘invasiveness’, and invasional meltdown. We conclude that propagule pressure should serve as the basis of a null model for studies of biological invasions when inferring process from patterns of invasion
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