20 research outputs found
Report for NMDGF Permit: 5, Letter to Mr. Gaylord on exceeding the limit
Document from New Mexico Department of Game & Fish Commercial permit
Triad representation of the Chern-Simons state in quantum gravity
We investigate a triad representation of the Chern-Simons state of quantum
gravity with a non-vanishing cosmological constant. It is shown that the
Chern-Simons state, which is a well-known exact wavefunctional within the
Ashtekar theory, can be transformed to the real triad representation by means
of a suitably generalized Fourier transformation, yielding a complex integral
representation for the corresponding state in the triad variables. It is found
that topologically inequivalent choices for the complex integration contour
give rise to linearly independent wavefunctionals in the triad representation,
which all arise from the one Chern-Simons state in the Ashtekar variables. For
a suitable choice of the normalization factor, these states turn out to be
gauge-invariant under arbitrary, even topologically non-trivial
gauge-transformations. Explicit analytical expressions for the wavefunctionals
in the triad representation can be obtained in several interesting asymptotic
parameter regimes, and the associated semiclassical 4-geometries are discussed.
In restriction to Bianchi-type homogeneous 3-metrics, we compare our results
with earlier discussions of homogeneous cosmological models. Moreover, we
define an inner product on the Hilbert space of quantum gravity, and choose a
natural gauge-condition fixing the time-gauge. With respect to this particular
inner product, the Chern-Simons state of quantum gravity turns out to be a
non-normalizable wavefunctional.Comment: Latex, 30 pages, 1 figure, to appear in Phys. Rev.
Validation of a 40-Gene Expression Profile Test to Predict Metastatic Risk in Localized High-Risk Cutaneous Squamous Cell Carcinoma
Background: Current staging systems for cutaneous squamous cell carcinoma (cSCC) have limited positive predictive value (PPV) for identifying patients who will experience metastasis.
Objective: To develop and validate a gene expression profile (GEP) test for predicting risk for metastasis in localized, high-risk cSCC with the goal of improving risk-directed patient management. Methods: Archival formalin-fixed paraffin-embedded primary cSCC tissue and clinicopathologic data (n=586) were collected from 23 independent centers in a prospectively designed study. A GEP signature was developed using a discovery cohort (n=202) and validated in a separate, non-overlaping, independent cohort (n=324). Results: A prognostic, 40-gene expression profile (40-GEP) test was developed and validated, stratifying high-risk cSCC patients into classes based on metastasis risk: Class 1 (low-risk), Class 2A (high-risk), and Class 2B (highest-risk). For the validation cohort, 3-year metastasis-free survival (MFS) rates were 91.4%, 80.6%, and 44.0%, respectively. A PPV of 60% was achieved for the highest-risk group (Class 2B), an improvement over staging systems; while negative predictive value, sensitivity, and specificity were comparable to staging systems. Limitations: Potential understaging of cases could affect metastasis rate accuracy.Conclusion: The 40-GEP test is an independent predictor of metastatic risk that can complement current staging systems for patients with high-risk cSCC
Recommended from our members
Game of Slugs
By Fighting Weasels studiosThursday Section: 8 to 10pmSection Leader: Peter MawhorterTeam Members: Cooper Smith & Robert GriegoGame of Slugs is a unique game that offers a satirical look into the typical freshman experience, featuring UC Santa Cruz. The incoming students will experiencea wide variety of amusing and stressful situations based off stories and experience from college students this game was modeled after. These include: signing upfor classes, avoiding marketers, activists and fraternities, finding food at the dining halls, being sexiled form your dorm room, and trudging to an early-morningclass. Class Chaos requires reaction-timing point-and-click gameplay in order to successfully sign up for all of the desired classes.Worry Plaza resembles Pac Mangame as the player uses the arrow keys to move and collect objects while avoiding the annoying marketers and promoters constantly trying to talk to the player andmake them late for class. Dining Hall Panic requires players to select from a variety of food choices in order to create a meal that is somehow both tasty and healthy.Locked Out has a pattern-repetition mechanic that requires players to watch, remember, and replicate the necessary knocking pattern to get their roommates attention.The 8:00 am uses the arrow keys and a gameplay mechanic resembling that of Dance Dance Revolution in order to keep the very sleepy character steady and walking as heheads off to his morning class
Recommended from our members
Game of Slugs
By Fighting Weasels studiosThursday Section: 8 to 10pmSection Leader: Peter MawhorterTeam Members: Cooper Smith & Robert GriegoGame of Slugs is a unique game that offers a satirical look into the typical freshman experience, featuring UC Santa Cruz. The incoming students will experiencea wide variety of amusing and stressful situations based off stories and experience from college students this game was modeled after. These include: signing upfor classes, avoiding marketers, activists and fraternities, finding food at the dining halls, being sexiled form your dorm room, and trudging to an early-morningclass. Class Chaos requires reaction-timing point-and-click gameplay in order to successfully sign up for all of the desired classes.Worry Plaza resembles Pac Mangame as the player uses the arrow keys to move and collect objects while avoiding the annoying marketers and promoters constantly trying to talk to the player andmake them late for class. Dining Hall Panic requires players to select from a variety of food choices in order to create a meal that is somehow both tasty and healthy.Locked Out has a pattern-repetition mechanic that requires players to watch, remember, and replicate the necessary knocking pattern to get their roommates attention.The 8:00 am uses the arrow keys and a gameplay mechanic resembling that of Dance Dance Revolution in order to keep the very sleepy character steady and walking as heheads off to his morning class
Facilitation of Relational Learning in Schizophrenia
behavioral sciences ISSN 2076-328X www.mdpi.com/journal/behavsc