A pilot study of a problem-solving method of teaching.

Thesis (M.S.)--Boston Universit

A pilot study of a problem-solving method of teaching.

Thesis (M.S.)--Boston Universit

Bone cylinders, discs and terminals-scroll holders from roman funerary deposits?

Elementos completos y fragmentados de objetos de hueso compuestos y de manufactura cuidada han sido documentados en contextos de época romana en la zona Noroeste de Europa; nuestro trabajo sugiere que estas formas pertenencen primeramente a la segunda mitad del II y comienzos del III siglo. Los investigadores han descrito diferentes posibles funciones para estos objetos, pero ninguna ha sido hasta la fecha satisfactoria. El conjunto analizado consiste en varios elementos de hueso torneado —dos cilindros conectados, en cuyos sendos extremos se observa un disco y un pequeño pomo o terminal. Este artículo considera un pequeño número de elementos completos recuperados como elementos funerarios secundarios y emplea esta evidencia para interpretar un conjunto mayor de items incompletos, a veces también procedentes de sepulturas como ofrendas secundarias, pero mayormente recuperadas como restos de la pira funeraria. Interpretaciones previas de su uso han sido rechazadas a favour de su identificación como sujeta rollos de papiro.Complete and fragmentary elements of well made, composite, bone objects have been excavated in funerary contexts from the Roman period in North-western Europe; our work suggests that these forms belong primarily to the mid second and earlier third centuries. Researchers have described different possible functions of these objects, but to date none have been entirely satisfactory. The assemblage consists of several lathe-turned bone elements —two connected cylinders, and on both ends a disc and small knob or terminal. This paper considers the small number of complete assemblages recovered as secondary grave goods and uses this evidence to interpret a wider range of similar but incomplete finds, sometimes also placed in graves as secondary grave goods, but mainly recovered as primary, pyre debris. Previous interpretations of their use are rejected in favour of an identification as papyri scroll holders

Response of Siratro (Macroptilium atropurpureum Urb. Rabaceae) to Vesicular-arbuscular Mycorrhizal Fungi and Rhizobium sp. in Sterilized Soil

The effect of inoculation of six species of vesicular-arbuscular mycorrhizal fungi viz., Gigaspora margarita, Glomus mosseae, G. monosporum, G. versiformis, G. fasciculatum, G. deserticola and Rhizobium sp. on growth and NPK content in siratro (Macroptilium atropurpureum) was studied. The mycorrhizal species were isolated from the rhizosphere forest soils of the Western Ghats and multiplied in pot culture with Sorghum bicolor as the host plant. Rhizobium sp. isolated from fresh nodules of siratro was cultured and maintained in yeast extract mannitol broth. The influence of VAM fungi and Rhizobium sp. either singly or in combination on growth and nutrient contents of siratro showed statistically significant increase after only 60 days of plant growth. Dual inoculation with VAM fungi and Rhizobium increased plant nodule number and tissue NPK content. Highest growth and nutrient content were exhibited by plants inoculated with Rhizobium together with multiple VAM fungi

Specific binding of luteinizing hormone to leydig tumor cells

A radioimmunoassay was used to detect luteinizing hormone (LH) bound to washed Leydig tumor cells. Tumor cell suspensions were incubated with LH at 37° and washed repeatedly by centrifugation with isotonic 0.9% NaCl solution. The tumor cells contained large quantities of LH even after they were washed sufficiently to produce a 106-fold dilution of unbound LH. Six washings (106-fold dilution) were no more effective in removing LH from the cells than three washings (103-fold dilution). Binding was not influenced by the temperature at which the cells were washed. The extent of LH binding was related to the number of cells, with approximately 5300 ± 960 molecules of LH bound per cell. LH binding was also proportional to the same concentrations of LH which produced a steroidogenic dose response curve. The binding constant of 1.5 × 10-8 m was considered to be higher than that expected for nontumorous tissues. Tumor cells bound more LH than did erythrocytes or thymocytes under the same conditions

Cessation of steroidogenesis in leydig cell tumors after removal of luteinizing hormone and adenosine cyclic 3',5'-monophosphate

Luteinizing hormone (LH), but not follicle-stimulating hormone or prolactin, was shown to enhance steroid synthesis of Leydig tumor cells in vitro. Adenosine cyclic 3',5'-monophosphate (cAMP) duplicated the effect of LH. Removal of LH from the medium within 1 hour of incubation by washing the cells had no effect on the rate of steroid synthesis previously stimulated by LH. Under these conditions, addition of LH antiserum was required to reduce steroid synthesis. In contrast, removal of cAMP by washing the tumor cells caused a rapid termination of the previously induced steroidogenesis. Cycloheximide reduced the steroid synthesis initiated by LH. These results suggest that (a) steroidogenesis may be controlled by short lived factors (proteins), (b) LH may be required continually to elevate cAMP levels to maintain steroid synthesis at stimulated rates, and (c) that LH is probably bound to the tumor cells

Experimental simulation of gestational changes in the vagina of the mouse

No Abstract.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/50244/1/1050730108_ftp.pd

Bone loss and the aromatase inhibitors

The increasing use of systemic adjuvant therapies has considerably improved the prognosis from early breast cancer. However, some of these therapies affect bone metabolism, resulting in osteoporosis. Aromatase inhibitors lower circulating oestrogen levels to almost unrecordable levels in postmenopausal women, predisposing them to bone loss with an increase in fracture risk. Ongoing clinical trials are favouring the use of the aromatase inhibitors over tamoxifen and this may advocate greater use of these drugs in the future. Strategies for the identification and management of treatment-induced bone loss are currently being defined