2,430 research outputs found
Backpack VLBI terminal with subscentimeter capability
Backpack portable equipment was developed to measure vector baseline from approximately 1 km to 100 km in length with subcentimeter to few centimeter accuracy. The equipment design features as well as the instrumentation specifications are discussed. It is shown that the unit has the following advantages: it is simple in concept; it is reliable in unattended operation; and it is inexpensive (less than $15,000 per unit)
Observation of magnetocoriolis waves in a liquid metal Taylor-Couette experiment
The first observation of fast and slow magnetocoriolis (MC) waves in a
laboratory experiment is reported. Rotating nonaxisymmetric modes arising from
a magnetized turbulent Taylor-Couette flow of liquid metal are identified as
the fast and slow MC waves by the dependence of the rotation frequency on the
applied field strength. The observed slow MC wave is damped but the observation
provides a means for predicting the onset of the Magnetorotational Instability
Vanishing viscosity limits for the degenerate lake equations with Navier boundary conditions
The paper is concerned with the vanishing viscosity limit of the
two-dimensional degenerate viscous lake equations when the Navier slip
conditions are prescribed on the impermeable boundary of a simply connected
bounded regular domain. When the initial vorticity is in the Lebesgue space
with , we show the degenerate viscous lake equations
possess a unique global solution and the solution converges to a corresponding
weak solution of the inviscid lake equations. In the special case when the
vorticity is in , an explicit convergence rate is obtained
Hydrodynamic and magnetohydrodynamic computations inside a rotating sphere
Numerical solutions of the incompressible magnetohydrodynamic (MHD) equations
are reported for the interior of a rotating, perfectly-conducting, rigid
spherical shell that is insulator-coated on the inside. A previously-reported
spectral method is used which relies on a Galerkin expansion in
Chandrasekhar-Kendall vector eigenfunctions of the curl. The new ingredient in
this set of computations is the rigid rotation of the sphere. After a few
purely hydrodynamic examples are sampled (spin down, Ekman pumping, inertial
waves), attention is focused on selective decay and the MHD dynamo problem. In
dynamo runs, prescribed mechanical forcing excites a persistent velocity field,
usually turbulent at modest Reynolds numbers, which in turn amplifies a small
seed magnetic field that is introduced. A wide variety of dynamo activity is
observed, all at unit magnetic Prandtl number. The code lacks the resolution to
probe high Reynolds numbers, but nevertheless interesting dynamo regimes turn
out to be plentiful in those parts of parameter space in which the code is
accurate. The key control parameters seem to be mechanical and magnetic
Reynolds numbers, the Rossby and Ekman numbers (which in our computations are
varied mostly by varying the rate of rotation of the sphere) and the amount of
mechanical helicity injected. Magnetic energy levels and magnetic dipole
behavior are exhibited which fluctuate strongly on a time scale of a few eddy
turnover times. These seem to stabilize as the rotation rate is increased until
the limit of the code resolution is reached.Comment: 26 pages, 17 figures, submitted to New Journal of Physic
Ariel - Volume 12(13) Number 2
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Coriolis force in Geophysics: an elementary introduction and examples
We show how Geophysics may illustrate and thus improve classical Mechanics
lectures concerning the study of Coriolis force effects. We are then interested
in atmospheric as well as oceanic phenomena we are familiar with, and are for
that reason of pedagogical and practical interest. Our aim is to model them in
a very simple way to bring out the physical phenomena that are involved.Comment: Accepted for publication in European Journal of Physic
Scaling and energy transfer in rotating turbulence
The inertial-range properties of quasi-stationary hydrodynamic turbulence
under solid-body rotation are studied via high-resolution direct numerical
simulations. For strong rotation the nonlinear energy cascade exhibits
depletion and a pronounced anisotropy with the energy flux proceeding mainly
perpendicularly to the rotation axis. This corresponds to a transition towards
a quasi-two-dimensional flow similar to a linear Taylor-Proudman state. In
contrast to the energy spectrum along the rotation axis which does not scale
self-similarly, the perpendicular spectrum displays an inertial range with
-behavior. A new phenomenology gives a rationale for the
observations. The scaling exponents of structure functions up to
order measured perpendicular to the rotation axis indicate reduced
intermittency with increasing rotation rate. The proposed phenomenology is
consistent with the inferred asymptotic non-intermittent behavior
.Comment: to be published in Europhysics Letters (www.epletters.net), minor
changes to match version in prin
Distinct expression pattern of the full set of secreted phospholipases A2 in human colorectal adenocarcinomas: sPLA2-III as a biomarker candidate
Recent studies suggest that secreted phospholipases A2 (sPLA2s) represent attractive potential tumour biomarkers and therapeutic targets for various cancers. As a first step to address this issue in human colorectal cancer, we examined the expression of the full set of sPLA2s in sporadic adenocarcinomas and normal matched mucosa from 21 patients by quantitative PCR and immunohistochemistry. In normal colon, PLA2G2A and PLA2G12A were expressed at high levels, PLA2G2D, PLA2G5, PLA2G10 and PLA2G12B at moderate levels, and PLA2G1B, PLA2G2F and PLA2G3 at low levels. In adenocarcinomas from left and right colon, the expression of PLA2G3 was increased by up to 40-fold, while that of PLA2G2D and PLA2G5 was decreased by up to 23- and 14-fold. The variations of expression for sPLA2-IID, sPLA2-III and sPLA2-V were confirmed at the protein level. The expression pattern of these sPLA2s appeared to be linked respectively to the overexpression of interleukin-8, defensin α6, survivin and matrilysin, and downregulation of SFRP-1 and RLPA-1, all these genes being associated to colon cancer. This original sPLA2 profile observed in adenocarcinomas highlights the potential role of certain sPLA2s in colon cancer and suggests that sPLA2-III might be a good candidate as a novel biomarker for both left and right colon cancers
Self Running Droplet: Emergence of Regular Motion from Nonequilibrium Noise
Spontaneous motion of an oil droplet driven by chemical nonequilibricity is
reported. It is shown that the droplet undergoes regular rhythmic motion under
appropriately designed boundary conditions, whereas it exhibits random motion
in an isotropic environment. This study is a novel manifestation on the direct
energy transformation of chemical energy into regular spatial-motion under
isothermal conditions. A simple mathematical equation including noise
reproduces the essential feature of the transition from irregularity into
periodic regular motion. Our results will inspire the theoretical study on the
mechanism of molecular motors in living matter, working under significant
influence of thermal fluctuation.Comment: 4 pages, 4 figure
Differential requirement for P2X7R function in IL-17 dependent vs. IL-17 independent cellular immune responses
IL17-dependent autoimmunity to collagen type V (Col V) has been associated with lung transplant obliterative bronchiolitis. Unlike the T helper 1 (Th1)-dependent immune responses to Tetanus Toxoid (TT), the Th17 response to Col V in lung transplant patients and its Th1/17 variant observed in coronary artery disease patients requires IL-1ÎČ, tumor necrosis factor α and CD14(+) cells. Given the involvement of the P2X7 receptor (P2X7R) in monocyte IL-1ÎČ responses, we investigated its role in Th17-, Th1/17- and Th1-mediated proinflammatory responses. Transfer of antigen-pulsed peripheral blood mononucleated cells (PBMCs) from Col V-reactive patients into SCID mouse footpads along with P2X7R antagonists revealed a selective inhibition of Col V-, but not TT-specific swelling responses. P2X7R inhibitors blocked IL-1ÎČ induction from monocytes, including both Col V-α1 peptide-induced (T-dependent), as well as native Col V-induced (T-independent) responses. Significantly higher P2X7R expression was found on CXCR3(neg) CCR4(+)/6(+) CD4(+) [Th17] versus CXCR3(+)CCR4/6(neg) CD4(+) [Th1] subsets in PBMCs, suggesting that the paradigm of selective dependence on P2X7R might extend beyond Col V autoimmunity. Indeed, P2X7R inhibitors suppressed not only anti-Col V, but also Th1/17-mediated alloimmunity, in a heart transplant patient without affecting anti-viral Epstein-Barr virus responses. These results suggest that agents targeting the P2X7R might effectively treat Th17-related transplant pathologies, while maintaining Th1-immunity to infection
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