Combined electrolysis device and fuel cell and method of operation Patent

Operation method for combined electrolysis device and fuel cell using molten salt to produce power by thermoelectric regeneration mechanis

The size and polydispersity of silica nanoparticles under simulated hot spring conditions

The nucleation and growth of silica nanoparticles in supersaturated geothermal waters was simulated using a flow-through geothermal simulator system. The effect of silica concentration ([SiO2]), ionic strength (IS), temperature (T) and organic additives on the size and polydispersity of the forming silica nanoparticles was quantified. A decrease in temperature (58 to 33°C) and the addition of glucose restricted particle growth to sizes <20 nm, while varying [SiO2] or ISdid not affect the size (30-35 nm) and polydispersity (±9 nm) observed at 58°C. Conversely, the addition of xanthan gum induced the development of thin films that enhanced silica aggregation

Query Expansion of Zero-Hit Subject Searches: Using a Thesaurus in Conjunction with NLP Techniques

The focus of our study is zero-hit queries in keyword subject searches and the effort of increasing recall in these cases by reformulating and, then, expanding the initial queries using an external source of knowledge, namely a thesaurus. To this end, the objectives of this study are twofold. First, we perform the mapping of query terms to the thesaurus terms. Second, we use the matched terms to expand the user’s initial query by taking advantage of the thesaurus relations and implementing natural language processing (NLP) techniques. We report on the overall procedure and elaborate on key points and considerations of each step of the process

Scattering by nonspherical systems

Scattering by nonspherical particles with size of order of wavelength - scattering by axisymmetric penetrable particles using approximate matching of boundary condition

Molecular determinants of drug-specific sensitivity for epidermal growth factor receptor (EGFR) exon 19 and 20 mutants in non-small cell lung cancer.

We hypothesized that aberrations activating epidermal growth factor receptor (EGFR) via dimerization would be more sensitive to anti-dimerization agents (e.g., cetuximab). EGFR exon 19 abnormalities (L747_A750del; deletes amino acids LREA) respond to reversible EGFR kinase inhibitors (TKIs). Exon 20 in-frame insertions and/or duplications (codons 767 to 774) and T790M mutations are clinically resistant to reversible/some irreversible TKIs. Their impact on protein function/therapeutic actionability are not fully elucidated.In our study, the index patient with non-small cell lung cancer (NSCLC) harbored EGFR D770_P772del_insKG (exon 20). A twenty patient trial (NSCLC cohort) (cetuximab-based regimen) included two participants with EGFR TKI-resistant mutations ((i) exon 20 D770>GY; and (ii) exon 19 LREA plus exon 20 T790M mutations). Structural modeling predicted that EGFR exon 20 anomalies (D770_P772del_insKG and D770>GY), but not T790M mutations, stabilize the active dimer configuration by increasing the interaction between the kinase domains, hence sensitizing to an agent preventing dimerization. Consistent with predictions, the two patients harboring D770_P772del_insKG and D770>GY, respectively, responded to an EGFR antibody (cetuximab)-based regimen; the T790M-bearing patient showed no response to cetuximab combined with erlotinib. In silico modeling merits investigation of its ability to optimize therapeutic selection based on structural/functional implications of different aberrations within the same gene

Tuning Nanocrystal Surface Depletion by Controlling Dopant Distribution as a Route Toward Enhanced Film Conductivity

Electron conduction through bare metal oxide nanocrystal (NC) films is hindered by surface depletion regions resulting from the presence of surface states. We control the radial dopant distribution in tin-doped indium oxide (ITO) NCs as a means to manipulate the NC depletion width. We find in films of ITO NCs of equal overall dopant concentration that those with dopant-enriched surfaces show decreased depletion width and increased conductivity. Variable temperature conductivity data shows electron localization length increases and associated depletion width decreases monotonically with increased density of dopants near the NC surface. We calculate band profiles for NCs of differing radial dopant distributions and, in agreement with variable temperature conductivity fits, find NCs with dopant-enriched surfaces have narrower depletion widths and longer localization lengths than those with dopant-enriched cores. Following amelioration of NC surface depletion by atomic layer deposition of alumina, all films of equal overall dopant concentration have similar conductivity. Variable temperature conductivity measurements on alumina-capped films indicate all films behave as granular metals. Herein, we conclude that dopant-enriched surfaces decrease the near-surface depletion region, which directly increases the electron localization length and conductivity of NC films

Low temperature, postgrowth self-doping of CdTe single crystals due to controlled deviation from stoichiometry

Careful analysis of the Cd-Te pressure-temperature-composition phase diagram, shows a deviation of CdTe stoichiometry only in the Te-depletion direction between 450 and 550 degrees C. Combined control over the semiconductor composition, via intrinsic defects, and over the atmosphere and cooling rate can, therefore, yield a process for intrinsic doping of CdTe at these relatively low temperatures. We present results that support this. Quenching of CdTe, following its annealing in Te atmosphere at 400-550 degrees C, leads to p-type conductivity with a hole concentration of similar to 2 x 10(16) cm(-3). Slow cooling of the samples, after 550 degrees C annealing in Te or in vacuum, increases the hole concentration by one order of magnitude, as compared to quenching at the same temperature. We explain this increase by the defect reaction between Te vacancies and Te interstitials. Annealing in Cd at 400-550 degrees C leads to n-type conductivity with an electron concentration of similar to 2 x 10(16) cm(-3). Annealing at 450-550 degrees C in the equilibrium atmosphere, provided by adding CdTe powder, gives n-type material

Modified Wandzura-Wilczek Relation with the Nachtmann Variable

If one retains M^2/Q^2 terms in the kinematics, the Nachtmann variable \xi seems to be more appropriate to describe deep inelastic lepton-nucleon scattering. Up to the first power of M^2/Q^2, a modified Wandzura-Wilczek relation with respect to \xi was derived. Kinematical correction factors are given as functions of \xi and Q^2. A comparison of the modified g_2^WW(\xi) and original g_2^WW(x) with the most recent g_2 data is shown.Comment: 10 pages, 3 figures, revised version with minor correction