13,241 research outputs found
Entanglement and statistics in Hong-Ou-Mandel interferometry
Hong-Ou-Mandel interferometry allows one to detect the presence of
entanglement in two-photon input states. The same result holds for
two-particles input states which obey to Fermionic statistics. In the latter
case however anti-bouncing introduces qualitative differences in the
interferometer response. This effect is analyzed in a Gedankenexperiment where
the particles entering the interferometer are assumed to belong to a
one-parameter family of quons which continuously interpolate between the
Bosonic and Fermionic statistics.Comment: 7 pages, 3 figures; minor editorial changes and new references adde
Non-Pauli Effects from Noncommutative Spacetimes
Noncommutative spacetimes lead to nonlocal quantum field theories (qft's)
where spin-statistics theorems cannot be proved. For this reason, and also
backed by detailed arguments, it has been suggested that they get corrected on
such spacetimes leading to small violations of the Pauli principle. In a recent
paper \cite{Pauli}, Pauli-forbidden transitions from spacetime noncommutativity
were calculated and confronted with experiments. Here we give details of the
computation missing from this paper. The latter was based on a spacetime
different from the Moyal plane. We argue that it
quantizes time in units of . Energy is then conserved only mod
. Issues related to superselection rules raised by non-Pauli
effects are also discussed in a preliminary manner.Comment: 15 Pages, 1 Table, Full details and further developments of
arXiv:1003.2250. This version is close to the one accepted by JHE
The stochastic limit in the analysis of the open BCS model
In this paper we show how the perturbative procedure known as {\em stochastic
limit} may be useful in the analysis of the Open BCS model discussed by Buffet
and Martin as a spin system interacting with a fermionic reservoir. In
particular we show how the same values of the critical temperature and of the
order parameters can be found with a significantly simpler approach
Molecular determinants of drug-specific sensitivity for epidermal growth factor receptor (EGFR) exon 19 and 20 mutants in non-small cell lung cancer.
We hypothesized that aberrations activating epidermal growth factor receptor (EGFR) via dimerization would be more sensitive to anti-dimerization agents (e.g., cetuximab). EGFR exon 19 abnormalities (L747_A750del; deletes amino acids LREA) respond to reversible EGFR kinase inhibitors (TKIs). Exon 20 in-frame insertions and/or duplications (codons 767 to 774) and T790M mutations are clinically resistant to reversible/some irreversible TKIs. Their impact on protein function/therapeutic actionability are not fully elucidated.In our study, the index patient with non-small cell lung cancer (NSCLC) harbored EGFR D770_P772del_insKG (exon 20). A twenty patient trial (NSCLC cohort) (cetuximab-based regimen) included two participants with EGFR TKI-resistant mutations ((i) exon 20 D770>GY; and (ii) exon 19 LREA plus exon 20 T790M mutations). Structural modeling predicted that EGFR exon 20 anomalies (D770_P772del_insKG and D770>GY), but not T790M mutations, stabilize the active dimer configuration by increasing the interaction between the kinase domains, hence sensitizing to an agent preventing dimerization. Consistent with predictions, the two patients harboring D770_P772del_insKG and D770>GY, respectively, responded to an EGFR antibody (cetuximab)-based regimen; the T790M-bearing patient showed no response to cetuximab combined with erlotinib. In silico modeling merits investigation of its ability to optimize therapeutic selection based on structural/functional implications of different aberrations within the same gene
A model of ballistic aggregation and fragmentation
A simple model of ballistic aggregation and fragmentation is proposed. The
model is characterized by two energy thresholds, Eagg and Efrag, which
demarcate different types of impacts: If the kinetic energy of the relative
motion of a colliding pair is smaller than Eagg or larger than Efrag, particles
respectively merge or break; otherwise they rebound. We assume that particles
are formed from monomers which cannot split any further and that in a
collision-induced fragmentation the larger particle splits into two fragments.
We start from the Boltzmann equation for the mass-velocity distribution
function and derive Smoluchowski-like equations for concentrations of particles
of different mass. We analyze these equations analytically, solve them
numerically and perform Monte Carlo simulations. When aggregation and
fragmentation energy thresholds do not depend on the masses of the colliding
particles, the model becomes analytically tractable. In this case we show the
emergence of the two types of behavior: the regime of unlimited cluster growth
arises when fragmentation is (relatively) weak and the relaxation towards a
steady state occurs when fragmentation prevails. In a model with mass-dependent
Eagg and Efrag the evolution with a cross-over from one of the regimes to
another has been detected
Spacelike Ricci Inheritance Vectors in a Model of String Cloud and String Fluid Stress Tensor
We study the consequences of the existence of spacelike Ricci inheritance
vectors (SpRIVs) parallel to for model of string cloud and string fluid
stress tensor in the context of general relativity. Necessary and sufficient
conditions are derived for a spacetime with a model of string cloud and string
fluid stress tensor to admit a SpRIV and a SpRIV which is also a spacelike
conformal Killing vector (SpCKV). Also, some results are obtained.Comment: 11 page
Modified Wandzura-Wilczek Relation with the Nachtmann Variable
If one retains M^2/Q^2 terms in the kinematics, the Nachtmann variable \xi
seems to be more appropriate to describe deep inelastic lepton-nucleon
scattering. Up to the first power of M^2/Q^2, a modified Wandzura-Wilczek
relation with respect to \xi was derived. Kinematical correction factors are
given as functions of \xi and Q^2. A comparison of the modified g_2^WW(\xi) and
original g_2^WW(x) with the most recent g_2 data is shown.Comment: 10 pages, 3 figures, revised version with minor correction
Conjugacy theorems for loop reductive group schemes and Lie algebras
The conjugacy of split Cartan subalgebras in the finite dimensional simple
case (Chevalley) and in the symmetrizable Kac-Moody case (Peterson-Kac) are
fundamental results of the theory of Lie algebras. Among the Kac-Moody Lie
algebras the affine algebras stand out. This paper deals with the problem of
conjugacy for a class of algebras --extended affine Lie algebras-- that are in
a precise sense higher nullity analogues of the affine algebras. Unlike the
methods used by Peterson-Kac, our approach is entirely cohomological and
geometric. It is deeply rooted on the theory of reductive group schemes
developed by Demazure and Grothendieck, and on the work of J. Tits on buildingsComment: Publi\'e dans Bulletin of Mathematical Sciences 4 (2014), 281-32
Search for exchange-antisymmetric two-photon states
Atomic two-photon J=0 J'=1 transitions are forbidden for
photons of the same energy. This selection rule is related to the fact that
photons obey Bose-Einstein statistics. We have searched for small violations of
this selection rule by studying transitions in atomic Ba. We set a limit on the
probability that photons are in exchange-antisymmetric states:
.Comment: 5 pages, 4 figures, ReVTeX and .eps. Submitted to Phys. Rev. Lett.
Revised version 9/25/9
Infrared receivers for low background astronomy: Incoherent detectors and coherent devices from one micrometer to one millimeter
The status of incoherent detectors and coherent receivers over the infrared wavelength range from one micrometer to one millimeter is described. General principles of infrared receivers are included, and photon detectors, bolometers, coherent receivers, and important supporting technologies are discussed, with emphasis on their suitability for low background astronomical applications. Broad recommendations are presented and specific opportunities are identified for development of improved devices
- …