NILDE in BESS: cosa ? cambiato e prospettive future

This paper presents the BESS project, its framework and growth, and the positive impact of NILDE on it.Il paper intende presentare la realt? di Bess, come ? nata e come si ? sviluppata in questi anni anche con l?introduzione di Nilde come metodo di lavoro e di servizio. La prima parte spiega come ? organizzata la struttura e quale ? stato il percorso di Bess, la seconda analizza l?evoluzione e la crescita dell?uso di Nilde all?interno del consorzio

Cataloghi: la sfida della concretezza

The Communication presents the activities of the Catalogs Group "Nilde Libraries Committee, the activities are focused on the national catalogs of libraries participating at the NILDE network. The survey launched in 2006 led to the identification of a significant number of libraries that were not included in any national catalog. Subsequently, a procedure was initiated in which these situations have been regularized and a specific policy has been issued. The members of the "Catalogs Group" contacted the individual responsible for the document delivery service providing assistance to overcome encountered problems. The direct involvement of libraries led to good results so that only 32 libraries (in June 2009) were not yet visible on national catalogs. Of crucial importance was the cooperation with ACNP, which become an active partner of NILDE, encouraging the spread of the Network. The monitoring allowed us to understand the variety of Nilde libraries, covering a wide range of disciplines, located throughout the country. The group is also activated as a result of reports received by the CBN or by the List Nilde-forni, also for what concern the visibility of the catalogs. The adoption of advanced tools for linking, such as SFX, provides a solution to connect their electronic resources and to allow better access to users. For the better management of document delivery would be useful to have a single connection point of an entire virtual library of institution or university. Finally, the importance of cataloging of Open Access journals to promote their visibility through inclusion in the ACNP catalogue and the still open issue of cataloging the electronic resources as with paper publications, are mentioned.La comunicazione presenta l\u27attivit? del "Gruppo cataloghi" del Comitato Biblioteche Nilde (CBN), incentrata sul monitoraggio dell\u27adesione ai cataloghi nazionali da parte delle biblioteche partecipanti al network NILDE. Il rilevamento ? stato avviato nel 2006 ed ha portato all\u27individuazione di un significativo numero di biblioteche che non risultavano in alcun catalogo nazionale. Successivamente sono state avviate le procedure per la regolarizzazione della loro situazione, pubblicando anche un apposito regolamento. I componenti del "Gruppo cataloghi" hanno contattato i singoli responsabili dei servizi di document delivery offrendo assistenza per superare i problemi riscontrati. Il coinvolgimento diretto delle biblioteche ha portato a buoni risultati tanto che al giugno 2009 solo 32 biblioteche non erano ancora visibili sui cataloghi nazionali. Fondamentale la collaborazione con ACNP, che ? diventato un partner attivo di NILDE, favorendone la diffusione. L\u27attivit? di monitoraggio ha permesso di comprendere la variet? di biblioteche Nilde che riunisce biblioteche distribuite su tutto il territorio nazionale, che coprono una ampia gamma di discipline. Il gruppo si ? anche attivato a seguito di segnalazioni di malfunzionamento che pervengono al CBN o alla lista Nilde-forni, anche per quanto riguarda la visibilit? dei cataloghi. L\u27adozione di strumenti avanzati di linking come SFX offre alle istituzioni una soluzione per collegare le loro risorse elettroniche e per consentire un migliore accesso agli utenti. Per la migliore gestione del document delivery sarebbe utile poter disporre di un unico indirizzo e-mail come punto di raccordo di una intera biblioteca virtuale elettronica di ente o di ateneo. Infine vengono citate: l\u27importanza di catalogazione dei periodici Open Access per favorirne la visibilit? grazie all\u27inserimento in ACNP e la problematica ancora aperta della catalogazione completa delle risorse elettroniche al pari di quanto ? avvenuto per i documenti su carta

Risk stratification of patients with SARS-CoV-2 by tissue factor expression in circulating extracellular vesicles

Inflammatory response following SARS-CoV-2 infection results in substantial increase of amounts of intravascular pro-coagulant extracellular vesicles (EVs) expressing tissue factor (CD142) on their surface. CD142-EV turned out to be useful as diagnostic biomarker in COVID-19 patients. Here we aimed at studying the prognostic capacity of CD142-EV in SARS-CoV-2 infection. Expression of CD142-EV was evaluated in 261 subjects admitted to hospital for pneumonia and with a positive molecular test for SARS-CoV-2. The study population consisted of a discovery cohort of selected patients (n = 60) and an independent validation cohort including unselected consecutive enrolled patients (n = 201). CD142-EV levels were correlated with post-hospitalization course of the disease and compared to the clinically available 4C Mortality Score as referral. CD142-EV showed a reliable performance to predict patient prognosis in the discovery cohort (AUC = 0.906) with an accuracy of 81.7%, that was confirmed in the validation cohort (AUC = 0.736). Kaplan-Meier curves highlighted a high discrimination power in unselected subjects with CD142-EV being able to stratify the majority of patients according to their prognosis. We obtained a comparable accuracy, being not inferior in terms of prediction of patients' prognosis and risk of mortality, with 4C Mortality Score. The expression of surface vesicular CD142 and its reliability as prognostic marker was technically validated using different immunocapture strategies and assays. The detection of CD142 on EV surface gains considerable interest as risk stratification tool to support clinical decision making in COVID-19

Strategies and Alliances into Action to Improve National Collaboration

The Italian NILDE network of libraries continues to grow through the use of the NILDE system and currently comprises more than 600 Italian librarians and about 10.000 registered end-users.The system allows to daily manage and to record all the Inter-Library-Loan (ILL) operations, with a high national coverage. This paper presents the NILDE network governance and evolution and the strategies that have been put into action to improve collaboration in resource sharing among the participants. These strategies include: − release of best practices and worst practices; − activities to promote the knowledge about the network; − cooperation with the Italian national catalogs and consortia; − data analysis about ILL and its performance, related to: turn around time, reciprocity factor, requested/supplied documents imbalance analysis, analysis of ILL requested serial titles and their relationship with consortial e-only acquisitions. The availability of such a high volume of ILL data has allowed for the first time to analyze the trends and gaps of ILL and to help future cooperative acquisitions planning

The Rethinking Resource Sharing Initiative: the NILDE case study in the frame of Italian experiences

NILDE (Network for Inter-Library Document Exchange) is born at the CNR Bologna Research Area Library to provide an effective answer to the needs of libraries in order to guarantee information accessibility, sharing resources through Inter Library Loan (ILL) of returnable and non-returnable items (books and journal articles)

ECMO for COVID-19 patients in Europe and Israel

Since March 15th, 2020, 177 centres from Europe and Israel have joined the study, routinely reporting on the ECMO support they provide to COVID-19 patients. The mean annual number of cases treated with ECMO in the participating centres before the pandemic (2019) was 55. The number of COVID-19 patients has increased rapidly each week reaching 1531 treated patients as of September 14th. The greatest number of cases has been reported from France (n = 385), UK (n = 193), Germany (n = 176), Spain (n = 166), and Italy (n = 136) .The mean age of treated patients was 52.6 years (range 16–80), 79% were male. The ECMO configuration used was VV in 91% of cases, VA in 5% and other in 4%. The mean PaO2 before ECMO implantation was 65 mmHg. The mean duration of ECMO support thus far has been 18 days and the mean ICU length of stay of these patients was 33 days. As of the 14th September, overall 841 patients have been weaned from ECMO support, 601 died during ECMO support, 71 died after withdrawal of ECMO, 79 are still receiving ECMO support and for 10 patients status n.a. . Our preliminary data suggest that patients placed on ECMO with severe refractory respiratory or cardiac failure secondary to COVID-19 have a reasonable (55%) chance of survival. Further extensive data analysis is expected to provide invaluable information on the demographics, severity of illness, indications and different ECMO management strategies in these patients

Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry

Objective: The soluble guanylate cyclase stimulator riociguat is approved for the treatment of adult patients with pulmonary arterial hypertension (PAH) and inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH) following Phase

Nilde in Bess: cosa è cambiato e prospettive future

The paper presents Bess, its creation and development in these years with the introduction of the new service NILDE. The first part explains the structure and the development of Bess; the second part the evolution and growth of NILDE in the consortium

Roman cemeteries in Gazzo Veronese (VR) along the via Claudia Augusta

Il contributo presenta i risultati di una ricerca archeologica condotta dall'Universit\ue0 di verona nel territorio di Gazzo Veronese, ubicato nella bassa pianura di verona. In particolare in questo lavoro, che segue un primo gi\ue0 edito sulla stessa rivista (FOLDER 2016, 370), si presentano i dati raccolti su due necropoli datate fra la fine del I sec. a.C. e la met\ue0 del II d.C. messe in luce lungo la via publica che attraversava il territorio in et\ue0 romana e che \ue8 stata riconosciuta nella Claudia Augusta