Does Italy need family income taxation?

The possible implications of using the family as opposed to the individual as the unit of taxation are not clear. This applies both to work incentives and distributional outcomes. In this paper we evaluate the effects of a hypothetical reform for Italian income taxation with respect to labour supply. In particular, we analyze potential labour supply effects by considering a shift from the current system of individual taxation to a system of family taxation similar to the French family splitting approach. The analysis is based on an econometric model of labour supply that is embedded in a tax–benefit model. Using data from the Bank of Italy Survey of Household Income and Wealth, our simulation results show relatively small effects on the total labour supply but a decrease in female labour supply.tax benefit system, fiscal reform, labour supply, microsimulation

Topological two-body bound states in the interacting Haldane model

We study the topological properties of the two-body bound states in an interacting Haldane model as a function of interparticle interactions. In particular, we identify topological phases where the two-body edge states have either the same or the opposite chirality as compared to single-particle edge states. We highlight that in the moderately interacting regime, which is relevant for the experimental realization with ultracold atoms, the topological transition is affected by the internal structure of the bound state, and the phase boundaries are consequently deformed

Decoding social intentions in human prehensile actions: Insights from a combined kinematics-fMRI study

Consistent evidence suggests that the way we reach and grasp an object is modulated not only by object properties (e.g., size, shape, texture, fragility and weight), but also by the types of intention driving the action, among which the intention to interact with another agent (i.e., social intention). Action observation studies ascribe the neural substrate of this `intentional' component to the putative mirror neuron (pMNS) and the mentalizing (MS) systems. How social intentions are translated into executed actions, however, has yet to be addressed. We conducted a kinematic and a functional Magnetic Resonance Imaging (fMRI) study considering a reach-to-grasp movement performed towards the same object positioned at the same location but with different intentions: passing it to another person (social condition) or putting it on a concave base (individual condition). Kinematics showed that individual and social intentions are characterized by different profiles, with a slower movement at the level of both the reaching (i.e., arm movement) and the grasping (i.e., hand aperture) components. fMRI results showed that: (i) distinct voxel pattern activity for the social and the individual condition are present within the pMNS and the MS during action execution; (ii) decoding accuracies of regions belonging to the pMNS and the MS are correlated, suggesting that these two systems could interact for the generation of appropriate motor commands. Results are discussed in terms of motor simulation and inferential processes as part of a hierarchical generative model for action intention understanding and generation of appropriate motor commands

Hydrogen peroxide-mediated killing of Caenorhabditis elegans by Enterococcus italicus and Lactococcus garvieae isolated from food

In this study, we used the nematode Caenorhabditis elegans as a model to assess the pathogenic potential of two species isolated from food, Enterococcus italicus and Lactococcus garvieae, for which few indications on pathogenicity are available. We identified the conditions under which E. italicus and L. garvieae are able to kill the nematode and suggest that the production of hydrogen peroxide (H2O2) by these two bacteria was involved in the death of C. elegans in our model system. The efficacy of E. italicus and L. garvieae to kill C. elegans differed, most likely related to each species' distinct ability to accumulate H2O2 (4.9 mM and 0.9–1.1 mM, respectively). Genome analysis of both species revealed that the genome of E. italicus contains a gene encoding a NADH oxidase which shows high amino acidic similarity with H2O2 -forming NOX-1 enzymes, while that of L. garvieae contains a gene codifying for a water-forming NADH-oxidase (NOX-2). Reverse transcriptase-PCR experiments carried out in presence of flavin adenine dinucleotide (50 mM) confirmed the presence of the two different genes and likely explains the different toxicity of E. italicus and L. garvieae against C. elegans in our study. The results obtained show for the first time the production of H2O2 in E. italicus and L. garvieae and indicate its toxic effect in the nematode C. elegans

Gender-Specific Aspects in the Clinical Presentation of Cardiovascular Disease

More than a quarter of a million women die each year in the industrialized countries from cardiovascular diseases (CVD), and current projections indicate that this number will continue to rise with our ageing population. Important sex-related differences

Cholinergic Pesticides

Neurotoxicity exerted by organophosphates and carbamate

Ecosystem services sustainability in the Mediterranean Sea: assessment of status and trends using multiple modelling approaches

14 pages, 5 figures, 3 tables, supplementary information https://dx.doi.org/10.1038/srep34162Mediterranean ecosystems support important processes and functions that bring direct benefits to human society. Yet, marine ecosystem services are usually overlooked due to the challenges in identifying and quantifying them. This paper proposes the application of several biophysical and ecosystem modelling approaches to assess spatially and temporally the sustainable use and supply of selected marine ecosystem services. Such services include food provision, water purification, coastal protection, lifecycle maintenance and recreation, focusing on the Mediterranean region. Overall, our study found a higher number of decreasing than increasing trends in the natural capacity of the ecosystems to provide marine and coastal services, while in contrast the opposite was observed to be true for the realised flow of services to humans. Such a study paves the way towards an effective support for Blue Growth and the European maritime policies, although little attention is paid to the quantification of marine ecosystem services in this context. We identify a key challenge of integrating biophysical and socio-economic models as a necessary step to further this researchPeer Reviewe