360 research outputs found

    A Letter to Most Darling Steph

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    Common Factors Related to Illicit Substance Use Among Nurses in North America

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    The prevalence of illicit substance use among registered nurses, though not widely studied or addressed, is understood to be an essential issue facing healthcare professionals. An impaired nurse is defined as someone who has impaired functioning as a result of substance abuse and it interferes with their professional judgment and ability to deliver safe, high quality care. Registered nurses have access to many high-controlled prescription medications, with little oversight, and the opportunity for substance abuse is significant. In our research, we studied the risk factors, the prevalence, and the preventative measures involved in addressing illicit substance use among nurses.https://scholar.dominican.edu/ug-student-posters/1069/thumbnail.jp

    B16: Chikungunya Virus Time Course Infection of Human Macrophages

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    Chikungunya virus (CHIKV) is an Alphavirus spread by Aedes spp. mosquitoes and is responsible for infecting 1.1 million people per year worldwide, including a large epidemic in the western hemisphere in 2014-2015. During the body’s immune response to CHIKV, human macrophages become infected after phagocytosis of CHIKV and undergo induced apoptosis, catalyzing the virus spread in the body. It is presently unclear what macrophage genes, functions, and intracellular signaling pathways are impacted during the early, intermediate, and late stages of CHIKV infection. Therefore we quantified the transcriptional response of human macrophage cells infected with CHIKV at two different timepoints

    Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system.

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    UCHL1 (ubiquitin carboxyterminal hydrolase 1) is a deubiquitinating enzyme that is particularly abundant in neurons. From studies of a spontaneous mutation arising in a mouse line it is clear that loss of function of UCHL1 generates profound degenerative changes in the central nervous system, and it is likely that a proteolytic deficit contributes to the pathology. Here these effects were found to be recapitulated in mice in which the Uchl1 gene had been inactivated by homologous recombination. In addition to the previously documented neuropathology associated with loss of UCHL1 function, axonal swellings were detected in the striatum. In agreement with previously reported findings the loss of UCHL1 function was accompanied by perturbations in ubiquitin pools, but glutathione levels were also significantly depleted in the brains of the knockout mice, suggesting that oxidative defense mechanisms may be doubly compromised. To determine if, in addition to its role in the central nervous system, UCHL1 function is also required for homeostasis of the enteric nervous system the gastrointestinal tract was analyzed in UCHL1 knockout mice. The mice displayed functional changes and morphological changes in gut neurons that preceded degenerative changes in the brain. The changes were qualitatively and quantitatively similar to those observed in wild type mice of much greater age, and strongly resemble changes reported for elderly humans. UCHL1 knockout mice should therefore serve as a useful model of gut aging

    Education Faculty as Knowledge Brokers: Competing for Access to New York State Print Media and Policy Influence

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    In an environment in which new policy entrepreneurs and networks are influencing policy and public opinion, many university faculty are increasingly seeking ways to mobilize knowledge beyond academic conferences and journals. Using New York state as a case, we searched Access World News to compare the level of media access of academics with other knowledge brokering organizations (KBOs; e.g. think tanks, teachers’ unions, advocacy organizations, etc.). Our data shows relatively low levels of access for academics and provides profiles of those academics with high levels of access and what we might learn from them. We provide a discussion of the strategies of those academics who are successful at accessing the media and how disinvestment by the state. from higher education and current incentive systems make it more difficult for academics to engage in knowledge mobilization beyond universities

    INTRODUCING AUTHENTIC RESEARCH EXPERIENCE AT THE UNDERGRADUATE LEVEL

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    One of the challenges facing new graduates is that they don’t necessarily know what lies out there for them once they have finished their degrees. Not all students are aware of the jobs they are qualified for, or the post-graduate opportunities that may be available to them. In an attempt to engage with undergraduate students and give them a glimpse into life after graduation, we ran a pilot Cancer Research Summer Project (CRSP). In this pilot program we took four high-achieving second-year biomedical science students through a three-week research project, which exposed them to a real-life laboratory experience, and also provided them with additional skills training in areas such as scientific journal article writing and database mining. Students were given a fully immersive laboratory experience, receiving the type of instruction and supervision they could expect in either post-graduate study or out in the workforce, with some autonomy, and successes and failures driven by their own hands. Students reported that the CRSP provided a fantastic opportunity and made them aware of a new world of possibilities after graduation. At the end of the project the students were provided with a supporting letter to include in their curriculum vitae, showing evidence of the industry-relevant training they undertook. Work experience is often required of new employees, especially in the field of biomedical research. This project had the additional benefit of providing students with vitally important first-hand experience. It also provided a vehicle to demonstrate to the students that the skills and theories they learn in their undergraduate courses can be directly transferred to the workplace or in their further studies. With the continuation of this project into the future, the hope is that students can gain a broader understanding of the opportunities available to them and that more students will be encouraged to take up post-graduate study

    The Student Movement Volume 108 Issue 9: Perfect Landing: Acrofest Comes to Andrews University

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    HUMANS Blessings Outnumbering The Autumn Leaves, Savannah Tyler The James White Library Archives, Grace No ARTS & ENTERTAINMENT A Charlie Brown Thanksgiving!, Lexie Dunham Art: Reclaiming the Narrative, Madison Vath A Trip to Detroit Through Nandi Comer\u27s Eyes, Ameilia Stefanescu NEWS Taking Flight at Acrofest, Nate Miller Andrews Celebrates Veterans, Andrew Francis Instruments of His Peace in a Broken World, Anna Rybachek IDEAS Are Aliens Real?, Katie Davis Stay Vaccinated for the Sassy Man Epidemic, Charisse Lapuebla The Thanksgiving Debate, Ruben Colón PULSE Artificial Intelligence: Are We Playing God?, Alyssa Caruthers How Mission Work Impacts the Missionary: Advice for SMs, Caitlin Adap Moral Conflict Part 2, Katie Davis, The Illusion of Romantic Love, Nicole Compton-Gray LAST WORD The Joys of Journaling, Ian Freemanhttps://digitalcommons.andrews.edu/sm-108/1008/thumbnail.jp
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