Soft gluon radiation and energy dependence of total hadronic cross-sections

An impact parameter representation for soft gluon radiation is applied to obtain both the initial decrease of the total cross-section ($\sigma_{tot}$) for proton-proton collisions as well as the later rise of $\sigma_{tot}$ with energy for both $pp$ and $p\bar{p}$. The non-perturbative soft part of the eikonal includes only limited low energy gluon emission and leads to the initial decrease in the proton-proton cross- section. On the other hand, the rapid rise in the hard, perturbative jet part of the eikonal is tamed into the experimentally observed mild increase by soft gluon radiation whose maximum energy rises slowly with energy.Comment: 30 pages, 6 figures. Version accepted for publication in Physical Review D. Additional section with explanatory material added making the paper more self contained and two figures changed to have a complete summary of the available accelerator dat

Subluxación vertebral como complicación a una descompresión ventral-cervical slot

Este trabajo describe un caso clínico de hernia discal cervical Hansen tipo I en un perro de raza Alaska malamute de 4 años de edad que fue resuelta mediante descompresión ventral, creando un slot con el fin de retirar el material extruido. La evolución fue buena pero, a las 5 semanas de la cirugía, se produjo una subluxación y colapso vertebral en el lugar donde se había practicado la descompresión. Se trató la inestabilidad mediante tornillos. de 4 mm de diámetro anclados en los cuerpos vertebrales adyacentes y cemento de metil-metacrilato.A case of Hansen Type I cervical disk herniation in a 4-year-old Alaska malamute is described. Surgical treatment consisted of a ventral decompression through a slot in order to retrieve the extruded material. The follow-up period was uneventful until subluxation and vertebral collapse ocurred at the surgical site 5 weeks postoperatively. The subluxation was stabilized with 4 mm. screws and methylmetacrilate bone cement

Hepatozoonosis canina.Estudio retrospectivo de 8 casos clínicos

Se describen ocho casos de hepatozonoosis canina diagnosticados en la Clínica Veterinaria Canis mediante identificación del microorganismo en extensiones de sangre y lo médula ósea. Se incluyen el cuadro clínico, pruebas laboratoriales de diagnóstico, pautas de tratamiento y evolución clínica.Hight cases of canine hepatozoonosis diagnosed at Clinica Veterinaria Canis by identzfication of the organism on blood and/or bone marrow smears are descried. Clinical signs, hematologic and biochemistry findings, diferent treatment, protocols and jollow up are included

Getting the message straight: effects of a brief hepatitis prevention intervention among injection drug users

To redress gaps in injection drug users' (IDUs) knowledge about hepatitis risk and prevention, we developed a brief intervention to be delivered to IDUs at syringe exchange programs (SEPs) in three US cities. Following a month-long campaign in which intervention packets containing novel injection hygiene supplies and written materials were distributed to every client at each visit, intervention effectiveness was evaluated by comparing exposed and unexposed participants' self-reported injection practices. Over one-quarter of the exposed group began using the novel hygiene supplies which included an absorbent pad ("Safety Square") to stanch blood flow post-injection. Compared to those unexposed to the intervention, a smaller but still substantial number of exposed participants continued to inappropriately use alcohol pads post-injection despite exposure to written messages to the contrary (22.8% vs. 30.0%). It should also be noted that for those exposed to the intervention, 8% may have misused Safety Squares as part of pre-injection preparation of their injection site; attention should be paid to providing explicit and accurate instruction on the use of any health promotion materials being distributed. While this study indicates that passive introduction of risk reduction materials in injection drug users through syringe exchange programs can be an economical and relatively simple method of changing behaviors, discussions with SEP clients regarding explicit instructions about injection hygiene and appropriate use of novel risk reduction materials is also needed in order to optimize the potential for adoption of health promotion behaviors. The study results suggest that SEP staff should provide their clients with brief, frequent verbal reminders about the appropriate use when distributing risk reduction materials. Issues related to format and language of written materials are discussed

Redox signals at the ER-mitochondria interface control melanoma progression.

Reactive oxygen species (ROS) are emerging as important regulators of cancer growth and metastatic spread. However, how cells integrate redox signals to affect cancer progression is not fully understood. Mitochondria are cellular redox hubs, which are highly regulated by interactions with neighboring organelles. Here, we investigated how ROS at the endoplasmic reticulum (ER)-mitochondria interface are generated and translated to affect melanoma outcome. We show that TMX1 and TMX3 oxidoreductases, which promote ER-mitochondria communication, are upregulated in melanoma cells and patient samples. TMX knockdown altered mitochondrial organization, enhanced bioenergetics, and elevated mitochondrial- and NOX4-derived ROS. The TMX-knockdown-induced oxidative stress suppressed melanoma proliferation, migration, and xenograft tumor growth by inhibiting NFAT1. Furthermore, we identified NFAT1-positive and NFAT1-negative melanoma subgroups, wherein NFAT1 expression correlates with melanoma stage and metastatic potential. Integrative bioinformatics revealed that genes coding for mitochondrial- and redox-related proteins are under NFAT1 control and indicated that TMX1, TMX3, and NFAT1 are associated with poor disease outcome. Our study unravels a novel redox-controlled ER-mitochondria-NFAT1 signaling loop that regulates melanoma pathobiology and provides biomarkers indicative of aggressive disease

Landmark detection in 2D bioimages for geometric morphometrics: a multi-resolution tree-based approach

The detection of anatomical landmarks in bioimages is a necessary but tedious step for geometric morphometrics studies in many research domains. We propose variants of a multi-resolution tree-based approach to speed-up the detection of landmarks in bioimages. We extensively evaluate our method variants on three different datasets (cephalometric, zebrafish, and drosophila images). We identify the key method parameters (notably the multi-resolution) and report results with respect to human ground truths and existing methods. Our method achieves recognition performances competitive with current existing approaches while being generic and fast. The algorithms are integrated in the open-source Cytomine software and we provide parameter configuration guidelines so that they can be easily exploited by end-users. Finally, datasets are readily available through a Cytomine server to foster future research

Jet Reconstruction in Heavy Ion Collisions

We examine the problem of jet reconstruction at heavy-ion colliders using jet-area-based background subtraction tools as provided by FastJet. We use Monte Carlo simulations with and without quenching to study the performance of several jet algorithms, including the option of filtering, under conditions corresponding to RHIC and LHC collisions. We find that most standard algorithms perform well, though the anti-kt and filtered Cambridge/Aachen algorithms have clear advantages in terms of the reconstructed transverse-momentum offset and dispersion.Comment: 31 pages, 17 figure