Serial Position Effects in Short-term Visual Memory: A SIMPLE Explanation?

A version of Sternberg’s (1966) short-term, visual memory recognition paradigm with pictures of unfamiliar faces as stimuli was used in three experiments to assess the applicability of the distinctiveness based SIMPLE model proposed by Brown, Neath & Chater (2002). Initial simulations indicated that the amount of recency predicted increased as the parameter measuring the psychological distinctiveness of the stimulus material (c) increased, and that the amount of primacy was dependent on the extent of proactive interference from previously presented stimuli. The data from experiment 1, which used memory lists of four and five faces varying in visual similarity confirmed the predicted, extended recency effect. However, changes in visual similarity were not found to produce changes in c. In Experiments 2 and 3, the conditions that influence the magnitude of c were explored. These revealed that both the familiarity of the stimulus class before testing, and changes in familiarity due to perceptual learning, influenced distinctiveness as indexed by the parameter c. Overall the empirical data from all three experiments were well-fit by SIMPLE

A SWOT Analysis of the IS Academic Discipline in Australia

Abstract: The study provides a review of changing perceptions of the Information Systems (IS) academic discipline in Australia across the ten year span from 2005 until 2015. The main source of data for this analysis is a series of annual surveys of Heads of Information Systems Departments across all Australian universities. The surveys incorporated questions regarding the perceived Strengths, Weaknesses, Opportunities and Threats pertaining at the time to the IS academic discipline in Australia. A review of the annual judgements, augmented by data from other sources, while revealing the inevitable changes of focus over time, brings to the fore a range of persistent and enduring issues demanding the attention of Australia’s IS academics. Collaborative Doctoral Consortia are proposed as effective mechanisms to exploit the strengths and opportunities and to redress weaknesses and threats identified

A SWOT Analysis of the IS Academic Discipline in Australia

The study deals with changing perceptions of the Information Systems (IS) academic discipline in Australia across the ten year span from 2005 until 2014. The main source of data for this analysis is a series of annual surveys of Heads of Information Systems Departments across all Australian universities. The surveys incorporated questions regarding the perceived Strengths, Weaknesses, Opportunities and Threats pertaining at the time to the IS academic discipline in Australia. An analysis of the annual judgements, augmented by data from other sources, while revealing the inevitable changes of focus over time, brings to the fore a range of persistent and enduring issues demanding the attention of Australia’s IS academics. Collaborative Doctoral Consortia are proposed as effective mechanisms to exploit the strengths and opportunities and to redress weaknesses and threats identified

Breast cancer risk and imprinting methylation in blood

Date of Acceptance: 17/08/2015 Acknowledgements This study was supported by the Breast Cancer Campaign (2008MayPR46) and Fraserburgh Moonlight Prowl Breast Cancer Charity. PH, GH and GWH acknowledge the support of the Scottish Government. We would like to thank Val Bain and Michela Donnarumma for help with the data and sample collection.Peer reviewedPublisher PD

Training for a transformed service : the experience of learners in 2016

This article explores the training and early practice experience of the first cohort of probation learners trained under the auspices of ‘Transforming Rehabilitation’ (TR). It draws on interviews with learners qualifying in 2016 in order to examine the adequacy of their training and their early perceptions of delivering TR as qualified practitioners. While highlighting their training as stressful and noting issues with TR and some implications of the highly risk-focused nature of NPS work in particular, participants were generally positive about their training and early post-qualification experiences. Some inferences are drawn in relation to the future approach to training

Novel DNA methylation profiles associated with key gene regulation and transcription pathways in blood and placenta of growth-restricted neonates

BB/H012494/1/ Biotechnology and Biological Sciences Research Counci

Assessing the Impact of Light/Shallow Precipitation Retrievals from Satellite-Based Observations Using Surface Radar and Micro Rain Radar Observations

The accurate representation of precipitation across the Earth’s surface is crucial to furthering our knowledge and understanding of the Earth System and its component processes. Precipitation poses a number of challenges, particularly due to the variability of precipitation over time and space and whether it falls as snow or rain. While conventional measures of precipitation are reasonably good at the location of their measurement, their distribution across the Earth’s surface is uneven with some regions having no surface measurements. Spaceborne sensors have the capability of providing regular observations across the Earth’s surface that can provide estimates of precipitation. However,the estimation of precipitation from satellite observations is not necessarily straightforward. Visible and/or infrared techniques rely upon imprecise cloud-top to surface precipitation relationships, while the sensitivity of passive microwave techniques to different precipitation types is not consistent. Active microwave (radar) observations provide the most direct satellite measurements of precipitation but cannot provide estimates close to the surface and are generally not sufficiently sensitive to resolve light precipitation. This is particularly problematic at mid to high latitudes, where light and/or shallow precipitation dominates. This paper compares measurements made by ground-based weather radars, Micro Rain Radars and the spaceborne Dual-frequency Precipitation Radar to study both light precipitation intensity and shallow precipitation occurrence and to assess their impact on satellites retrievals of precipitation at the mid to high latitudes

Airport route development: a survey of current practice

To develop air services and in many cases tourism flows, airports focus their marketing effort on airlines through a process known as route development. Whilst route development is a well-known concept within the airport industry it has received limited attention in academic or industry literature. As a result little knowledge is shared about why airports use route development, what are the most common methods and what is the general level of involvement. To fill the gap, this paper investigates airport route development practice using an online survey of 124 airports worldwide. Findings show that the vast majority of airports are actively involved in route development for a range of objectives and that the process and level of involvement is extensive, although this often depends on airport size, location or ownership. Results are particularly relevant to airports that are less advanced in route development activities and also those seeking to debate route and tourism development strategies with stakeholders

Binomial coefficients, Catalan numbers and Lucas quotients

Let $p$ be an odd prime and let $a,m$ be integers with $a>0$ and $m \not\equiv0\pmod p$. In this paper we determine $\sum_{k=0}^{p^a-1}\binom{2k}{k+d}/m^k$ mod $p^2$ for $d=0,1$; for example, $$\sum_{k=0}^{p^a-1}\frac{\binom{2k}k}{m^k}\equiv\left(\frac{m^2-4m}{p^a}\right)+\left(\frac{m^2-4m}{p^{a-1}}\right)u_{p-(\frac{m^2-4m}{p})}\pmod{p^2},$$ where $(-)$ is the Jacobi symbol, and $\{u_n\}_{n\geqslant0}$ is the Lucas sequence given by $u_0=0$, $u_1=1$ and $u_{n+1}=(m-2)u_n-u_{n-1}$ for $n=1,2,3,\ldots$. As an application, we determine $\sum_{0<k<p^a,\, k\equiv r\pmod{p-1}}C_k$ modulo $p^2$ for any integer $r$, where $C_k$ denotes the Catalan number $\binom{2k}k/(k+1)$. We also pose some related conjectures.Comment: 24 pages. Correct few typo

A non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation

Nucleotide-metabolizing ectoenzymes are endowed with an extracellular catalytic domain, which is involved in regulating the extracellular nucleotide/nucleoside balance. The tumor microenvironment contains high levels of adenosine (ADO) generated by this enzymatic network, thus promoting tumor growth by inhibiting anti-tumor immune responses. ADO inhibition in melanoma murine models limits tumor metastases and restores anti-tumor immune responses. This work investigates the expression and function of ectoenzymes in primary human melanoma cell lines. All of latter cells expressed CD38, CD39, CD73, and CD203a/PC-1, and produced ADO from AMP and NAD+. Melanoma cells inhibited T cell proliferation through an ADO-dependent mechanism, since such inhibition was reverted using CD38/CD73 specific inhibitors. Melanoma cells abolished the function of effector memory, central memory and reduced na\uc3\uafve CD4+ T cell proliferation. Accordingly, phosphorylation of S6 ribosomal protein, p38 and Stat1 was lower in activated memory cells than in na\uc3\uafve CD4+ T lymphocytes. Melanoma cells also inhibited proliferation of na\uc3\uafve, memory and -to a lesser extent- of effector CD8+ T cells. These different inhibitory effects correlated with distinct patterns of expression of the ADO receptor A2a and A2b. These results show that primary human melanoma cell lines suppress in vitro T cell proliferation through an adenosinergic pathway in which CD38 and CD73 play a prominent role