247 research outputs found

    Online-Lernen mit Studierenden : Beispiel am Projekt „Wasser“

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    Im WS 1999/2000 wird an der Universität Gießen zum ersten Mal im deutschsprachigen Raum ein Seminar für Lehramtsstudierende der Biologie (Thema Wasser) angeboten, das ausschließlich Online im Internet stattfindet. Sowohl zur Wissensaneignung als auch zur Kommunikation zwischen den Teilnehmern wird eine speziell entwickelte Software eingesetzt. Der nachfolgende Beitrag legt einige grundsätzliche Überlegungen zum Online-Lernen dar, die dem Programm zu Grunde liegen. Am Ende der Ausführungen wird kurz der Online- Kurs „Wasser“ vorgestellt

    Integration of a water scrubbing technique and two-stage pressurized anaerobic digestion in one process

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    Two-stage pressurized anaerobic digestion is a promising technology. This technology integrates in one process biogas production with upgrading and pressure boosting for grid injection. To investigate whether the efficiency of this novel system could be further increased, a water scrubbing system was integrated into the methanogensis step. Therefore, six leach-bed reactors were used for hydrolysis/acidification and a 30-L pressurized anaerobic filter operated at 9 bar was adopted for acetogenesis/methanogenesis. The fermentation liquid of the pressurized anaerobic filter was circulated periodically via a flash tank, operating at atmospheric pressure. Due to the pressure drop, part of dissolved carbon dioxide was released from the liquid phase into the flash tank. The depressurized fermentation liquid was then recycled to the pressurized reactor. Three different flow rates (0 L·day1^{-1}, 20 L·day1^{-1} and 40 L·day1^{-1}) were tested with three repetitions. As the daily recycled flashed liquid flow was increased from 0 to 40 L, six times as much as the daily feeding, the methane content in the biogas increased from 75 molar percent (mol%) to 87 mol%. The pH value of the substrate in the methane reactor rose simultaneously from 6.5 to 6.7. The experimental data were verified by calculation

    Serological Response to Treatment of Syphilis According to Disease Stage and HIV Status

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    The serological response to treatment was studied in 264 syphilis patients; it was influenced by syphilis stage but not by human immunodeficiency virus infection and reinfection. Some of the recommendations of current guidelines are critically discussed, and amendments are propose

    Determination of Binding Sites on Trastuzumab and Pertuzumab to Selective Affimers Using Hydrogen-Deuterium Exchange Mass Spectrometry

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    Hydrogen-deuterium exchange mass spectrometry (HDX-MS) is a method to probe the solvent accessibility and conformational dynamics of a protein or a protein-ligand complex with respect to exchangeable amide hydrogens. Here, we present the application of HDX-MS to determine the binding sites of Affimer reagents to the monoclonal antibodies trastuzumab and pertuzumab, respectively. Intact and subunit level HDX-MS analysis of antibody-affimer complexes showed significant protection from HDX in the antibody Fab region upon affimer binding. Bottom-up HDX-MS experiments including online pepsin digestion revealed that the binding sites of the affimer reagents were mainly located in the complementarity-determining region (CDR) 2 of the heavy chain of the respective antibodies. Three-dimensional models of the binding interaction between the affimer reagents and the antibodies were built by homology modeling and molecular docking based on the HDX data.</p

    Infrared Conductivity in Layered dd-wave Superconductors

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    We calculate the infrared conductivity of a stack of coupled, two-dimensional superconducting planes within the Fermi liquid theory of superconductivity. We include the effects of random scattering processes and show that the presence of even a small concentration of resonant impurities, in a dd-wave superconductor, has an important effect on both the in-plane and cc-axis transport properties, which could serve as signatures for dd-wave pairing.Comment: 18 pages in a RevTex (3.0) file plus 5 postscript figures (uuencoded). Replaced with minor changes as it will appear in the Physical Review B {\bf 52} issue 1 Oct. 199

    Unconventional Pairing in Heavy Fermion Metals

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    The Fermi-liquid theory of superconductivity is applicable to a broad range of systems that are candidates for unconventional pairing. Fundamental differences between unconventional and conventional anisotropic superconductors are illustrated by the unique effects that impurities have on the low-temperature transport properties of unconventional superconductors. For special classes of unconventional superconductors the low-temperature transport coefficients are {\it universal}, i.e. independent of the impurity concentration and scattering phase shift. The existence of a universal limit depends on the symmetry of the order parameter and is achieved at low temperatures kBTγΔ0k_B T \ll \gamma \ll \Delta_0, where γ\gamma is the bandwidth of the impurity induced Andreev bound states. In the case of UPt3_3 thermal conductivity measurements favor an E1gE_{1g} or E2uE_{2u} ground state. Measurements at ultra-low temperatures should distinguish different pairing states.Comment: 8 pages in a LaTex (3.0) file plus 5 Figures in PostScript. To appear in the Proceedings of the XXI International Conference on Low Temperature Physics held in Prague, 8-14 August 199

    Экология и безопасность в техносфере: современные проблемы и пути решения: сборник трудов Всероссийской научно-практической конференции молодых ученых, аспирантов и студентов, г. Юрга, 23-25 ноября 2017 г.

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    В сборнике представлены материалы по современным проблемам экологической и техногенной безопасности, технологий переработки отходов, информационно- компьютерных технологий в решении задач экологии и БЖД, а также современных технологий ликвидаций ЧС и технического обеспечения аварийно-спасательных работ; содержатся результаты теоретических исследований и практической реализации научно-исследовательских работ. Материалы сборника представляют интерес для преподавателей, научных сотрудников, аспирантов и студентов по направлению «техносферная безопасность»
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