41 research outputs found
Temperature dependence of spin diffusion length and spin Hall angle in Au and Pt
We have studied the spin transport and the spin Hall effect as a function of
temperature for platinum (Pt) and gold (Au) in lateral spin valve structures.
First, by using the spin absorption technique, we extract the spin diffusion
length of Pt and Au. Secondly, using the same devices, we have measured the
spin Hall conductivity and analyzed its evolution with temperature to identify
the dominant scattering mechanisms behind the spin Hall effect. This analysis
confirms that the intrinsic mechanism dominates in Pt whereas extrinsic effects
are more relevant in Au. Moreover, we identify and quantify the phonon-induced
skew scattering. We show that this contribution to skew scattering becomes
relevant in metals such as Au, with a low residual resistivity.Comment: 13 pages, 5 figure
Seebeck Effect in Nanoscale Ferromagnets
We present a theory of the Seebeck effect in nanoscale ferromagnets with
dimensions smaller than the spin diffusion length. The spin accumulation
generated by a temperature gradient strongly affects the thermopower. We also
identify a correction arising from the transverse temperature gradient induced
by the anomalous Ettingshausen effect. The effect of an induced spin-heat accu-
mulation gradient is considered as well. The importance of these effects for
nanoscale ferromagnets is illustrated by ab initio calculations for dilute
ferromagnetic alloys.Comment: 5 pages, 2 figure
Interfacial mechanism in the anomalous Hall effect of Co/BiO bilayers
Oxide interfaces are a source of spin-orbit coupling which can lead to novel
spin-to-charge conversion effects. In this work the contribution of the
BiO interface to the anomalous Hall effect of Co is experimentally
studied in Co/BiO bilayers. We evidence a variation of 40% in the AHE
of Co when a BiO capping layer is added to the ferromagnet. This strong
variation is attributed to an additional source of asymmetric transport in
Co/BiO bilayers that originates from the Co/BiO interface and
contributes to the skew scattering.Comment: 7 pages, 4 figure
Tuning the spin Hall effect of Pt from the moderately dirty to the superclean regime
We systematically measure and analyze the spin diffusion length and the spin Hall effect in Pt with a wide range of conductivities using the spin absorption method in lateral spin valve devices. We observe a linear relation between the spin diffusion length and the conductivity, evidencing that the spin relaxation in Pt is governed by the Elliott-Yafet mechanism. We find a single intrinsic spin Hall conductivity (σintSH=1600±150Ω−1cm−1) for Pt in the full range studied which is in good agreement with theory. We have obtained the crossover between the moderately dirty and the superclean scaling regimes of the spin Hall effect by tuning the conductivity. This is equivalent to that obtained for the anomalous Hall effect. Our results explain the spread of the spin Hall angle values in the literature and find a route to maximize this important parameter
Tuning the spin Hall effect of Pt from the moderately dirty to the superclean regime
We systematically measure and analyze the spin diffusion length and the spin
Hall effect in Pt with a wide range of conductivities using the spin absorption
method in lateral spin valve devices. We observe a linear relation between the
spin diffusion length and the conductivity, evidencing that the spin relaxation
in Pt is governed by the Elliott-Yafet mechanism. We find a single intrinsic
spin Hall conductivity ()
for Pt in the full range studied which is in good agreement with theory. For
the first time we have obtained the crossover between the moderately dirty and
the superclean scaling regimes of the spin Hall effect by tuning the
conductivity. This is equivalent to that obtained for the anomalous Hall
effect. Our results explain the spread of the spin Hall angle values in the
literature and find a route to maximize this important parameter.Comment: 11 pages, 4 figure
Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene
A large body of evidence strongly suggests that the p53 tumor suppressor pathway is central in reducing cancer frequency in vertebrates. The protein product of the haploinsufficient mouse double minute 2 (MDM2) oncogene binds to and inhibits the p53 protein. Recent studies of human genetic variants in p53 and MDM2 have shown that single nucleotide polymorphisms (SNPs) can affect p53 signaling, confer cancer risk, and suggest that the pathway is under evolutionary selective pressure (1–4). In this report, we analyze the haplotype structure of MDM4, a structural homolog of MDM2, in several different human populations. Unusual patterns of linkage disequilibrium (LD) in the haplotype distribution of MDM4 indicate the presence of candidate SNPs that may also modify the efficacy of the p53 pathway. Association studies in 5 different patient populations reveal that these SNPs in MDM4 confer an increased risk for, or early onset of, human breast and ovarian cancers in Ashkenazi Jewish and European cohorts, respectively. This report not only implicates MDM4 as a key regulator of tumorigenesis in the human breast and ovary, but also exploits for the first time evolutionary driven linkage disequilibrium as a means to select SNPs of p53 pathway genes that might be clinically relevant
Altered tumor formation and evolutionary selection of genetic variants in the human MDM4 oncogene
A large body of evidence strongly suggests that the p53 tumor suppressor pathway is central in reducing cancer frequency in vertebrates. The protein product of the haploinsufficient mouse double minute 2 (MDM2) oncogene binds to and inhibits the p53 protein. Recent studies of human genetic variants in p53 and MDM2 have shown that single nucleotide polymorphisms (SNPs) can affect p53 signaling, confer cancer risk, and suggest that the pathway is under evolutionary selective pressure (1–4). In this report, we analyze the haplotype structure of MDM4, a structural homolog of MDM2, in several different human populations. Unusual patterns of linkage disequilibrium (LD) in the haplotype distribution of MDM4 indicate the presence of candidate SNPs that may also modify the efficacy of the p53 pathway. Association studies in 5 different patient populations reveal that these SNPs in MDM4 confer an increased risk for, or early onset of, human breast and ovarian cancers in Ashkenazi Jewish and European cohorts, respectively. This report not only implicates MDM4 as a key regulator of tumorigenesis in the human breast and ovary, but also exploits for the first time evolutionary driven linkage disequilibrium as a means to select SNPs of p53 pathway genes that might be clinically relevant
Post-mortem histology in transient receptor potential cation channel subfamily V member 6 (TRPV6) under-mineralising skeletal dysplasia suggests postnatal skeletal recovery:a case report
Unveiling the mechanisms of the spin Hall effect in Ta
Spin-to-charge current interconversions are widely exploited for the
generation and detection of pure spin currents and are key ingredients for
future spintronic devices including spin-orbit torques and spin-orbit logic
circuits. In case of the spin Hall effect, different mechanisms contribute to
the phenomenon and determining the leading contribution is peremptory for
achieving the largest conversion efficiencies. Here, we experimentally
demonstrate the dominance of the intrinsic mechanism of the spin Hall effect in
highly-resistive Ta. We obtain an intrinsic spin Hall conductivity for
-Ta of -820120 (/e) from spin
absorption experiments in a large set of lateral spin valve devices. The
predominance of the intrinsic mechanism in Ta allows us to linearly enhance the
spin Hall angle by tuning the resistivity of Ta, reaching up to -353%, the
largest reported value for a pure metal.Comment: 9 pages and 4 figures + Supplemental Material (2 pages, 3 figures
