The effects of a chemosterilant (Mestranol) on population and behavior in the Richardson's ground squirrel (Spermophilus richardsonii) in Alberta

A chemosterilant, mestranol, was administered to three populations of Richardson's ground squirrel in southeastern Alberta. Mestranol was given to all squirrels in one plot, to only 50 percent in another plot, while a third plot remained as control. In all plots social behavior and population dynamics were followed over two seasons by live trapping and visual observations. Mestranol sterilized all females who received the drug shortly before or in early pregnancy; accordingly the birth rates were reduced. Levels of total aggression were also reduced but increased survival and immigration rates nullified the effects of the treatment during the first season. During the second season, low birth rates due to repeated treatment in one plot and to adult emigration and unknown causes in the other, were not compensated for by immigration. As a result of the repeated mestranol treatment and in one case also of adult emigration, the numbers of squirrels were reduced in the vicinity, thus limiting potential immigration in the treated plots. As a consequence, both treated populations crashed, demonstrating the effectiveness of mestranol

Investigation of test methods, material properties, and processes for solar cell encapsulants

The development of pottant compounds is emphasized. Formulation of the butyl acrylate syrup/casting pottant was completed. The formulation contains an ultraviolet stabilizer system and may be cured with an initiator that, unlike former selections, presents no shipping of handling hazards to the user. The catalyzed syrup is stable at room temperature and has a pot life of at least eight hours. The formulation of the ethylene/methyl acrylate lamination pottant was also completed. This compound is the alternative pottant to EVA and is similarly produced as an extruded sheet that is wound into rolls. This resin is inherently nonblocking

Alien Registration- Goulet, Marie A. (Sanford, York County)

https://digitalmaine.com/alien_docs/3585/thumbnail.jp

La dimension religieuse des revendications autochtones au Canada

L’objectif de cet article est d’identifier et d’analyser la dimension religieuse des affirmations identitaires et des revendications territoriales au Canada, tant du côté de la Couronne au nom de laquelle le gouvernement canadien agit, que du côté autochtone qui, depuis toujours, résiste au projet colonial britannique et canadien. Une attention particulière est apportée aux multiples déclarations récentes des Premières Nations qui mettent en valeur leur relation au Créateur comme fondement de leurs droits ancestraux. Les conflits qui opposent sans cesse les autochtones et les allochtones au Canada et au Québec sont enracinés dans des imaginaires religieux collectifs, chrétien et autochtone, qu’il faut interroger afin de comprendre comment ils divisent les communautés autochtones elles-mêmes entre soi-disant traditionalistes et progressistes.The author identifies and analyzes the religious dimension of statements of identity and of land claims in Canada, on the part of the government of Canada acting in the name of the Crown and on the part of First Nations who for centuries have resisted the colonial ambitions of British and Canadian governments. The paper focuses on the numerous déclarations of First Nations that emphasize their relationship to the Creator as the foundation of their ancestral rights. Unless the collective religious imagination of both parties, Christian and Aboriginal, are examined they will continue to inspire conflicts that oppose not only Aboriginal Peoples and governments in Canada and Québec but also drive Christian and Traditionalists against each other within Aboriginal Communities

Alien Registration- Goulet, Albert Joseph A. (Ashland, Aroostook County)

https://digitalmaine.com/alien_docs/27379/thumbnail.jp

Comprehensive structural model of the mechanochemical cycle of a mitotic motor highlights molecular adaptations in the kinesin family

Kinesins are responsible for a wide variety of microtubule-based, ATP-dependent functions. Their motor domain drives these activities but the molecular adaptations that specify these diverse and essential cellular activities are poorly understood. It has been assumed that the first identified kinesin - the transport motor kinesin-1 – is the mechanistic paradigm for the entire superfamily, but accumulating evidence suggests that this is not the case. To address the deficits in our understanding of the molecular basis of functional divergence within the kinesin superfamily, we studied kinesin-5s, which are essential mitotic motors whose inhibition blocks cell division. Using cryo-electron microscopy and subnanometer resolution structure determination, we have visualised conformations of microtubule-bound human kinesin-5 motor domain at successive steps in its ATPase cycle. Following ATP hydrolysis, nucleotide-dependent conformational changes in the active site are allosterically propagated into rotations of the motor domain and uncurling of the drugbinding loop L5. In addition, the mechanical neck-linker element that is crucial for motor stepping undergoes discrete, ordered displacements. We also observed large reorientations of the motor N-terminus that indicate its importance for kinesin-5 function through control of neck-linker conformation. A kinesin-5 mutant lacking this N-terminus is enzymatically active, and ATP-dependent neck-linker movement and motility is defective although not ablated. All these aspects of kinesin-5 mechanochemistry are distinct from kinesin-1. Our findings directly demonstrate the regulatory role of the kinesin-5 N-terminus in collaboration with the motor’s structured neck-linker, and highlight the multiple adaptations within kinesin motor domains that tune their mechanochemistries according to distinct functional requirements