Phase transition for a non-attractive infection process in heterogeneous environment

We consider a non-attractive three state contact process on $\mathbb Z$ and prove that there exists a regime of survival as well as a regime of extinction. In more detail, the process can be regarded as an infection process in a dynamic environment, where non-infected sites are either healthy or passive. Infected sites can recover only if they have a healthy site nearby, whereas non-infected sites may become infected only if there is no healthy and at least one infected site nearby. The transition probabilities are governed by a global parameter $q$: for large $q$, the infection dies out, and for small enough $q$, we observe its survival. The result is obtained by a coupling to a discrete time Markov chain, using its drift properties in the respective regimes

Sterol regulatory element binding protein-1 (SREBP1) gene expression is similarly increased in polycystic ovary syndrome and endometrial cancer

Introduction: Women with polycystic ovary syndrome (PCOS) have a 3-fold higher risk of endometrial cancer (EC). Insulin resistance and hyperlipidaemia may be pertinent factors in the pathogenesis of both conditions. The aim of this study was to investigate endometrial Sterol Regulatory Element Binding Protein-1 gene (SREBP1) expression in PCOS and EC endometrium, and to correlate endometrial SREBP1 expression with serum lipid profiles. Material and methods: A cross-sectional study was performed at Nottingham University Hospital, United Kingdom. A total of 102 women (PCOS, EC and controls; 34 participants in each group) were recruited. Clinical and biochemical assessments were performed before endometrial biopsies were obtained from all participants. Taqman real-time PCR for endometrial SREBP1 and its systemic protein expression were analysed. Results: The BMI of women with PCOS (29.28 (±2.91) kg/m2) and controls (28.58 (±2.62) kg/m2) was not significantly different. Women with EC had a higher mean BMI (32.22 (±5.70) kg/m2). SREBP1 gene expression was significantly increased in PCOS and EC endometrium compared to controls (p<0.0001). SREBP1 gene expression was positively correlated with BMI (r=0.017, p=0.921) and waist-hip ratio (r=0.023, p=0.544) in PCOS, but this was not statistically significant. Similarly, statistically insignificant positive correlations were found between endometrial SREBP1 gene expression and BMI in EC (r=0.643, p=0.06) and waist-hip ratio (r=0.096, p=0.073). SREBP1 expression was significantly positively correlated with triglyceride in both PCOS and EC (p= 0.028 and p=0.027). Quantitative serum SREBP1 correlated with endometrial gene expression (p<0.05). Conclusions: SREBP1 gene expression is significantly increased in the endometrium of PCOS and EC women compared with controls and positively correlates with serum triglyceride in both PCOS and EC

Balbín, Carlos F. Impacto del Código Civil y Comercial en el Derecho Administrativo, Ed. Astrea, 2016

Fil: Gottschau, E. Patrizia. Procuración General de la Ciudad. Escuela de Formación en Abogacía Pública. Buenos Aires, ArgentinaTema: Administración Pública Digital / Coordinadores Pedro Aberastury y Juan Gustavo Corvalán. -- Sección III Reseñas bibliográficas