596 research outputs found

    Academic Primer Series: Five Key Papers for Consulting Clinician Educators.

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    INTRODUCTION: Clinician educators are often asked to perform consultations for colleagues. Invitations to consult and advise others on local problems can help foster great collaborations between centers, and allows for an exchange of ideas between programs. In this article, the authors identify and summarize several key papers to assist emerging clinician educators with the consultation process. METHODS: A consensus-building process was used to generate a list of key papers that describe the importance and significance of educational consulting, informed by social media sources. A three-round voting methodology, akin to a Delphi study, determined the most impactful papers from the larger list. RESULTS: Summaries of the five most highly rated papers on education consultation are presented in this paper. These papers were determined by a mixed group of junior and senior faculty members, who have summarized these papers with respect to their relevance for their peer groups. CONCLUSION: Five key papers on the educational consultation process are presented in this paper. These papers offer background and perspective to help junior faculty gain a grasp of consultation processes

    QCD thermodynamics with two flavors of Wilson quarks at N_t=6

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    We report on a study of hadron thermodynamics with two flavors of Wilson quarks on 12^3x6 lattices. We have studied the crossover between the high and low temperature regimes for three values of the hopping parameter, kappa=0.16, 0.17, and 0.18. At each of these values of kappa we have carried out spectrum calculations on 12^3x24 lattices for two values of the gauge coupling in the vicinity of the crossover in order to set an energy scale for our thermodynamics calculations and to determine the critical value of the gauge coupling for which the pion and quark masses vanish. For kappa=0.17 and 0.18 we find coexistence between the high and low temperature regimes over 1,000 simulation time units indicating either that the equilibration time is extremely long or that there is a possibility of a first order phase transition. The pion mass is large at the crossover values of the gauge coupling, but the crossover curve has moved closer to the critical curve along which the pion and quark masses vanish, than it was on lattices with four time slices. In addition, values of the dimensionless quantity T_c/m_rho are in closer agreement with those for staggered quarks than was the case at N_t=4. (A POSTSCRIPT VERSION OF THIS PAPER IS AVAILABLE BY ANONYMOUS FTP FROM sarek.physics.ucsb.edu (128.111.8.250) IN THE FILE pub/wilson_thermo.ps)Comment: 24 page

    Extracting excited states from lattice QCD: the Roper resonance

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    We present a new method for extracting excited states from a single two-point correlation function calculated on the lattice. Our method simply combines the correlation function evaluated at different time slices so as to ``subtract'' the leading exponential decay (ground state) and to give access to the first excited state. The method is applied to a quenched lattice study (volume = 24^3 x 64, beta = 6.2, 1/a = 2.55 GeV) of the first excited state of the nucleon using the local interpolating operator O = [uT C gamma5 d] u. The results are consistent with the identification of our extracted excited state with the Roper resonance N'(1440). The switching of the level ordering with respect to the negative-parity partner of the nucleon, N*(1535), is not seen at the simulated quark masses and, basing on crude extrapolations, is tentatively expected to occur close to the physical point.Comment: version to apper in Phys. Lett. B; additions in the presentation of the method; 3 references added; no change in the results and in the figure

    Hadron Spectrum in QCD with Valence Wilson Fermions and Dynamical Staggered Fermions at $6/g^2=5.6

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    We present an analysis of hadronic spectroscopy for Wilson valence quarks with dynamical staggered fermions at lattice coupling 6/g2=β=5.66/g^2 = \beta=5.6 at sea quark mass amq=0.01am_q=0.01 and 0.025, and of Wilson valence quarks in quenched approximation at β=5.85\beta=5.85 and 5.95, both on 163×3216^3 \times 32 lattices. We make comparisons with our previous results with dynamical staggered fermions at the same parameter values but on 16416^4 lattices doubled in the temporal direction.Comment: 32 page

    Initial Virological and Immunologic Response to Highly Active Antiretroviral Therapy Predicts Long-Term Clinical Outcome

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    Little is known about the long-term clinical outcomes for human immunodeficiency virus (HIV)-infected patients who have received highly active antiretroviral therapy (HAART). Determining factors associated with long-term clinical outcomes early in the course of treatment may allow modifications to be made for patients who are at a greater risk of treatment failure. To evaluate these factors, we studied 213 HIV-infected patients who had received HAART for at least 115 weeks. In the univariate analysis, virological response, which was measured as the change in virus load from baseline at month 3 of treatment, was the single best predictor of clinical outcome (relative hazard, 0.722; P = .001), independent of virological suppression. In the multivariate analysis, virological response and immunologic response, which was measured as an increase in CD4 cell count of >200 cells/mm^3, resulted in better prediction of clinical outcomes than did use of either variable alone (P = .02). Our results indicate that changes in virus load and immunologic response together are good predictors of clinical outcome and can be assessed after the initiation of HAART, which would allow clinicians to identify patients early in the course of therapy who are at greater risk of negative outcome

    Effects of BG9719 (CVT-124), an A1-Adenosine receptor antagonist, and furosemide on glomerular filtration rate and natriuresis in patients with congestive heart failure

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    AbstractOBJECTIVESTo determine the effects of furosemide and the selective A1adenosine receptor BG9719 on renal function in patients with congestive heart failure (CHF).BACKGROUNDStudies suggest that adenosine may affect renal function by various mechanisms, but the effects of blockade of this system in humans is unknown. In addition, the effects of a therapeutic dose of furosemide on glomerular filtration rate (GFR) and renal plasma flow (RPF) in heart failure patients are controversial.METHODSOn different days, 12 patients received placebo, BG9719 and furosemide. Glomerular filtration rate, RPF and sodium and water excretion were assessed immediately following drug administration.RESULTSGlomerular filtration rate was 84 ± 23 ml/min/1.73m2after receiving placebo, 82 ± 24 following BG9719 administration and a decreased (p < 0.005) 63 ± 18 following furosemide. Renal plasma flow was unchanged at 293 ± 124 ml/min/1.73m2on placebo, 334 ± 155 after receiving BG9719 and 374 ± 231 after receiving furosemide. Sodium excretion increased from 8 ± 8 mEq following placebo administration to 37 ± 26 mEq following BG9719 administration. In the six patients in whom it was measured, sodium excretion was 104 ± 78 mEq following furosemide administration.CONCLUSIONSNatriuresis is effectively induced by both furosemide and the adenosine A1antagonist BG9719 in patients with CHF. Doses of the two drugs used in this study did not cause equivalent sodium and water excretion but only furosemide decreased GFR. These data suggest that adenosine is an important determinant of renal function in patients with heart failure

    Effects of spatial size, lattice doubling and source operator on the hadron spectrum with dynamical staggered quarks

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    We have extended our previous study of the lattice QCD spectrum with 2 flavors of staggered dynamical quarks at 6/g2=5.66/g^2=5.6 and amq=0.025am_q=0.025 and 0.01 to larger lattices, with better statistics and with additional sources for the propagators. The additional sources allowed us to estimate the Δ\Delta mass and to measure the masses of all mesons whose operators are local in time. These mesons show good evidence for flavor symmetry restoration, except for the masses of the Goldstone and non-Goldstone pions. PCAC is observed in that mπ2mqm_\pi^2 \propto m_q, and fπf_\pi is estimated. Use of undoubled lattices removes problems with the pion propagator found in our earlier work. Previously we found a large change in the nucleon mass at a quark mass of amq=0.01am_q=0.01 when we increased the spatial size from 12 to 16. No such effect is observed at the larger quark mass, amq=0.025am_q=0.025. Two kinds of wall source were used, and we have found difficulties in getting consistent results for the nucleon mass between the two sources.Comment: 30 pages PostScript fil
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