Contemporary music education: the search for relevant strategy

The article considers the possibility of practical use of the theory of aesthetic sense of G. Cohen in musical pedagogy and ways to help maximize the self-realization of the creative person in modern societyСтатья рассматривает возможность практического использования теории эстетического чувства Г. Когена в музыкальной педагогике и пути, помогающие максимальной самореализации творческого человека в современном социум

IMPORTANCE OF MEDIA EDUCATION FOR YOUNG PEOPLE IN THE FIELD OF FOOD BIOTECHNOLOGY

Influence of the media on the market of biotechnological products has been studied. Awareness of citizens about food technologies and genetically modified foods has been analysed. Position of state institutions and the scientific community regarding genetic engineering, broadcast through the media, indirectly affects the attitude of young people to genetically modified foods. The results of a sociological survey of young people and an analysis of media materials have revealed the importance of media resources in shaping public opinion. The study has clarified that among young people the attitude to genetically modified foods is largely determined by expert assessments of public people and advertising that creates the image of the product. The relevance of the issue lies in understanding the importance of informing the population in matters of biotechnology in general and media education of the youth audience in particular. The conducted study on the attitude of young people to genetically modified products and food bioengineering has assisted in revealing the importance of the issue raised by the authors and allowed them to formulate recommendations on providing a comprehensive program to increase youth media literacy in food biotechnology. The proposals aimed at providing a comprehensive program for improving media literacy are related to the search for ways to increase the level of public confidence in genetically modified foods

Assessment of Factors Influencing the Innovation Potential of Vertically Integrated Companies in a Macroregion

Due to the globalisation of the world economy and development of transnational corporations, vertically integrated companies have to use a wide range of innovation opportunities spanning the entire value chain in order to maintain market positions. Thus, such companies need to constantly and timely monitor changes influencing the innovation potential. The study proposes a new methodology for assessing the innovation potential of vertically integrated companies (VICs) and affecting factors. The implementation of the principle of continuity across the value chains of vertically integrated companies ensures the integrity and reliability of research results. Statistical data of seven VICs of the Volga Federal District for 2017 were analysed. Using the proposed methodology, we determined aggregate factors, ranked them and revealed their stimulating and disincentive effects on the innovation potential of VICs. Additionally, the study identified mechanisms for the efficient use of such potential across the value chains for strengthening the socio-economic development of regions. The analysis was performed based on the integrated use of structural, functional, generalisation, correlation and regression, statistical and economic, and expert assessment methods. It explained the distribution of factors and their correlation dependencies. The quantitative evaluation of presented factors demonstrated their varying impact on the innovation potential of vertically integrated companies. The research results can be used for developing regional strategies aimed at the improvement of company performance and economic crisis resolution

Assessment of Factors Influencing the Innovation Potential of Vertically Integrated Companies in a Macroregion

Due to the globalisation of the world economy and development of transnational corporations, vertically integrated companies have to use a wide range of innovation opportunities spanning the entire value chain in order to maintain market positions. Thus, such companies need to constantly and timely monitor changes influencing the innovation potential. The study proposes a new methodology for assessing the innovation potential of vertically integrated companies (VICs) and affecting factors. The implementation of the principle of continuity across the value chains of vertically integrated companies ensures the integrity and reliability of research results. Statistical data of seven VICs of the Volga Federal District for 2017 were analysed. Using the proposed methodology, we determined aggregate factors, ranked them and revealed their stimulating and disincentive effects on the innovation potential of VICs. Additionally, the study identified mechanisms for the efficient use of such potential across the value chains for strengthening the socio-economic development of regions. The analysis was performed based on the integrated use of structural, functional, generalisation, correlation and regression, statistical and economic, and expert assessment methods. It explained the distribution of factors and their correlation dependencies. The quantitative evaluation of presented factors demonstrated their varying impact on the innovation potential of vertically integrated companies. The research results can be used for developing regional strategies aimed at the improvement of company performance and economic crisis resolution

Risk factors and diagnostic value of urinary N-terminal pro-brain natriuretic peptide for verification of heart failure in human immunodeficiency virus-infected patients

Aim. To determine the risk factors and diagnostic value of urinary N-terminal probrain natriuretic peptide (NT-proBNP) for verification of heart failure in human immunodeficiency virus (HIV)-infected patientsMaterial and methods. This cross-sectional screening clinical trial included 115 HIV-infected patients who were hospitalized during 24 months. The patients were divided into 2 groups, depending on the data suggestive of HF and the blood and urinary NT-proBNP concentration. So, group 1 included 69 HIV-infected patients with HF symptoms and increased blood and urinary NTproBNP, while group 2 — 46 HIV-infected patients not meeting HF criteria. NTproBNP concentration was determined on Immulite 1000 Immunoassay System (DPC, USA) in blood plasma and frozen urine using Vector Best reagents (Russia).Results. Correlation analysis revealed a significant direct moderate correlation between blood and urinary NT-proBNP in the entire cohort of studied patients (r=0,367; p<0,05). Urinary NT-proBNP ≥8,6 pg/ml ml is diagnostic for HF verification in HIV-infected patients. Significant differences between the groups were obtained in the incidence of ventricular arrhythmias, viral hepatitis B and C, liver cirrhosis, infective endocarditis, other inflammatory diseases, thrombocytopenia, left ventricular (LV) diastolic dysfunction and its severity. In addition, there were differences in LV mass index, left atrial volume index, incidence of LV hypertrophy and left atrial enlargement, concentration of hemoglobin and CD4 cells <200 in 1 µl. The preserved LV ejection fraction was detected significantly more often (p<0,001). Conclusion. In HIV-infected patients, blood plasma and urinary NT-proBNP concentration correlates with each other. Urinary NT-proBNP ≥8,6 pg/ml is diagnostic for HF verification in HIV-infected patients. Risk factors and features of developing HF, estimated by NT-proBNP concentration in frozen urine in HIV-infected patients, are comparable to data obtained from blood plasma NTproBNP

Historical and Legal Aspects of Participation of the Prosecutor in Civil Proceedings in the Russian Federation

The article is devoted to the study of the development of the legal framework of participation of the Prosecutor in civil cases by the courts since the establishment of the posts of prosecutors in 1722 also Dedicated two new historical conditions, when the prosecution was re-established and empowered to participate in the consideration of cases in courts. Analyzed the reasons for the creation of the prosecution, the powers of prosecutors, the relationship of prosecutors and courts

Contribution of inflammation to heart failure development in human immunodeficiency virus-infected patients

Aim. To determine the peculiarities of heart failure (HF) development in human immunodeficiency virus (HIV)-infected patients, depending on the blood concentration of C-reactive protein (CRP).Material and methods. This cross-sectional screening clinical trial included 100 patients hospitalized with HIV infection and a history of HF for 28 months. The patients were divided into 2 groups depending on blood CRP concentration. The cut-off point was CRP of 15 mg/l. The first group included 37 HIV-infected patients with HF and blood CRP <15 mg/l, while the second group — 63 HIV-infected patients with HF and CRP concentration ≥15 mg/l. The inclusion criteria were HIV infection and prior HF, stable medical state, taking into account the underlying disease that required hospitalization. The study did not include patients with acute cardiovascular diseases within prior 3 months, acute decompensated and acute heart failure, cancer, infectious diseases, conditions that required surgical intervention. N-terminal pro-brain natriuretic peptide (NT-proBNP) was determined in all patients.Results. Correlation analysis revealed a strong inverse relationship between the blood concentrations of NT-proBNP and CRP (r=-0,639; p<0,005). A ROC curve revealed the most optimal cut-off threshold of 9,8 mg/l (AUC=0,796, p<0,05), which ensures sensitivity of 92,9% (p<0,05) and specificity of 57,6% (p<0,05). The odds ratio (OR) of an increase in NT-proBNP >450 pg/ml, and hence the risk of acute decompensated HF in the presence of a CRP concentration of 1-9,8 mg/l in HIV-infected patients with HF was 44,73 (95% CI=8,62;311,10), while relative risk (RR) — 18,73 (95% CI=4,94;112,94). In the presence of in hospital inflammatory diseases and CRP ≥15 mg/l in HIV-infected patients and prior HF, the RR of acute decompensated HF is reduced by 88% (RR=0,12, 95% CI=0,03-0,33).Conclusion. CRP values from 1 to 9,8 mg/l in HIV-infected patients with HF are predictors of its severity, characterized by a higher incidence of HF with reduced ejection fraction, diastolic dysfunction and left ventricular hypertrophy without significant differences with patients who have CRP >9,8 mg/l. CRP concentration >9,8 mg/l in HIV-infected patients and prior HF indicates the development of an inflammatory process, and not a worsening of the HF course

ORGANIZATION OF MEDICAL AID DURING ANTHRAX OUTBREAK IN YAMALO-NENETS AUTONOMOUS DISTRICT IN 2016

The efficiency and timeliness of medical care of infectious patients are largely determined by the promptness of diagnosis and the rational organization of medical sorting of patients and contact persons. In 2016 there were 36 anthrax cases in the Yamal. In the immediate area of the epidemic were 327 people, including 135 children, in the endangered area – 539 people, including 217 children. Organization of medical care for patients and contact persons was accompanied by objective difficulties associated with the vastness of the territory under threat of infection spread, the presence of atypical and rare clinical forms of anthrax. Тhe article presents the analysis of actions for rendering of medical aid to patients with anthrax in the Yamal in 2016, and the proposed algorithms in medical triage and the organization of the emergency unit

Improving the management technique of logistics planning in the supply chain

The multidimensionality of transformations that take place, the diversity of destabilizing factors in the environment reduce reliability, sustainability, efficiency of both logistics processes and the entire production and economic activity, and they need their modern economic reflection. The successful activity in the unstable economic environment is impossible without proper strategic analysis and the formation of the effective management system that requires the search for new techniques, the development of logistics-oriented concepts, management approaches to logistics processes that can ensure the goals achievement under the continuous systemic development and disturbance flow. The goal of the research is to improve the technique and develop a management model for logistics processes, considering the effect of the disturbance flow. In accordance with the goal, it is necessary to solve the following scientific problems: to reveal the patterns of logistics processes for the formation of a signal system on management points within the framework of management structures; to develop components of the management technique for logistics processes, taking into account the disturbance flow; to systematize and supplement the principles of logistics processes for the formation of the rational totality of components in the management technique. Thus, the implementation of the proposed management technique for logistics processes will lead to the formation of optimal management impacts within each element, subsystem and the entire structure of the supply chain, ensuring the sustainable development vector at each time period and achieving the goals set under the influence of the disturbance flow, adaptability, flexibility and efficiency of processes

New palynological data for Toarcian (Lower Jurassic) deep-marine sandstones of the Western Caucasus, southwestern Russia

Information on Jurassic palynomorphs from the Greater Caucasus is potentially of great importance, but its availability to the international research community is severely limited. New palynological data for Toarcian deposits of the Western Caucasus are recorded in the present paper. Particularly, dinoflagellate cysts are described for the first time from the Bagovskaja Formation; palynomorphs are found in sandstone levels within this unit. The most representative assemblage includes pollen (with predominant bisaccate pollen), spores (Cyathidites being commonest), and dinoflagellate cysts amongst which the predominant taxon is Nannoceratopsis spiculata. The dinocyst assemblage implies a late Toarcian age for the upper part of the Bagovskaja Formation. On the basis of these new palynostratigraphical results, the range of the formation is extended; previously, only the lower part had been dated on ammonite evidence