352 research outputs found

    The Case of Some Inhabitants of East Florida, 1767-1785

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    In London, in the spring of 1823, a young clerk named Daniel, in the House of Delcroix, Perfumers, received word that Mrs. Isabella Stout, widow of Daniel Stout of Nassau in the Bahamas, had been searching the length and breadth of England for him, as he was heir to part of the estate left by his aunt, Mary Rolph Stout of Nassau. The Colonial Secretary for the Bahamas, Mr. Samuel Nesbit, had also been searching, and about the same time located young Daniel and other members of his motherā€™s family, the Rolphs of Canterbury, who empowered Nesbit to receive their legacies

    Assessment of causal link between psychological factors and symptom exacerbation in inflammatory bowel disease: a systematic review utilising Bradford Hill criteria and meta-analysis of prospective cohort studies

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    BACKGROUND: Psychological stress is a prevalent factor in inflammatory bowel disease (IBD) with detrimental effects on patients' quality of life and possibly disease course. Although the aetiology of symptom exacerbation in IBD has been explored, determining any causation between psychological stress and symptom worsening remains challenging and requires a methodologically rigorous approach. AIM: The aim of this systematic review with meta-analysis was to determine a causal relationship between psychological stress and symptom exacerbation in IBD, subsequently utilising Bradford Hill's criteria (approach never used in this topic area before) to evaluate the likelihood of causal associations. METHODS: Medline, EMBASE, CINAHL and PsycInfo were searched for relevant studies up to July 20, 2019. Data extraction and quality appraisal were performed by two independent reviewers. Results of all retained papers were presented as a narrative synthesis. A random-effect meta-analysis was conducted on studies meeting the criteria for meta-analysis. Bradford Hill criteria were applied to assess the causality of the relationship between all psychological factors and symptom exacerbation. RESULTS: The searches yielded 2472 potential articles. Nineteen clinical prospective cohort studies were eligible for the narrative review with five suitable for the meta-analysis. Meta-analysis showed depression, anxiety and perceived stress did not have a statistically significant association with an increased risk of symptom exacerbation. Four of the Bradford Hill criteria were met which indicates that there is weak to moderate evidence of a causal association between all the psychological factors and disease activity. Inconsistent results and a dearth of studies using the same tools for measuring psychological factors suggest the need for more research to be done to facilitate more conclusive findings. CONCLUSIONS: This original review utilising Bradford Hill criteria in addition to meta-analysis to evaluate the causality of relationship between psychological factors and symptom exacerbation in IBD provides evidence that psychological factors have a weak to moderate causal involvement in IBD symptom exacerbation. However, when combining this finding with the outcomes of the meta-analysis, we can say that the results were inconclusive. Interventions to reduce the associated psychological impact should be part of the treatment plan for patients with IBD. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42012003143

    Burnout in sport: A systematic review

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    The purpose of the present review was to provide an up-to-date summary of the burnout-in-sport literature. The last published reviews were in 1989 (Fender) and 1990 (Dale & Weinberg). In order to appreciate the status of current knowledge and understanding and to identify potential future directions, the authors conducted a synthesis of published work using a systematic-review methodology. Findings comprised 3 sections: sample characteristics, correlates, and research designs and data collection. A total of 58 published studies were assessed, most of which focused on athletes (n = 27) and coaches (n = 23). Correlates were grouped into psychological, demographic, and situational factors and were summarized as positively, negatively, indeterminate, and nonassociated with burnout. Self-report measures and cross-sectional designs have dominated research. The authors conclude by summarizing the key findings in the literature and highlighting the gaps that could be filled by future research

    An assessment of self-reported physical activity instruments in young people for population surveillance: Project ALPHA

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    <p>Abstract</p> <p>Background</p> <p>The assessment of physical activity is an essential part of understanding patterns and influences of behaviour, designing interventions, and undertaking population surveillance and monitoring, but it is particularly problematic when using self-report instruments with young people. This study reviewed available self-report physical activity instruments developed for use with children and adolescents to assess their suitability and feasibility for use in population surveillance systems, particularly in Europe.</p> <p>Methods</p> <p>Systematic searches and review, supplemented by expert panel assessment.</p> <p>Results</p> <p>Papers (n = 437) were assessed as potentially relevant; 89 physical activity measures were identified with 20 activity-based measures receiving detailed assessment. Three received support from the majority of the expert group: Physical Activity Questionnaire for Children/Adolescents (PAQ-C/PAQ-A), Youth Risk Behaviour Surveillance Survey (YRBS), and the Teen Health Survey.</p> <p>Conclusions</p> <p>Population surveillance of youth physical activity is strongly recommended and those involved in developing and undertaking this task should consider the three identified shortlisted instruments and evaluate their appropriateness for application within their national context. Further development and testing of measures suitable for population surveillance with young people is required.</p

    Device-measured Desk-based Occupational Sitting Patterns and Stress (hair cortisol and perceived stress)

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    Background: Stress and poor mental health are significant issues in the workplace and are a major cause of absenteeism and reduce productivity. Understanding what might contribute towards employee stress is important for managing mental health in this setting. Physical activity has been shown to be beneficial to stress but less research has addressed the potential negative impact of sedentary behaviour such as sitting. Therefore, the aim of this study was to assess the relationship between device-measured occupational desk-based sitting patterns and stress (hair cortisol levels (HCL), as a marker of chronic stress and self-reported perceived stress (PS)). Methods: Employees were recruited from four workplaces located in Central Scotland with large numbers of desk-based occupations. Seventy-seven participants provided desk-based sitting pattern data (desk-based sitting time/day and desk-based sit-to-stand transitions/day), a hair sample and self-reported perceived stress. HCL were measured using enzyme-linked immunosorbent assay and PS using the Cohen Self-Perceived Stress Scale. Linear regression models were used to test associations between desk-based sitting time/day, desk-based sit-to-stand transitions/day, HCL and PS. Results: There were no associations between any of the desk-based sitting measures and either HCL or PS. Conclusion. Desk-based sitting patterns in the workplace may not be related to stress when using HCL as a biomarker or PS. The relationship between sitting patterns and stress therefore requires further investigation

    A systematic review and narrative summary of family-based smoking cessation interventions to help adults quit smoking

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    Background: Smoking is the most significant preventable cause of morbidity and early mortality in the world. The family is an influential context in which smoking behaviour occurs. Methods: A systematic review and narrative summary of family-based interventions to help adults quit smoking was conducted. Results: Eight controlled trials were included. Risk of bias was high. The smoking-related outcome of the intervention was self-reported smoking status/abstinence, validated by objective measures (including saliva thiocynate or breath carbon monoxide). Follow-up ranged from six weeks to five years. The main target groups were: pregnant women (1), pregnant women who smoked (2), men at risk of cardiovascular disease (2), adult smokers (1), parents who smoked (1) and couples who both smoked (1). Interventions included family members but most did not go further by drawing on family, systemic or relational theories to harness the influence of family on smoking behaviour. Only three studies directly compared the effects on smoking behaviour of a family-based (i.e. interventions that involve a member of the family) versus an individual-based (i.e. interventions that use behaviour change techniques that focus on the individual) intervention. None of these studies found significant differences between groups on the smoking behaviour of the main target group. Conclusions: We have yet to develop family-based smoking cessation interventions that harness or re-direct the influence of family members on smoking behaviour in a positive way. Thus, it is likely that individualised-approaches to smoking cessation will prevail.Publisher PDFPeer reviewe

    Physiological and psychological outcomes of high intensity interval training in patients with heart failure compared to moderate continuous training and usual care: a systematic review with meta analysis.

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    An important component of secondary prevention of CVD (including HF) is comprehensive cardiac rehab, including exercise. Novel, individualised approaches are needed to increase uptake and adherence to exercise programmes. One area offering potential is HIIT. HIIT has been shown to be both safe and effective for improving cardiovascular fitness in both coronary artery disease and HF patients. The objective of this study was to provide a current and up-to-date evaluation of the physiological and psychological outcomes of HIIT in patients with HF, compared to MCT and UC. A secondary objective was to perform sub-group analyses comparing short and long HIIT protocols. A systematic review and meta-analysis of randomised controlled trials was undertaken. Medline, Embase, Scopus, CINAHL and SportDISCUS were searched up to July 2022. Trials were included if they carried out a HIIT intervention (defined at intensity ā‰„ 80% peak HR or ā‰„ 80% VO2peak) in HF patients (HFpEF or HFrEF) for at least 6 weeks. Comparator group was UC or MCT. HIIT was shown to be superior to MCT and UC for improving VO2peak (HIIT mean improvement 3.1mL.kg-1min-1). HITT was superior to MCT and UC for improving LVEF (HIIT mean improvement 5.7%). HIIT was superior to MCT and UC for improving HRQoL, using the MLHFQ (HIIT mean point change of -12.8). Subgroup analysis showed no difference between long and short HIIT. The study therefore concluded that HIIT improves VO2peak, LVEF and HRQoL in patients with HF, with the improvements seen in VO2peak and LVEF being superior in HIIT compared to MCT and UC

    The effectiveness of an annual nationally delivered workplace step count challenge on changing step counts:Findings from four years of delivery

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    Paths for Allā€™s 8-week online Workplace Step Count Challenge (SCC) is a flagship program of Scotlandā€™s National Walking Strategy. The aim of this study was to examine changes in step counts throughout the duration of the SCC, across four years of delivery. Participants were those who registered for the 2015ā€“2018 SCCs, and reported demographic data at registration. Participants self-reported their device-measured step count for each day of the SCC. Following data screening, mean daily steps for each week were calculated. Linear mixed models (R nlme procedure), controlling for the within subject nature of the step count measure, were used to explore changes in steps over time. Gender and age group (< 45 years; ā‰„ 45 years) were entered into a subsequent model. Separate models were created for each year of the SCC and for all years combined. Participants (n = 10,183) were predominantly women (76.8%), aged < 45 (54.6%) and ā‰„ 45 years. In general, steps increased each week compared to week 1 (p < 0.001), with a significant increase evident at all but seven of 28 data points. Across the four years of SCC, the increase in steps at week 8 compared to week 1 ranged from 506 to 1223 steps per day, making a substantial contribution to the recommended physical activity levels for health. There was no consistent age or gender effect. The findings provide support for the continued investment in such workplace interventions

    A citizen science study of short physical activity breaks at school:Improvements in cognition and wellbeing with self-paced activity

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    Background School-based physical activity and running programmes, such as The Daily Mileā„¢, are increasing in popularity globally. The aim of this research was to examine the acute impact of such classroom physical activity breaks on cognition and affective wellbeing. Methods A total of 5463 school pupils from 332 schools took part in a citizen science project with a repeated measures design. They completed tasks of cognition (inhibition, verbal, and visuo-spatial working memory) and the Childrenā€™s Feeling Scale and Felt Arousal Scale before and after three different outdoor activities: a classroom break of 15ā€‰min of self-paced activity, a near maximal exhaustion activity (the bleep test), and a no-exercise control group where pupils sat or stood outside. Wellbeing and fitness were examined as mediators of the relationship between outdoor activity and cognition. Results Fifteen minutes of self-paced outdoor activity was beneficial for pupilsā€™ cognition and wellbeing in comparison to both other activities (Cohenā€™s d effect sizes ranging from 0.04 to 0.22; small). The relationship with cognition was not mediated by participantsā€™ fitness level and was only partially mediated by wellbeing. Change scores for alertness were higher after the bleep test compared to the control activity but similar for all other outcomes. Conclusions Taking a break from the classroom to complete 15ā€‰min of self-paced physical activity should be considered a worthwhile activity by class teachers, school management, and policymakers. Additionally, more intense physical activity should not be considered to be detrimental

    Barriers and facilitators to participating in cardiac rehabilitation and physical activity in a remote and rural population : A cross-sectional survey

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    The authors are grateful to the staff of the Research, Development and Innovation offices, who assisted in the distribution and collection of questionnaires, and the Cardiac Rehabilitation staff. The authors would like to thank all patients involved in this study. Funding: DC was funded by Highlands and Islands Enterprise (project number HMS 9353763)Peer reviewedPublisher PD
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