A system of three transiting super-Earths in a cool dwarf star

We present the detection of three super-Earths transiting the cool star LP415-17, monitored by K2 mission in its 13th campaign. High resolution spectra obtained with HARPS-N/TNG showed that the star is a mid-late K dwarf. Using spectral synthesis models we infer its effective temperature, surface gravity and metallicity and subse- quently determined from evolutionary models a stellar radius of 0.58 R Sun. The planets have radii of 1.8, 2.6 and 1.9 R Earth and orbital periods of 6.34, 13.85 and 40.72 days. High resolution images discard any significant contamination by an intervening star in the line of sight. The orbit of the furthest planet has radius of 0.18 AU, close to the inner edge of the habitable zone. The system is suitable to improve our understanding of formation and dynamical evolution of super-Earth systems in the rocky - gaseous threshold, their atmospheres, internal structure, composition and interactions with host stars.Comment: Accepted for publication in MNRAS Letter

Temporal changes of the flare activity of Proxima Cen

We study temporal variations of the emission lines of Halpha, Hepsilon, H and K Ca II, D1 and D2 Na I, 4026 and 5876 A He I in the HARPS spectra of Proxima Centauri across an extended time of 13.2 years, from May 27, 2004, to September 30, 2017. Aims. We analyse the common behaviour and differences in the intensities and profiles of different emission lines in flare and quiet modes of Proxima activity. Methods. We compare the pseudo-equivalent widths (pEW) and profiles of the emission lines in the HARPS high-resolution (R ~ 115,000) spectra observed at the same epochs. Results. All emission lines show variability with a timescale of at least 10 min. The strength of all lines except He I 4026 A correlate with \Halpha. During strong flares the `red asymmetry' appears in the Halpha emission line indicating the infall of hot condensed matter into the chromosphere with velocities greater than 100 km/s disturbing chromospheric layers. As a result, the strength of the Ca II lines anti-correlates with Halpha during strong flares. The He I lines at 4026 and 5876 A appear in the strong flares. The cores of D1 and D2 Na I lines are also seen in emission. During the minimum activity of Proxima Centauri, Ca II lines and Hepsilon almost disappear while the blue part of the Na I emission lines is affected by the absorption in the extending and condensing flows. Conclusions. We see different behaviour of emission lines formed in the flare regions and chromosphere. Chromosphere layers of Proxima Cen are likely heated by the flare events; these layers are cooled in the `non-flare' mode. The self-absorption structures in cores of our emission lines vary with time due to the presence of a complicated system of inward and outward matter flows in the absorbing layers.Comment: 22 pages, 12 Figures, accepted by A

Dynamic analysis using finite elements to calculate the critical wear section of the contact wire in suburban railway overhead conductor rails

The purpose of this study is to determine the critical wear levels of the contact wire of the catenary on metropolitan lines. The study has focussed on the zones of contact wire where localised wear is produced, normally associated with the appearance of electric arcs. To this end, a finite element model has been developed to study the dynamics of pantograph-catenary interaction. The model includes a zone of localised wear and a singularity in the contact wire in order to simulate the worst case scenario from the point of view of stresses. In order to consider the different stages in the wire wear process, different depths and widths of the localised wear zone were defined. The results of the dynamic simulations performed for each stage of wear let the area of the minimum resistant section of the contact wire be determined for which stresses are greater than the allowable stress. The maximum tensile stress reached in the contact wire shows a clear sensitivity to the size of the local wear zone, defined by its width and depth. In this way, if the wear measurements taken with an overhead line recording vehicle are analysed, it will be possible to calculate the potential breakage risk of the wire. A strong dependence of the tensile forces of the contact wire has also been observed. These results will allow priorities to be set for replacing the most critical sections of wire, thereby making maintenance much more efficient. The results obtained show that the wire replacement criteria currently borne in mind have turned out to be appropriate, although in some wear scenarios these criteria could be adjusted even more, and so prolong the life cycle of the contact wire

Abundance trend with condensation temperature for stars with different Galactic birth places

During the past decade, several studies reported a correlation between chemical abundances of stars and condensation temperature (also known as Tc trend). However, the real astrophysical nature of this correlation is still debated. The main goal of this work is to explore the possible dependence of the Tc trend on stellar Galactocentric distances, Rmean. We used high-quality spectra of about 40 stars observed with the HARPS and UVES spectrographs to derive precise stellar parameters, chemical abundances, and stellar ages. A differential line-by-line analysis was applied to achieve the highest possible precision in the chemical abundances. We confirm previous results that [X/Fe] abundance ratios depend on stellar age and that for a given age, some elements also show a dependence on Rmean. When using the whole sample of stars, we observe a weak hint that the Tc trend depends on Rmean. The observed dependence is very complex and disappears when only stars with similar ages are considered. To conclude on the possible dependence of the Tc trend on the formation place of stars, a larger sample of stars with very similar atmospheric parameters and stellar ages observed at different Galactocentric distances is neededComment: Accepted by A&

Rapid Phenotype-Driven Gene Sequencing with the NeoSeq Panel: A Diagnostic Tool for Critically Ill Newborns with Suspected Genetic Disease

New genomic sequencing techniques have shown considerable promise in the field of neonatology, increasing the diagnostic rate and reducing time to diagnosis. However, several obstacles have hindered the incorporation of this technology into routine clinical practice. We prospectively evaluated the diagnostic rate and diagnostic turnaround time achieved in newborns with suspected genetic diseases using a rapid phenotype-driven gene panel (NeoSeq) containing 1870 genes implicated in congenital malformations and neurological and metabolic disorders of early onset (<2 months of age). Of the 33 newborns recruited, a genomic diagnosis was established for 13 (39.4%) patients (median diagnostic turnaround time, 7.5 days), resulting in clinical management changes in 10 (76.9%) patients. An analysis of 12 previous prospective massive sequencing studies (whole genome (WGS), whole exome (WES), and clinical exome (CES) sequencing) in newborns admitted to neonatal intensive care units (NICUs) with suspected genetic disorders revealed a comparable median diagnostic rate (37.2%), but a higher median diagnostic turnaround time (22.3 days) than that obtained with NeoSeq. Our phenotype-driven gene panel, which is specific for genetic diseases in critically ill newborns is an affordable alternative to WGS and WES that offers comparable diagnostic efficacy, supporting its implementation as a first-tier genetic test in NICUs

Dimensions of Religiousness and Cancer Screening Behaviors among Church-Going Latinas

Churches are a promising setting through which to reach Latinas with cancer control efforts. A better understanding of the dimensions of religiousness that impact health behaviors could inform efforts to tailor cancer control programs for this setting. The purpose of this study was to explore relationships between dimensions of religiousness with adherence to cancer screening recommendations among church-going Latinas. Female Spanish-speaking members, aged 18 and older from a Baptist church in Boston, Massachusetts (N = 78), were interviewed about cancer screening behaviors and dimensions of religiousness. We examined adherence to individual cancer screening tests (mammography, Pap test, and colonoscopy), as well as adherence to all screening tests for which participants were age-eligible. Dimensions of religiousness assessed included church participation, religious support, active and passive spiritual health locus of control, and positive and negative religious coping. Results showed that roughly half (46 %) of the sample had not received all of the cancer screening tests for which they were age-eligible. In multivariate analyses, positive religious coping was significantly associated with adherence to all age-appropriate screening (OR = 5.30, p \u3c .01). Additional research is warranted to replicate these results in larger, more representative samples and to examine the extent to which enhancement of religious coping could increase the impact of cancer control interventions for Latinas

Integrative analyses of speciation and divergence in Psammodromus hispanicus (Squamata: Lacertidae)

BackgroundGenetic, phenotypic and ecological divergence within a lineage is the result of past and ongoing evolutionary processes, which lead ultimately to diversification and speciation. Integrative analyses allow linking diversification to geological, climatic, and ecological events, and thus disentangling the relative importance of different evolutionary drivers in generating and maintaining current species richness.ResultsHere, we use phylogenetic, phenotypic, geographic, and environmental data to investigate diversification in the Spanish sand racer (Psammodromus hispanicus). Phylogenetic, molecular clock dating, and phenotypic analyses show that P. hispanicus consists of three lineages. One lineage from Western Spain diverged 8.3 (2.9-14.7) Mya from the ancestor of Psammodromus hispanicus edwardsianus and P. hispanicus hispanicus Central lineage. The latter diverged 4.8 (1.5-8.7) Mya. Molecular clock dating, together with population genetic analyses, indicate that the three lineages experienced northward range expansions from southern Iberian refugia during Pleistocene glacial periods. Ecological niche modelling shows that suitable habitat of the Western lineage and P. h. edwardsianus overlap over vast areas, but that a barrier may hinder dispersal and genetic mixing of populations of both lineages. P. h. hispanicus Central lineage inhabits an ecological niche that overlaps marginally with the other two lineages.ConclusionsOur results provide evidence for divergence in allopatry and niche conservatism between the Western lineage and the ancestor of P. h. edwardsianus and P. h. hispanicus Central lineage, whereas they suggest that niche divergence is involved in the origin of the latter two lineages. Both processes were temporally separated and may be responsible for the here documented genetic and phenotypic diversity of P. hispanicus. The temporal pattern is in line with those proposed for other animal lineages. It suggests that geographic isolation and vicariance played an important role in the early diversification of the group, and that lineage diversification was further amplified through ecological divergence

Heterogeneous Photocatalytic Degradation of Ibuprofen Over TiO2–Ag Supported on Activated Carbon from Waste Tire Rubber

In recent years it has been discovered that some common use medicines, such as ibuprofen and other nonsteroidal anti-inflammatory drugs, are found in water sources in concentrations that have the potential to affect aquatic organisms. On the other hand, waste used tires are a massive problem for the environment due to the leaching of toxic compounds to soils and water. Also, the exposition to environmental conditions can make them sources of vectors like mosquitoes. In this work, three activated carbon (AC) catalysts derived from waste tire rubber, titanium dioxide and silver were synthesized using the sol–gel method. Morphological characterizations such as SEM and TEM were performed in which, the agglomeration of titanium particles and silver crystals on the surface of the AC is evident. In the XRD analysis, the presence of elemental silver nanoparticles was detected. In the diffuse reflectance spectroscopy analysis, the decrease in the titanium band gap, as well as activity in the visible spectrum, was observed. The photocatalytic tests were performed at pH 3 and 7 in the presence of UV/Vis radiation. These tests show that there are differences between the catalyst in both, UV and visible regions. Adsorption is a major phenomenon for the removal of ibuprofen, followed by photolytic decomposition. In visible spectra, the catalysts show a good performance for the removal of ibuprofen