A computationally efficient simulation method for optimizing front contacts of concentrator multijunction solar cells

In this work, a novel multidiode model is proposed for optimizing the front grid of multijunction solar cells operating under concentration conditions. The model allows for quickly exploring the maximum achievable efficiency under a wide range of operating conditions and design parameters such as the redirecting capability, period and width of the fingers, the light concentration, and the metal and emitter sheet resistivity. The proposed multidiode model shows to be consistent with experimental data and with more complex modeling approaches such as the simulation program with integrated circuit emphasis (SPICE) model

Efecto de la dl-metionina y la hidroxi-análoga de la dl-metionina sobre la productividad en pollos de engorde

La metionina (Met) es el aminoácido (AA) más limitante en dietas comerciales para avicultura. Durante los últimos 25 años, la DL-Met y la forma líquida del hidroxi análogo de la DL-Metionina ácido libre (MHA-FA) han sido las fuentes propuestas como suplementación en condiciones comerciales. Niveles excesivos de proteína bruta aumentan el coste y pueden perjudicar el desarrollo de las aves (Binder y Lemme, 2007). El objetivo de este ensayo fue evaluar los efectos de niveles crecientes de dos fuentes de Metionina sintética en pollos de engorde de 1 a 34 días de edad

Influence of energy concentration and feed form of the diet on growth performance and digestive traits of brown egg-laying pullets from 1 to 120 days of age

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Eukaryotic elongation factor 2 controls TNF-alpha translation in LPS-induced hepatitis

Bacterial LPS (endotoxin) has been implicated in the pathogenesis of acute liver disease through its induction of the proinflammatory cytokine TNF-alpha. TNF-alpha is a key determinant of the outcome in a well-established mouse model of acute liver failure during septic shock. One possible mechanism for regulating TNF-alpha expression is through the control of protein elongation during translation, which would allow rapid cell adaptation to physiological changes. However, the regulation of translational elongation is poorly understood. We found that expression of p38gamma/delta MAPK proteins is required for the elongation of nascent TNF-alpha protein in macrophages. The MKK3/6-p38gamma/delta pathway mediated an inhibitory phosphorylation of eukaryotic elongation factor 2 (eEF2) kinase, which in turn promoted eEF2 activation (dephosphorylation) and subsequent TNF-alpha elongation. These results identify a new signaling pathway that regulates TNF-alpha production in LPS-induced liver damage and suggest potential cell-specific therapeutic targets for liver diseases in which TNF-alpha production is involved

Contribución al estudio de las comunidades rupícolas de la Cheilanthetalia marantho-maderensis y Androsacetalia vandellii en la Península Ibérica

An study on the Iberian Peninsula rocks comunities it is going on with dominantes by several species of the genus Cheilaruhes and Notholaena, from these the new associations of the Phagnalo saxatile-Cheilanthion maderensis alliance (Cheilanthetalia maranto-maderensis, Asplenietea trichomanis): Notholaeno marantae-Cheilanthetum guanchicae are proposed the first distinctive of the Bermejense Subsector (Rondefio Sector, Betica chorological Province) and the second Cheilantho maderensis-Cosentinietum velleae with is basically of the Betic distribution. Based on the bibliography and on our own data, a comparative analysis of the casmofitic comunities on the Cheilanthetalia maranto-maderensis order and Androsacetalia vandellii order are presented, taking into account their relationships with Phagnalo-Rumicetea indurati. Forthermore from this last one the association Phalacro- carpoSaxifragetum continent alis is also described.Se lleva a cabo un estudio de las comunidades rupícolas ibéricas presididas por diversas especies de los géneros Cheilanthes y Notholaena, proponiéndose dos nuevas asociaciones de la alianza Phagnalo saxatile-Cheilanthion maderensis (Cheilanthetalia maranto-maderensis, Asplenietea trichomanis): Notholaeno marantae-Cheilanthetum guanchicae, propia del Subsector Bermejense (Sector Ronderlo, Provincia Bética) y Cheilantho maderensis-Cosentinietum velleae, de distribución fundamentalmente bética. Con datos propios y otros bibliográficos, se hace un análisis crítico, a la vez que un estudio comparado, de las comunidades casmofíticas incluidas en los órdenes Cheilanthetalia maranto-maderensis (termomediterránea y silicíbasícola) y Androsacetalia vandellii (montana y supracrioro mediterránea, silicícola), analizando sus relaciones con las comunidades comofíticas de la Phagnalo-Rumicetea indurati. De esta última se describe la asociación Phalacrocarpo-Saxifragetum continentalis (Saxtfragion continentalis)

Molecular Characteristics of Extraintestinal Pathogenic E. coli (ExPEC), Uropathogenic E. coli (UPEC), and Multidrug Resistant E. coli Isolated from Healthy Dogs in Spain. Whole Genome Sequencing of Canine ST372 Isolates and Comparison with Human Isolates Causing Extraintestinal Infections

Under a one health perspective and the worldwide antimicrobial resistance concern, we investigated extraintestinal pathogenic Escherichia coli (ExPEC), uropathogenic E. coli (UPEC), and multidrug resistant (MDR) E. coli from 197 isolates recovered from healthy dogs in Spain between 2013 and 2017. A total of 91 (46.2%) isolates were molecularly classified as ExPEC and/or UPEC, including 50 clones, among which (i) four clones were dominant (B2-CH14-180-ST127, B2-CH52-14-ST141, B2-CH103-9-ST372 and F-CH4-58-ST648) and (ii) 15 had been identified among isolates causing extraintestinal infections in Spanish and French humans in 2015 and 2016. A total of 28 (14.2%) isolates were classified as MDR, associated with B1, D, and E phylogroups, and included 24 clones, of which eight had also been identified among the human clinical isolates. We selected 23 ST372 strains, 21 from healthy dogs, and two from human clinical isolates for whole genome sequencing and built an SNP-tree with these 23 genomes and 174 genomes (128 from canine strains and 46 from human strains) obtained from public databases. These 197 genomes were segregated into six clusters. Cluster 1 comprised 74.6% of the strain genomes, mostly composed of canine strain genomes (p < 0.00001). Clusters 4 and 6 also included canine strain genomes, while clusters 2, 3, and 5 were significantly associated with human strain genomes. Finding several common clones and clone-related serotypes in dogs and humans suggests a potentially bidirectional clone transfer that argues for the one health perspective

Circundatin H, a new inhibitor of mitochondrial NADH oxidase from Aspergillus ochraceus

[EN] Circumdatin H (1), a new alkaloid from the culture broth of Aspergillus ochraceus, has been isolated, together with a known circumdatin, circumdatin E (2) and other known compounds: flavacol (3) and stephacidin A (4). The structure of 1 was established on the basis of chemical and spectral evidence. All of these alkaloids showed biological activity as inhibitors of the mammalian mitochondrial respiratory chain.López-Gresa, MP.; Gonzalez Más, MC.; Primo, J.; Moya, P.; Romero, V.; Estornell, E. (2005). Circundatin H, a new inhibitor of mitochondrial NADH oxidase from Aspergillus ochraceus. The Journal of Antibiotics. 58:416-419. http://hdl.handle.net/10251/134335S4164195