2,457 research outputs found
Exact Histogram Specification Optimized for Structural Similarity
An exact histogram specification (EHS) method modifies its input image to
have a specified histogram. Applications of EHS include image (contrast)
enhancement (e.g., by histogram equalization) and histogram watermarking.
Performing EHS on an image, however, reduces its visual quality. Starting from
the output of a generic EHS method, we maximize the structural similarity index
(SSIM) between the original image (before EHS) and the result of EHS
iteratively. Essential in this process is the computationally simple and
accurate formula we derive for SSIM gradient. As it is based on gradient
ascent, the proposed EHS always converges. Experimental results confirm that
while obtaining the histogram exactly as specified, the proposed method
invariably outperforms the existing methods in terms of visual quality of the
result. The computational complexity of the proposed method is shown to be of
the same order as that of the existing methods.
Index terms: histogram modification, histogram equalization, optimization for
perceptual visual quality, structural similarity gradient ascent, histogram
watermarking, contrast enhancement
Magnetic and superconducting instabilities of the Hubbard model at the van Hove filling
We use a novel temperature-flow renormalization group technique to analyze
magnetic and superconducting instabilities in the two-dimensional t-t' Hubbard
model for particle densities close to the van Hove filling as a function of the
next-nearest neighbor hopping t'. In the one-loop flow at the van Hove filling,
the characteristic temperature for the flow to strong coupling is suppressed
drastically around t'_c approx. -0.33t, suggesting a quantum critical point
between d-wave pairing at moderate t'>t'_c and ferromagnetism for t'<t'_c. Upon
increasing the particle density in the latter regime the leading instability
occurs in the triplet pairing channel.Comment: 4 pages, to appear in Physical Review Letter
Observations of the Hubble Deep Field with the Infrared Space Observatory. I. Data reduction, maps and sky coverage
We present deep imaging at 6.7 micron and 15 micron from the CAM instrument
on the Infrared Space Observatory (ISO), centred on the Hubble Deep Field
(HDF). These are the deepest integrations published to date at these
wavelengths in any region of sky. We discuss the observation strategy and the
data reduction. The observed source density appears to approach the CAM
confusion limit at 15 micron, and fluctuations in the 6.7 micron sky background
may be identifiable with similar spatial fluctuations in the HDF galaxy counts.
ISO appears to be detecting comparable field galaxy populations to the HDF, and
our data yields strong evidence that future IR missions (such as SIRTF, FIRST
and WIRE) as well as SCUBA and millimetre arrays will easily detect field
galaxies out to comparably high redshifts.Comment: 7 pages, LaTeX (using mn.sty), 9 figures included as GIFs. Gzipped
Postscipt version available from http://artemis.ph.ic.ac.uk/hdf/papers/ps/.
Further information on ISO-HDF project can be found at
http://artemis.ph.ic.ac.uk/hdf
NeuroD1 regulation of migration accompanies the differential sensitivity of neuroendocrine carcinomas to TrkB inhibition
The developmental transcription factor NeuroD1 is anomalously expressed in a subset of aggressive neuroendocrine tumors. Previously, we demonstrated that TrkB and neural cell adhesion molecule (NCAM) are downstream targets of NeuroD1 that contribute to the actions of neurogenic differentiation 1 (NeuroD1) in neuroendocrine lung. We found that several malignant melanoma and prostate cell lines express NeuroD1 and TrkB. Inhibition of TrkB activity decreased invasion in several neuroendocrine pigmented melanoma but not in prostate cell lines. We also found that loss of the tumor suppressor p53 increased NeuroD1 expression in normal human bronchial epithelial cells and cancer cells with neuroendocrine features. Although we found that a major mechanism of action of NeuroD1 is by the regulation of TrkB, effective targeting of TrkB to inhibit invasion may depend on the cell of origin. These findings suggest that NeuroD1 is a lineage-dependent oncogene acting through its downstream target, TrkB, across multiple cancer types, which may provide new insights into the pathogenesis of neuroendocrine cancers
Infrared Constraints on AGN Tori Models
This work focuses on the properties of dusty tori in active galactic nuclei
(AGN) derived from the comparison of SDSS type 1 quasars with mid-Infrared
(MIR) counterparts and a new, detailed torus model. The infrared data were
taken by the Spitzer Wide-area InfraRed Extragalactic (SWIRE) Survey. Basic
model parameters are constraint, such as the density law of the graphite and
silicate grains, the torus size and its opening angle. A whole variety of
optical depths is supported. The favoured models are those with decreasing
density with distance from the centre, while there is no clear tendency as to
the covering factor, ie small, medium and large covering factors are almost
equally distributed. Based on the models that better describe the observed
SEDs, properties such as the accretion luminosity, the mass of dust, the inner
to outer radius ratio and the hydrogen column density are computed.Comment: 4 pages, 4 figures, to appear in "Infrared Diagnostics of Galaxy
Evolution", ASP Conference Series, Pasadena, 14-16 November 200
Unveiling the Active Nucleus of Centaurus A
We report new HST WFPC2 and NICMOS observations of the center of the nearest
radio galaxy Centaurus A (NGC 5128) and discuss their implications for our
understanding of the active nucleus and jet. We detect the active nucleus in
the near-IR (K and H) and, for the first time, in the optical (I and V),
deriving the spectral energy distribution of the nucleus from the radio to
X-rays. The optical and part of the near-IR emission can be explained by the
extrapolation of the X-ray power law reddened by A_V~14mag, a value consistent
with other independent estimates.
The 20pc-scale nuclear disk discovered by Schreier et al. (1998) is detected
in the [FeII] 1.64mic line and presents a morphology similar to that observed
in Pa alpha with a [FeII]/Pa alpha ratio typical of low ionization Seyfert
galaxies and LINERs. NICMOS 3 Pa alpha observations in a 50"x50" circumnuclear
region suggest enhanced star formation (~0.3Msun/yr) at the edges of the
putative bar seen with ISO, perhaps due to shocks driven into the gas.
The light profile, reconstructed from V, H and K observations, shows that
Centaurus A has a core profile with a resolved break at ~4" and suggests a
black--hole mass of ~10^9 Msun. A linear blue structure aligned with the
radio/X-ray jet may indicate a channel of relatively low reddening in which
dust has been swept away by the jet.Comment: 19 pages, 13 figures, Astrophysical Journal, in press. High quality
figures available at http://www.arcetri.astro.it/~marconi/colpic.htm
Serum levels and removal by haemodialysis and haemodiafiltration of tryptophan-derived uremic toxins in ESKD patients
Tryptophan is an essential dietary amino acid that originates uremic toxins that contribute to end-stage kidney disease (ESKD) patient outcomes. We evaluated serum levels and removal during haemodialysis and haemodiafiltration of tryptophan and tryptophan-derived uremic toxins, indoxyl sulfate (IS) and indole acetic acid (IAA), in ESKD patients in different dialysis treatment settings. This prospective multicentre study in four European dialysis centres enrolled 78 patients with ESKD. Blood and spent dialysate samples obtained during dialysis were analysed with high-performance liquid chromatography to assess uremic solutes, their reduction ratio (RR) and total removed solute (TRS). Mean free serum tryptophan and IS concentrations increased, and concentration of IAA decreased over pre-dialysis levels (67%, 49%, -0.8%, respectively) during the first hour of dialysis. While mean serum total urea, IS and IAA concentrations decreased during dialysis (-72%, -39%, -43%, respectively), serum tryptophan levels increased, resulting in negative RR (-8%) towards the end of the dialysis session (p < 0.001), despite remarkable Trp losses in dialysate. RR and TRS values based on serum (total, free) and dialysate solute concentrations were lower for conventional low-flux dialysis (p < 0.001). High-efficiency haemodiafiltration resulted in 80% higher Trp losses than conventional low-flux dialysis, despite similar neutral Trp RR values. In conclusion, serum Trp concentrations and RR behave differently from uremic solutes IS, IAA and urea and Trp RR did not reflect dialysis Trp losses. Conventional low-flux dialysis may not adequately clear Trp-related uremic toxins while high efficiency haemodiafiltration increased Trp losses
The temperature-flow renormalization group and the competition between superconductivity and ferromagnetism
We derive a differential equation for the one-particle-irreducible vertex
functions of interacting fermions as a function of the temperature. Formally,
these equations correspond to a Wilsonian renormalization group scheme which
uses the temperature as an explicit scale parameter. Our novel method allows us
to analyze the competition between superconducting and various magnetic Fermi
surface instabilities in the one-loop approximation. In particular this
includes ferromagnetic fluctuations, which are difficult to treat on an equal
footing in conventional Wilsonian momentum space techniques. Applying the
scheme to the two-dimensional t-t' Hubbard model we investigate the RG flow of
the interactions at the van Hove filling with varying next-nearest neighbor
hopping t'. Starting at t'=0 we describe the evolution of the flow to strong
coupling from an antiferromagnetic nesting regime over a d-wave regime at
moderate t' to a ferromagnetic region at larger absolute values of t'. Upon
increasing the particle density in the latter regime the ferromagnetic
tendencies are cut off and the leading instability occurs in the triplet
superconducting pairing channel.Comment: 18 pages, 11 figure
Observations of the Hubble Deep Field with the Infrared Space Observatory V. Spectral energy distributions starburst models and star formation history
We have modelled the spectral energy distributions of the 13 Hubble Deep Field (HDF) galaxies reliably detected by the Infrared Space Observatoiy (ISO). For two galaxies the emission detected by ISO is consistent with being starlight or the infrared 'cirrus' in the galaxies. For the remaining 11 galaxies there is a clear mid-infrared excess, which we interpret as emission from dust associated with a strong starburst. 10 of these galaxies are spirals or interacting pairs, while the remaining one is an elliptical with a prominent nucleus and broad emission lines. We give a new discussion of how the star formation rate can be deduced from the far-infrared luminosity, and derive star formation rates for these galaxies of 8-1000ø M¿ yr-1, where ø takes account of the uncertainty in the initial mass function. The HDF galaxies detected by ISO are clearly forming stars at a prodigious rate compared with nearby normal galaxies. We discuss the implications of our detections for the history of star and heavy element formation in the Universe. Although uncertainties in the calibration, reliability of source detection, associations and starburst models remain, it is clear that dust plays an important role in star formation out to redshift 1 at least
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