523 research outputs found

    A digital audience study for a museum and a confined society

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    [EN] 2020 has been, for obvious reasons, a complicated year for society and within it for museums and their visitors. Being physically closed (and later limited in terms of access and accessibility) meant that we had to be more open than ever digitally. At the National Museum of Anthropology we carry out a specific plan to address this year's special situation of Covid. At the end of the year, it was necessary to analyze how the new digital strategies had worked and how they were related to the "physical" activity of the museum. For this reason, we decided to carry out a study of the digital audience, taking advantage of the fact that the year offered very different time ranges. We analyze the data offered by our website (through google analytics) and by our social networks and we cross them with each moment of the year and the physical activity of the museum. In the communication we will explain the methodology and expand the general conclusions drawn from the study about the digital public.[ES] El 2020 ha sido, por razones obvias, un año complicado para la sociedad y dentro de ella para los museos y sus visitantes. Estar cerrados físicamente (y posteriormente limitados en cuanto a acceso y accesibilidad) provocó que tuviésemos que estar más abiertos que nunca de forma digital. En el Museo Nacional de Antropología llevamos a cabo un plan específico para abordar la especial situación de este año del Covid. Al terminar el año, era necesario analizar como habían funcionado las nuevas estrategias digitales y que relación tenían con la actividad "física" del museo. Por ello decidimos llevar a cabo un estudio de público digital aprovechando que el año ofrecía horquillas temporales muy diferenciadas. Analizamos los datos ofrecidos por nuestra página web (a través de google analitycs) y por nuestras redes sociales y los cruzamos con cada momento del año y la actividad física del museo. En la comunicación explicaremos metodología y ampliaremos las conclusiones generales que del estudio se extrae sobre el público digital.Sánchez Gómez, P.; González, ÁJ. (2022). Un estudio de público digital para un museo y una sociedad confinada. En CIMED21 - I Congreso internacional de museos y estrategias digitales. Editorial Universitat Politècnica de València. 629-649. https://doi.org/10.4995/CIMED21.2021.12215OCS62964

    Arqueología pública y género: estrategias para nuevas formas de relación con la sociedad

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    Despite the undeniable social implications of its practice and the possibilities of intervention it has, Public Archaeology has not made a conscious reflection that includes issues related to gender and the relationships between women and men. This implies two consequences, on the one hand, in many of the discourses that are transferred to society, there are still stereotypes that have not been analysed critically, but on the other it is precisely in some strategies of Public Archaeology that the researchers interested in the women’s studies and gender are finding a way to transmit new concepts that do not always find a place in more traditional formats. In this article, we will review some of those practices that put women at the forefront to assess their relevance and their effect on society

    MIRACLE’s hybrid approach to bilingual and monolingual Information Retrieval

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    The main goal of the bilingual and monolingual participation of the MIRACLE team at CLEF 2004 was testing the effect of combination approaches to information retrieval. The starting point is a set of basic components: stemming, transformation, filtering, generation of n-grams, weighting and relevance feedback. Some of these basic components are used in different combinations and order of application for document indexing and for query processing. Besides this, a second order combination is done, mainly by averaging or by selective combination of the documents retrieved by different approaches for a particular query

    A transcriptomic approach highlights induction of secondary metabolism in citrus fruit in response to Penicillium digitatum infection

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    <p>Abstract</p> <p>Background</p> <p>Postharvest losses of citrus fruit due to green mold decay, caused by the fungus <it>Penicillium digitaum</it>, have a considerable economic impact. However, little is known about the molecular processes underlying the response of citrus fruit to <it>P. digitatum</it>.</p> <p>Results</p> <p>Here we describe the construction of a subtracted cDNA library enriched in citrus genes preferentially expressed in response to pathogen infection followed by cDNA macroarray hybridization to investigate gene expression during the early stages of colonization of the fruit's peel by <it>P. digitatum</it>. Sequence annotation of clones from the subtracted cDNA library revealed that induction of secondary and amino acid metabolisms constitutes the major response of citrus fruits to <it>P. digitatum </it>infection. Macroarray hybridization analysis was conducted with RNA from either control, wounded, ethylene treated or <it>P. digitatum </it>infected fruit. Results indicate an extensive overlap in the response triggered by the three treatments, but also demonstrated specific patterns of gene expression in response to each stimulus. Collectively our data indicate a significant presence of isoprenoid, alkaloid and phenylpropanoid biosynthetic genes in the transcriptomic response of citrus fruits to <it>P. digitatum </it>infection. About half of the genes that are up-regulated in response to pathogen infection are also induced by ethylene, but many examples of ethylene-independent gene regulation were also found. Two notable examples of this regulation pattern are the genes showing homology to a caffeine synthase and a berberine bridge enzyme, two proteins involved in alkaloid biosynthesis, which are among the most induced genes upon <it>P. digitatum </it>infection but are not responsive to ethylene.</p> <p>Conclusions</p> <p>This study provided the first global picture of the gene expression changes in citrus fruit in response to <it>P. digitatum </it>infection, emphasizing differences and commonalities with those triggered by wounding or exogenous ethylene treatment. Interpretation of the differentially expressed genes revealed that metabolism is redirected to the synthesis of isoprenes, alkaloids and phenylpropanoids.</p

    An in vitro evaluation of two dentine adhesive systems to seal the pulp chamber using a glucose penetration model

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    Objectives: To evaluate the sealing capability of Cavit TM G with or without Clearfil TM S3 Bond and Prime & Bond NT placed in the pulp chamber. Study Design: Forty single rooted premolars, extracted for orthodontic and periodontal reasons, with intact coronal surface and mature apices, were standardized to a length of 15 mm. The teeth were instrumented, filled with a gutta-percha master cone and divided into three groups to obturate the pulp chambers: Cavit TM G; Clearfil TM S3 Bond plus Cavit TM G and Prime & Bond® NT plus Cavit TM G. A glucose leakage model was used for evaluating the coronal microleakage. The Mann-Whitney test was used to evaluate the differences in the means of the glucose leakage. Results: An increase in glucose penetration was observed during the first week in groups Cavit TM G and Cavit TM G+PBNT. The glucose penetration values of all groups were similar at 30 and 45 days, and there were no significant differences among them in both time periods (p=0.736 and p=0.581, respectively). Conclusions: The adhesive systems did not improve the capability of Cavit TM G to seal the pulp chamber over time © Medicina Oral S. L

    Empleo de Trefoil Factor-Family 3 (TFF3) en el pronóstico de pacientes diagnosticados con cáncer colorrectal

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    Peer reviewedUniversidad Autónoma de Madrid, Fundación para la Investigación Biomédica del Hospital Universitario de la Paz, Consejo Superior de Investigaciones CientíficasT3 Traducción de patente europe

    Intraorifice sealing ability of different materials in endodontically treated teeth

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    Objectives: To evaluate Cavit? G, ProRoot? MTA and Tetric® EvoFlow as intraorifice barriers to prevent coronal microleakage in root canal treatment. Study Design: Forty-two human single rooted teeth were divided randomly in three experimental groups of 10 specimens each and two control groups. The experimental groups were prepared with hand instrumentation and cold lateral condensed technique of the gutta-percha. Four millimetres of coronal gutta-percha were removed and replaced by one of the following filling materials: Cavit? G, Tetric® EvoFlow or ProRoot? MTA. In the experimental groups, leakage was measured by the concentration of leaked glucose in the apical reservoir at 1, 7, 30, and 45 days, using the enzymatic glucose oxidase method. Data were analyzed by means of Mann-Whitney U and Kruskal-Wallis tests at ?=0.05. Results: The glucose penetration results of three experimental groups increased gradually over time. No significant differences were found among groups at 24 hours and 1 week. At thirty and forty-five days, Cavit? and Tetric® EvoFlow values were significantly different (p=0.007 and p=0.023, respectively). Conclusions: The sealing ability of the Cavit? G, ProRoot? MTA and Tetric® EvoFlow used as intraorifice materials tends to be similar over time

    Oral mite anaphylaxis by Thyreophagus entomophagus in a child: a case report

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    Sensitization to Thyreophagus entomophagus, a storage mite, is uncommon and might produce occupational respiratory disorders in farmers. We present the first case of a child suffering anaphylaxis produced by ingestion of contaminated flour with Thyreophagus entomophagus

    miraQA: Initial experiments in Question Answering

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    We present the miraQA system that constitutes MIRACLE first experience in Question Answering for monolingual Spanish and has been developed for QA@CLEF 2004. The architecture of the system is described and details of our approach to Statistical Answer Extraction based on Hidden Markov Models are presented. One run that uses last year question set for training purposes has been submitted. The results are presented together with ideas for improvement

    Biodetection Techniques for Quantification of Chemokines

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    Chemokines are a class of cytokine whose special properties, together with their involvement and relevant role in various diseases, make them a restricted group of biomarkers suitable for diagnosis and monitoring. Despite their importance, biodetection techniques dedicated to the selective determination of one or more chemokines are very scarce. For some years now, the critical diagnosis of inflammatory diseases by detecting both cytokine and chemokine biomarkers, has had a strong impact on the development of multiple detection platforms. However, it would be desirable to implement methodologies with a higher degree of selectivity for chemokines, in order to provide more precise information. In addition, better development of biosensor technology applied to this specific field would make it possible to address the main challenges of detection methods for several diseases with a high incidence in the population, avoiding high costs and low sensitivity. Taking this into account, this review aims to present the state of the art of chemokine biodetection techniques and emphasize the role of these systems in the prevention, monitoring and treatment of various diseases associated with chemokines as a starting point for future developments that are also analyzed throughout the article.Depto. de Química AnalíticaFac. de Ciencias QuímicasTRUEMinisterio de Ciencia, Innovación y UniversidadesComunidad de Madridpu
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