20 research outputs found

    Analysis of the Health Prevention study program in the Medicine career

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    Introducción: el continuo perfeccionamiento en el sector salud, sustentado en un nuevo modelo económico, traza dentro de sus objetivos: el fortalecimiento de las estrategias de formación, capacitación e investigación. Como resultado de este proceso hubo un perfeccionamiento en la carrera de Medicina y, con ello, en la asignatura.Objetivo: evaluar el programa de la asignatura Prevención en Salud, a partir de lo regulado en el reglamento vigente para el trabajo docente-metodológico.Métodos: se realizó un análisis crítico, valorativo y reflexivo, que conllevó a una revisión exhaustiva del contenido, del basamento legal que norma el trabajo docente-metodológico para la enseñanza superior, así como artículos originales y de revisión relacionados con la temática. También se analizaron las orientaciones metodológicas para los cursos académicos 2017-2018, 2018-2019 y 2019-2020, y el tipo de profesional que demanda la sociedad.  Resultados: se redujeron 16 horas en el tema III y se incrementaron al tema II, de manera que permitiera al estudiante trabajar no solo lo relacionado con familia y comunicación, sino también profundizar en la identificación de los problemas de salud de las familias, e integrar el conocimiento de algunos de los programas priorizados abordados en el tema I, así como en los contenidos de las asignaturas precedentes.Conclusiones: las deficiencias detectadas en el programa de la asignatura Prevención en Salud, como resultado del análisis crítico, valorativo y reflexivo, encontraron respuestas en las propuestas de cambio que realizaron los autores.Introduction: the continuous improvement in the health sector, supported by a new economic model, outlines within its objectives: the strengthening of education, training and research strategies. As a result of this process, there was an improvement in the Medicine degree and, with it, in the subject.Objective: evaluate the program of the Health Prevention subject, based on what is regulated in the current regulations for teaching-methodological work.Methods: a critical, evaluative and reflective analysis was carried out, which led to an exhaustive review of the content, the legal basis that regulates the teaching-methodological work for higher education, as well as original and review articles related to the topic. The methodological guidelines for the 2017-2018, 2018-2019 and 2019-2020 academic years were also analyzed, and the type of professional that society demands.Results: 16 hours were reduced in topic III and increased to topic II, in a way that allowed the student to work not only on what is related to family and communication, but also to deepen the identification of family health problems, and integrate knowledge of some of the prioritized programs addressed in topic I, as well as the contents of the preceding subjects.Conclusions: the deficiencies detected in the program of the subject Prevention in Health, as a result of the critical, evaluative and reflective analysis, found answers in the proposals for change made by the authors

    Comunidades de coralígeno ligadas a procesos diapíricos de la plataforma española del golfo de Cádiz

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    The Gulf of Cádiz (GoC) represents an important area of seepage activity and of biological diversity due to the tectonic activity and subsoil fluid mobility, as well as the confluence of Atlantic and Mediterranean water masses and organisms from both basins. Some circalittoral and bathyal areas of the GoC remain still unexplored and they could harbour interesting communities and species that may deserve protection. In summer 2013, a geological expedition carried out between San Fernando and Conil de la Frontera, at water depths between 40 and 55 m and 10 M from Cádiz detected complex coralligenous communities that may be linked to diapiric processes. These communities represent a well preserved 1170 habitat type (Reefs) of the Habitat Directive and also contain ca. 20 spp. of invertebrates that are included in European, National and Local (Andalusian) threatened species lists. The area should be included in the Natura 2000 network as it represents one of the few circalittoral coralligenous communities from Spanish waters of the GoC.Versión del edito

    Maintenance therapy with bortezomib plus thalidomide or bortezomib plus prednisone in elderly multiple myeloma patients included in the GEM2005MAS65 trial

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    [EN]Maintenance therapy has become a hot field in myeloma, and it may be particularly relevant in elderly patients because the major benefit results from the initial therapy. We report the results of a randomized comparison of maintenance with bortezomib plus thalidomide (VT) or prednisone (VP) in 178 elderly untreated myeloma patients who had received 6 induction cycles with bortezomib plus either melphalan and prednisone or thalidomide and prednisone. The complete response (CR) rate increased from 24% after induction up to 42%, higher for VT versus VP (46% vs 39%). Median progression-free survival (PFS) was superior for VT (39 months) compared with VP (32 months) and overall survival (OS) was also longer in VT patients compared with VP (5-year OS of 69% and 50%, respectively) but the differences did not reach statistical significance. CR achievement was associated with a significantly longer PFS (P < .001) and 5-year OS (P < .001). The incidence of G3-4 peripheral neuropathy was 9% for VT and 3% for VP. Unfortunately, this approach was not able to overcome the adverse prognosis of cytogenetic abnormalities. In summary, these maintenance regimens result in a significant increase in CR rate, remarkably long PFS, and acceptable toxicity profile. The trial is registered at www.clinicaltrials.gov as NCT00443235

    Cultura, innovación, internacionalización y vinculación de la Pyme con la Universidad : barómetro económico de la PYME 2011

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    Este barómetro corresponde al año 2011 y recoge información sobre: •Características generales de la empresa y expectativas. •Grado y capacidad de internacionalización de la empresa. •Relación de la empresa con el medio-ambiente. •Tecnología y grado de innovación de la empresa. •Organización, cultura empresarial y estrategia. •Vinculación de la empresa con la Universidad. •Evolución del rendimiento de la empresa respecto de la competenciaRegión de Murcia, Consejería de Universidades, Empresas e Innovación, INFO (Instituto de Fomento de la Regiñon de Murcia

    Compact modeling of the effects of illumination on the contact region of organic phototransistors

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    Please cite this article as: A. Romero, C. Jiménez, J. González, P. López-Varo, M.J. Deen, J.A. Jiménez-Tejada, Compact modeling of the effects of illumination on the contact region of organic phototransistors, Organic Electronics, (2019), 70, 113-121.A good modeling of degrading effects in an electronic device, such as the contact region of organic phototransistors (OPTs), can be favorably used to better describe and optimize the performance of the whole device. Furthermore, a proper design of the contacts can enhance the exciton dissociation and the extraction of photogenerated charge in the device. In this work, a compact model for OPTs is developed. This model is valid for all the operation regimes of the transistors. It includes a model for the contact region of the device that incorporates the effects of illumination. The compact model and the contact region model are validated with published experimental data from several OPTs under different illumination conditions. The tool used to validate the model is an evolutionary parameter extraction procedure developed in a previous work. The results show that both photoconductive and photovoltaic effects impact the intrinsic region of the transistor, as well as the electrical behavior of the contact region. The parameters used in the contact region model are linked to these photovoltaic and photoconductive effects.This work was supported by projects MAT2016-76892-C3-3-R and TIN2015-67020-P funded by the Spanish Government and European Regional Development Funds (ERDF) and by “Beca de Iniciación a la Investigación para estudiantes de Grado” given by the University of Granada

    Evidence supporting the value of spontaneous vegetation for phytomanagement of soil ecosystem functions in abandoned metal(loid) mine tailings

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    This work studies a set of soil indicators (physical, physico-chemical and biological), evaluated under field and laboratory conditions, in different stages of spontaneous vegetation colonization in abandoned metal(loid) mine tailings from Mediterranean semiarid areas. The results provide evidence about the interest of spontaneous colonization by native vegetation for the phytomanagement of abandoned metal(loid) mine tailings in terms of providing ecosystem functions. Bare soils (B), small groups of pine trees (P), scattered pine trees with shrubs and herbs under the canopy (P+S), and dense patches of pine trees with shrubs and herbs under the canopy (DP+S) were studied inside mine tailings abandoned ≈40 years ago. Besides, pine forests next (FN) and away (FA) from the tailings were also studied. Pioneer and nurse plants were mainly found inside the tailings, although ecological indexes in P+S and DP+S were similar to FN and FA. Pedogenesis evidences such as structure development and increase in cation exchange capacity, organic C and N were found in tailing soils from B to DP+S. However, soil metal(loid)s did not follow the same variation pattern. For example (in mg kg-1): P showed the maximum total Cu (≈277) and Zn (≈17,860), while P+S of As (≈1250) and Pb (≈14,570). B had the maximum water extractable Pb (≈4) and Zn (≈207), while FA of As (≈0.192) and Cu (≈0.149). Soil microbial biomass C, enzyme activity, CO2 emission, organic matter decomposition and feeding activity of soil dwelling organisms indicated similar, or even higher, biological activity in P+S and DP+S than in FN and FA. In fact, FA showed the highest soil ecotoxicity risk (reduced enchytraeid reproduction). Therefore, mine tailing soils can be effectively modified following spontaneous vegetation colonization, achieving conditions with capacity to provide certain ecosystem functions. Hence, phytomanagement of these tailings should be preceded by a detailed knowledge of the existing spontaneously colonized sites, which should be preserved to take advantage of their potentiality.Support for this research was provided by the Ministry of Science, Innovation and Universities of Spain through FEDER funds (RESCLICONT project - CGL2016-80981-R). A. Peñalver-Alcalá was hired by this project and received a grant from the Technical University of Cartagena for a short stay at the University of Aveiro. We much appreciate the help of Héctor M. Conesa and Irene Sánchez during field and laboratory work. We thank to the technicians of the SAIT-UPCT for their laboratory and analytical assessments. This work is dedicated to memory of our friend and master, Professor Dr. Mariano Simón Torres, one of the best ever Spanish pedologist, who sadly passed away in April 2019
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