166 research outputs found
Morpho-syntactic variations in English and Spanish clipped words: a contrastive study
Clipping and linguistic variation are inexorably interconnected. Shortened or elliptical words reflect a great deal of variability of the language, especially in the morphological and phonological levels. The object of this study is precisely to explore the phono-graphemic and grammatical variations occurred in the visible changes undergone by clipped words in Spanish and English. A contrastive analysis of this type reveals both expectedly different correspondences in terms of gender and number, and surprisingly parallel lexico-syntactic features. This suggests that clipped or elliptical units are not only necessarily dependent on intrinsic morpho-grammatical and phonological traits, but they are also characterized by regularities and universal patterns that might show disruptive or “corrupted” constructs. This analysis confirms the peculiarities of clipping and linguistic variations in both languages, in an attempt to comprehend the interconnection between functional motivations, and morphological and phonological changes
Endovascular treatment of thoracic aorta injury after spinal column surgery
Producción CientíficaA 61-year-old woman with a history of left dorso-lumbar scoliosis and
severe dorso-lumbar kyphosis underwent surgical treatment of a spinal deformity.
Surgery was conducted on the patient by performing a dorso-lumbar spinal
arthrodesis (T6-L5) by means of the insertion of two longitudinal rods and a
number of pedicle-expander screws at different vertebral levels.
Following the orthopedic surgery, the patient presented paraparesis of the lower
limbs and anemia that required transfusion.
In the immediate postoperative period, a noncontrast-enhanced computed
tomography (CT) scan was obtained to assess the medullary canal. A deviation of
the left screw placed at T6 was detected; this screw projected outward from the
vertebral cortex, protruding into the descending thoracic aorta.
A contrast-enhanced CT scan showed that the screw had been malpositioned,
and the image was highly suggestive of a perforation of the aortic wall, despite a
lack of evidence of a peri-aortic hematoma, extravasation of contrast medium,
or pleural effusion. The patient remained hemodynamically stable, and the
decision was to perform an endovascular repair electively within 24 hours
Influence of aspirin therapy in the ulcer associated with chronic venous insufficiency
Producción CientíficaBackground: To determine the effect of aspirin on ulcer healing rate in patients with chronic
venous insufficiency, and to establish prognostic factors that influence ulcer evolution.
Methods: Between 2001 and 2005, 78 patients with ulcerated lesions of diameter >2 cm and
associated with chronic venous insufficiency were evaluated in our hospital. Of these, 51 patients
(22 men, 29 women) with mean age of 60 years (range: 36e86) were included in a prospective
randomized trial with a parallel control group. The treatment group received 300 mg of aspirin and
the control group received no drug treatment; in both groups, healing was associated with standard
compression therapy. During follow-up, held weekly in a blinded fashion, there was ulcer
healing as well as cases of recurrence. Results were analyzed by intention-to-treat approach.
Cure rate was estimated using KaplaneMeir survival analysis, and the influence of prognostic
factors was analyzed by applying the Cox proportional hazards model.
Results: In the presence of gradual compression therapy, healing occurred more rapidly in
patients receiving aspirin versus the control subjects (12 weeks in the treated group vs. 22
weeks in the control group), with a 46% reduction in healing time. The main prognostic factor
was estimated initial area of injury (P ¼ 0.032). Age, sex, systemic therapy, and infection
showed little relevance to evolution.
Conclusions: The administration of aspirin daily dose of 300 mg shortens the healing time of
ulcerated lesions in the chronic venous insufficiency (CVI). The main prognostic factor for healing
of venous ulcerated lesions is the initial surface area of the ulcer
El tratamiento lexicográfico de las palabras truncadas en español e italiano
Este artículo tiene como objetivo estudiar el contenido lexicográfico de dos diccionarios descriptivos en español y en italiano: Diccionario del español actual (DEA) y Lo Zingarelli 2019 Vocabolario della lingua italiana (Z) en lo que se refiere al concepto de truncamiento léxico. La recopilación de lemas truncados de los diccionarios en los dos idiomas permitirá mostrar características convergentes y divergentes de los diccionarios descriptivos, en particular las marcas léxicas y sociolingüísticas.This article is intended to examine the lexicographic repertoires of two descriptive dictionaries in Spanish and Italian: Diccionario del español actual (DEA) and Lo Zingarelli 2019 Vocabolario della lingua italiana (Z), as regards the definition of clipped words. The compilation of clipped lemmas in both languages can shed more light on similar and divergent features of these dictionaries, particularly on lexical and sociolinguistic markedness
Effect of anticoagulant therapy in tehe incidence of post-throbotic syndrome and recurrent thromboemboembolism : comparative study of euoxeparin versus coumarin
Producción CientíficaObjective: We evaluated the effect of long-term anticoagulant treatment (enoxaparin vs coumarin) in patients with deep
venous thrombosis (DVT) as to incidence of post-thrombotic syndrome (PTS) and recurrent venous thromboembolism.
We also analyzed the impact of thrombus regression after the anticoagulant treatment for these two outcomes.
Methods: A prospective study was designed in which 165 patients with symptomatic, unilateral, first-episode DVT were
randomized to a long-term anticoagulant treatment with coumarin or enoxaparin during at least 3 months. The rate of
thrombus regression was defined as the difference in Marder score after 3 months of treatment by venography. Follow-up
was performed at 3, 6, and 12 months, and yearly thereafter for 5 years. Venous disease was related to pathologic severity
of PTS according to the validated scale of Villalta as rated by a physician blinded to treatment. Recurrence of symptomatic
venous thromboembolism was documented objectively.
Results: The 5-year follow-up period was completed for 100 patients (enoxaparin, 56; coumarin, 44). A lesser incidence
of PTS was observed in the enoxaparin group (39.3% absent, 19.6% severe) than in the coumarin group (29.5% absent,
29.5% severe), although this difference was not statistically significant. The accumulated recurrence rate was 19.3% with
enoxaparin compared with 36.6% with coumarin (P .02). Although the mean Marder score was significantly improved
in both groups (49.1% for enoxaparin vs 24.0% for coumarin; P .016), a lower reduction in thrombus size was
associated with higher clinical events of recurrence (hazard ratio 1.97; 95% CI, 1.06-3.66; P .032). A significant
inverse correlation was also found between the degree of thrombus regression at 3 months and the incidence at 5 years
of PTS (P .007).
Conclusions: Residual venous thrombosis is an important risk factor for recurrent thromboembolism and PTS. A greater
reduction in thrombus size was associated with lesser clinical events of recurrence and consequently a lesser rate of PTS.
However, despite a greater recanalization with enoxaparin, the incidence of PTS was similar between both treatment
groups, probably because of the small sample size. Further investigations are needed to clarify the implication of the
anticoagulant treatment in the severity of PTS. (J Vasc Surg 2008;48:953-9.
Mortality in patients undergoing open aortoiliac surgery : prognostic value of troponin T in tehe inmediate postoperative period
Producción CientíficaBackground: Patients undergoing open aortoiliac surgery constitute a high-risk subgroup. The
aim of this study was to evaluate the relationship between postoperative troponin T (TnT) elevation
with the associated postoperative mortality, and mean hospital stay.
Methods: This was a prospective observational study of consecutive patients who underwent
open aortoiliac surgery during 2006. TnT levels in the first 72 hours after the operation, immediate
mortality, postoperative care unit stay, and total postoperative hospital stay were recorded.
Statistical analyses were performed with the program SPSS 14.0; the chi-square test (or the
Fisher’s exact test) was used for qualitative variables and the ManneWhitney test for quantitative
variables.
Results: Of the 65 patients included in the study, postoperative TnT was elevated in 14 (21.5%)
patients. No significant differences were found in age, sex, hypertension, dyslipidemia, smoking,
diabetes mellitus, ischemic heart disease, heart failure, bronchopathy, or renal failure between
groups. Mortality in patients with elevated TnT levels was significantly higher (42% compared
with 3.92%; relative risk 10.93 ± 0.76; p ¼ 0.001). Likewise, their mean postoperative intensive
care unit stay was significantly greater (23.21 ± 6.96 days compared to 2.86 ± 1.96; p < 0.001).
This finding resulted in a significantly longer postoperative hospital stay (32.57 ± 25.38 days
compared with 12.47 ± 2.21).
Conclusion: TnT level in the immediate postoperative period is a highly relevant indicator of
prognosis in patients undergoing major vascular surger
Shotgun wound and pellet embolism to the intracranial carotid artery
Producción CientíficaMissile embolism into the cerebral circulation is a very unusual complication of shotgun wounds to the chest or neck. We
report a case of an 11-year-old boy who sustained an air gunshot wound and pellet embolism to the intracranial carotid
artery. The cerebral artery pellet embolus resulted in contralateral hemiplegia. The patient was successfully treated by
emergency flow reversal and embolectomy. Because this injury is extremely rare, the literature is reviewed, and several
principles are suggested to improve the management. ( J Vasc Surg 2012;55:535-7.
Epidural regional hypothermia for prevention of paraplegia after aortic occlusion : experimental evaluation in a rabbit model
Producción CientíficaThe efficacy of epidural regional hypothermia in the prevention of acute and
delayed-onset paraplegia, as well as possible complications and limitations of this
technique to a clinically acceptable form, were evaluated in 49 New Zealand white rabbits.
Methods: A modified rabbit spinal cord ischemia model of infrarenal aortic occlusion for
30 minutes was employed. The study was performed in two phases. In phase I (n = 20),
regional hypothermia induced by epidural perfusion of iced normal saline solution (4 ~ C)
was tested versus control in 10 rabbits each (groups A and B). In phase II (n = 29) the
animals were subdivided into three groups to study the kinetics of absorption and
distribution of methylene blue (group C; n = 10), radiographic contrast material (group
D; n = 9), and measurement ofcerebrospinal pressure while an epidural iced solution was
or was not infused (group E; n = 10).
Results: At 24 and 48 hours, all of the normothermic animals showed irreversible
paraplegia (Tarlov score 0). In contrast, at 24 hours none of the rabbits undergoing
epidural cold infusion were paraplegic, although at 48 hours one animal had weakness of
a hindiimb (Tarlov score 3). Plasma concentration-time profiles of a continuous epidural
perfusion with methylene blue showed that the spinal canal is a highly compliant space.
Epidurographs showed that epidural perfusion tends to spread more in a cephalic than
caudal direction and the main uptake is by the vascular compartiiient. Despite the large
volumes infused (78.75 ml/hr; range, 50 to 100 ml), we observed only a modest transient
increase in cerebrospinal fluid pressure (from 2.5 -+ 0.3 mm Hg to 5.4 -+ 0.1 mm Hg),
although some animals had intracranial hypertension.
Conclusions: Regional hypothermia induced by epidural cold perfusion has a highly
protective effect against the ischemic spinal cord damage. However, this method probably
does not avoid the risk of delayed-onset paraplegia. An important limitation of this
technique is the difficulty of controlling the intrathecal pressures
Venographic comparison of subcutaneous low-molecular weight heparin with oral anticoagulant therapy in the long-term treatment of deep venous thrombosis
Producción CientíficaPurpose: The primary objective of this study was to evaluate with venography the rate of
thrombus regression after a fixed dose of low–molecular weight heparin (LMWH) per
day for 3 months compared with oral anticoagulant therapy for deep venous thrombosis
(DVT). Secondary endpoints were the comparisons of the efficacy and safety of both
treatments.
Methods: This study was designed as an open randomized clinical study in a university hospital
setting. Of the 165 patients finally enrolled in the study, 85 were assigned LMWH
therapy and 80 were assigned oral anticoagulant therapy. In the group randomized to oral
anticoagulant therapy, the patients first underwent treatment in the hospital with standard
unfractionated heparin and then coumarin for 3 months. Doses were adjusted with
laboratory monitoring to maintain the international normalized ratio between 2.0 and
3.0. Patients in the LMWH group were administered subcutaneous injections of fixed
doses of 40 mg enoxaparin (4000 anti-Xa units) every 12 hours for 7 days, and after discharge
from the hospital, they were administered 40 mg enoxaparin once daily at fixed
doses for 3 months without a laboratory control assay. A quantitative venographic score
(Marder score) was used to assess the extent of the venous thrombosis, with 0 points indicating
no DVT and 40 points indicating total occlusion of all deep veins. The rate of
thrombus reduction was defined as the difference in quantitative venographic scores after
termination of LMWH or coumarin therapy as compared with the scores obtained on the
initial venographic results. The efficacy was defined as the ability to prevent symptomatic
extension or recurrence of venous thromboembolism (documented with venograms or
serial lung scans). The safety was defined as the occurrence of hemorrhages.
Results: After 3 months of treatment, the mean Marder score was significantly decreased
in both groups in comparison with the baseline score, although the effect of therapy was
significantly better after LMWH therapy (49.4% reduction) than after coumarin therapy
(24.5% reduction; P < .001). LMWH therapy and male gender were independently
associated with an enhanced resolution of the thrombus. A lower frequency of symptomatic
recurrent venous thromboembolism was also shown in patients who underwent
treatment with LMWH therapy (9.5%) than with oral anticoagulant therapy (23.7%; P
< .05), although this difference was entirely a result of recurrence of DVT. Bleeding
complications were significantly fewer in the LMWH group than in the coumarin group
(1.1% vs 10%; P < .05). This difference was caused by minor hemorrhages. Coumarin
therapy and cancer were independently associated with an enhanced risk of complications.
Subcutaneous heparin therapy was well tolerated by all patients.
Conclusion: The patients who were allocated to undergo enoxaparin therapy had a significantly
greater improvement in their quantitative venographic score, a significantl
Percutaneous treatment of liver failure and acute mesenteric ischaemia
Producción CientíficaReport: A 67-year-old man with atrial fibrillation developed acute liver failure due to an embolic
occlusion of the CA and SMA, with a severe coagulation disorder. He was successfully managed with
percutaneous stent placement and an exploratory laparotomy was not needed. He remains symptomfree
1 year after the procedure, and duplex follow-up showed stent patency.
Conclusion: Endovascular techniques in patients with liver failure, no signs of peritonism, early diagnosis
and high operative risk seem feasible and should be used if possible, as first-line option
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