On the haplotype diversity along the genome in Spanish beef cattle populations

This study analyzed the haplotype diversity along the genome of seven Spanish Beef Cattle populations within regions of 500 kb using the information provided by the BovineHD Beadchip. The results of the analysis pointed out a strong variability of the haplotype diversity across the genome, which is greatly conserved across populations. This strong concordance between populations suggests that the reasons behind it are intrinsic to the structure of the bovine genome and caused probably by the mutation or recombination rate. Nevertheless, some of the genomic regions with very large haplotype diversity are also due of genome assembly errors

Detección de regiones genómicas con elevado desequilibrio de ligamiento en poblaciones de vacuno de carne españolas con análisis de BovineHD BeadChip

El objetivo de este trabajo fue evaluar el patrón de desequilibrio de ligamiento a lo largo del genoma en siete poblaciones españolas autóctonas de vacuno de carne (Asturiana de los Valles, Avileña Negra-Ibérica, Bruna dels Pirineus, Morucha, Pirenaica, Retinta y Rubia Gallega). Para ello, se utilizó el BovineHD BeadChip con el que se genotiparon 171 tríos formados por individuo/padre/madre. Después del filtrado, se dispuso de 573.134 SNP. A partir de esta información se definió un parámetro que mide el desequilibrio medio del genoma por regiones de 1Mb en cada una de las poblaciones. Los resultados mostraron que el desequilibrio de ligamiento es muy heterogéneo a lo largo del genoma y que, además, esta heterogeneidad es consistente entre poblaciones. Las causas de esta heterogeneidad pueden ser, o bien estructurales y atribuibles a una menor tasa de mutación y/o recombinación, o bien consecuencia de procesos de selección estabilizadora. The objective of this study was to evaluate the pattern of linkage disequilibrium along the genome in seven autochthonous Spanish cattle beef populations (Asturiana de los Valles, Avileña Negra-Ibérica, Bruna dels Pirineus, Morucha, Pirenaica, Retinta and Rubia Gallega). The BovineHD BeadChip was used to genotype 171 trios of individual/sire/dam. 573, 134 SNPs were available after filtering. With this information, a parameter that measures the mean disequilibrium of the genome in regions of 1 Mb in each population was defined. The results show that the linkage disequilibrium is very heterogeneous along the genome, and this heterogeneity is consistent among the considered populations. The causes of this heterogeneity could be structural, and attributed to a lower mutation rate and/or recombination rate, or a result of stabilizing selection

Reducing the environmental impact of surgery on a global scale: systematic review and co-prioritization with healthcare workers in 132 countries

Background Healthcare cannot achieve net-zero carbon without addressing operating theatres. The aim of this study was to prioritize feasible interventions to reduce the environmental impact of operating theatres. Methods This study adopted a four-phase Delphi consensus co-prioritization methodology. In phase 1, a systematic review of published interventions and global consultation of perioperative healthcare professionals were used to longlist interventions. In phase 2, iterative thematic analysis consolidated comparable interventions into a shortlist. In phase 3, the shortlist was co-prioritized based on patient and clinician views on acceptability, feasibility, and safety. In phase 4, ranked lists of interventions were presented by their relevance to high-income countries and low–middle-income countries. Results In phase 1, 43 interventions were identified, which had low uptake in practice according to 3042 professionals globally. In phase 2, a shortlist of 15 intervention domains was generated. In phase 3, interventions were deemed acceptable for more than 90 per cent of patients except for reducing general anaesthesia (84 per cent) and re-sterilization of ‘single-use’ consumables (86 per cent). In phase 4, the top three shortlisted interventions for high-income countries were: introducing recycling; reducing use of anaesthetic gases; and appropriate clinical waste processing. In phase 4, the top three shortlisted interventions for low–middle-income countries were: introducing reusable surgical devices; reducing use of consumables; and reducing the use of general anaesthesia. Conclusion This is a step toward environmentally sustainable operating environments with actionable interventions applicable to both high– and low–middle–income countries

Geomorphology of the Copahue Volcano region and vicinities (Central-western Neuquén)

This thematic map describes the principal features of the landscape, a relative sequence of its geomorphic evolution, and arrives to important conclusions about its regional stratigrapby. The regional landscape is composed and polycyclic. The geoforms are related to different exogenous processes (glacial, fluvial and mass-wasting). An endogenous process (volcanism) formed the more distinctive features; a great tectonic-volcanic caldera and the preglacial Copahue stratovolcano. Some minor and youngest volcanic forms were formed during postglacial times. A previous fluvial cycle was replaced by glacial morphogenesis (valley glaciation) during the Quaternary, due a climatic intervention. A huge and very thick (500-800 m) ice-blister was lodged into the caldera. The ice-blister exceded the caldera's edges forming several glacial diffluences and giving an important and additional supply to neighbouring glacial valleys (Hualcupén and Trocoman), out of to the depression. The Pleistocene glaciation shows two local cycles of volcanic eruptions: pre- and post-glacial. The origin of many local lakes was related to glacial exharation. Others lakes have different genesis: by blocking slide, crater-lake and glacial exharation associated with important structural weakness (Caviahue Lake related to the Trapa-Trapa lineament or Caviahue graben). During postglacial times important rock-avalanches occurred in the Hualcupén valley: the Cajón Chico and Compul rock-avalanches were related to seismic shocks. Previously, their accumulations were interpreted as terminal moraines of a second glaciation. A fluvial rejuvenation phase was the consequence of a blocking of Agrio River by the Agrio volcanic flows, during the Holocene. After that, the river eroded this obstacle restablishing its previous base level. The Agrio cascade represents the upstream present position of the consequent rejuvenation wave. © 2005 Asociación Geológica Argentina

Geomorphologic analysis of the lower and middle section of the drainage basin of the Curri Leuvúriver, Neuquén

The geomorphologic analysis of the study area led to distinguish some formations not considered in previous geological research, as well as to explain the characteristics of the present relief. Thirteen principal geomorphic units produced by different geomorphic processes are recognized. Their variety and incidence through the time are expressed in the glacial morphogenesis concentrated in the western part of the Cordillera del Viento, in the volcanic landscape that predominates in the northern and eastern sectors (calderas, volcanoes, lava flows), in the structural control that defines the morphology of the fluvial process in the central zone and a firstly recognized important landslide to the north of Tricao Malal. As a result of the methodology employed two geological units of different age in the western part of the Tromen-Waile volcanic field were distinguished, which were initially interpreted as a single formation. A limited but consistent structural analysis of the region is also included.Fil:Folguera, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina

Mass wasting in the neuquén cordillera south of 38°: Its trigger factors

The previous analysis of the prehistoric slide phenomena in the main Andes of Neuquén Province in Argentina (36o-38oS), triggered the study of those located south of this la-titude. Therefore a new set of mass wasting deposits has been identified, whose trigger factors and corresponding tectonic framework, where they are located, differ from the northern slides. Their study was performed in three specific areas: Aluminé, Chapelco and Arroyo Limay Chico. Earth flows predominate in relation to slumps. The only exception is the Chapelco rock avalanche. Their occurrence seems to be related to the presence of Limay Chico member of the Caleufú Formation, whose lithology (expanding clays), particular rheology before water saturation, and particular disposition underlying basaltic lava and conglomeradic plains were conditioning factors. The trigger factor of the Present and prehistoric earth flows has been intense orographic precipitations. Water saturation reduced friction and cohesion in materials, incrementing water pore pressure and producing slope instabilities. Rotational slides are related to the slope basal erosion produced by lateral river migration and additionally to precipitations. Slope orientation has been important in determining location of main slides. Lateral slope release through the flanks of glacial valleys due to debutressing because of the glacial retire in the area, has produced instability and rock fracturation that led to slide phenomena. The Chapelco rock avalanche is particularly related to copious precipitations during postglacial times. Thus sliding main trigger factors south of 38oS differ from those pro-posed for the northern area where earthquakes dominated. Their specific age is still unknown, although their geomorphologic analysis allow to constraint a postglacial age for all these occurrences. However, temporal relationships are lacking for the specific case of the arroyo Limay Chico, beyond the glaciated area.Fil:Folguera, A. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina

Geomorphological evolution and relative chronology of terrace levels adjacent to the Chubut river mouth to the Atlantic (Chubut Province)

An ancient alluvial fan and its subsequent evolution are described. Ancient alluvial fan accumulations have been interpreted as the northern continuation of the rodados patagónicos of the Montemayor Plateau, a proposal that is contested. The methodological recognition of the ancient alluvial fan and its genetic and temporary distinction, were made from geomorphologic analysis and altimetric evaluation. Time assignment is a problem not yet solved. The methodology led to three different geomorphic systems or levels related to successive episodes of aggradation and erosion, with increasing lower positions, which coincide with a complex paleodrainage ancient alluvial fan. its successive developments are linked to proposed proto-rivers Chubut 1, 2, 3 and to a Simpson paleo-valley. Despite the mentioned limitations, we propose that the evolutionary model of ancient alluvial fan responds to a structure of cut and fill which is supported by the poly-formational composition of an ancient alluvial fan, and a gradual southward migration of the paleo-drainage. Based on geomorphologic analysis and altimetric distinction an upper level, composed of the remains of three plains (Pa, Pm and Pb), a middle level with two terraces (T1 and T2) and a complex lower level and five terraces (T3, T4, T5 T6 and T7) were recognized. Relict evidences of paleo-drainages are proposed based on the Estancia Paz and Don Morgan-Saraza paleo-valleys in the upper level. The age of the ancient alluvial fan based on the geomorphic evolution of the study area is tentatively assigned to an uncertain period between the late Pleistocene and late Sangamon interglacial at the end of the last glaciation.Fil:di Tommaso, I. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina

Geomorphology of the Moquehue and Aluminé Lakes: Considerations about the Meseta del Arco and Nacimientos del Aluminé calderas

The region is situated in the Neuquén Cordillera at 38° 30'S latitud close to the international border. Geomorphic and structural features are presented which indicated a glacial morphogenesis for the depression that contains the Moquehue- Aluminé lakes. Previous works have identified a large volcanic complex related to Plio-Quaternary volcanic activity located at the east of the present volcanic arc. In this sector various caldera depressions and associated domic bodies have been identified. From the nine proposed calderas only the Pino Hachado caldera has been studied in detail. The Meseta del Arco and Nacimientos del Aluminé are disregarded as calderas. The erosional genesis of the steep scarps previously interpreted as caldera margins is also identified with glacial erosion. Facies and types of the local Pleistocene glaciation, its extension, their flow direction and its quite probable diffluence (Paso del Arco) through coeval glaciers situated north of the international border are also analyzed. Local characteristics of volcanic and eolian morphogenic and the mass-wasting process are described. Brief comments about pre-glacial drainage and the previous proposal of Bío Bío-Aluminé trough on the region are added. Transversal topographic-geological profiles discard west of the Bío Bío-Aluminé Fault a structural unit related to tectonic depression of Bío Bío-Aluminé trough and the Nacimientos del Aluminé and Moquehue calderas.Fil:di Tommaso, I. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina

The "Ñireco Caldera" in the central-western Neuquén Andes (38°50'S - 70°50'O)

In the southern segment of the Copahue- Pino Hachado block, next to the Moquehue-Alumine lacustrine basin, an anomalous concentration of calderas, resulting from a Pliocene-Quaternary volcanic activity was recognized. The Ñireco caldera, which was proposed as part of this caldera complex, is the reason of the present work. The authors object the interpretation of such a morphostructural feature on the basis of a detailed geomorphologic, structural and stratigraphic analyses of the area. The limits of the proposed caldera coincide mostly with fluvial valleys that seem to be controlled by previous structures like faults and regional lineaments. There are no evidences that could suggest the presence of a volcanic complex that theoretically contains such a depression, or for its external and internal flanks. The central sector of the proposed caldera presents the highest altitude values of the region (± 2,900 m a.s.l.), which highly surpass those of the Principal Cordillera at these latitudes. The local stratigraphy of the area, is dominated by the oldest rocks of the region (Upper Paleozoic granitoids and Triassic volcanic and volcaniclastic sequences), and shows not temporal coincidence with the Pliocene-Quaternary volcanic activity, well represented immediately to the north. The study area falls on the contrary into a thick-skinned west-verging fold-and-thrust-belt, where tectonic inversion played a central role.Fil:García Morabito, E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina