Igual, pero diferente: perspectiva institucional de la jura de la Infánta María Isabel Luisa (1833)

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Clergue o laic? Algunes reflexions sobre l'estatus de l'artista i la qüestió de l'autoria a l'Europa romànica

Contribució al I Simposi Científic de l'IEM (Reial Acadèmia de Bones Lletres de Barcelona, 3 de juliol de 2012

Topographic paracentral corneal thickness with pentacam and orbscan: effect of acoustic factor

Purpose: To evaluate the effect of an acoustic factor (AF) on the comparison of central corneal thickness (CCT) and peripheral corneal thickness (PCT) measurements with Orbscan II and Pentacam. Methods: The CCT and PCT at 1, 2, and 3 radial distances from the corneal apex were measured using Orbscan II and Pentacam in 22 right eyes of 22 healthy adults (7 men, 15 women). Three measures were obtained from each 1 of the 25 points measured and then compared to gauge the agreement between both devices at the corneal center and anular areas located at 1-, 2-, and 3-mm distances from the central measurement. Orbscan II readings were considered with and without an AF correction. Results: Pentacam provides statistically significant higher values than Orbscan II does at all the 25 locations analyzed (P,0.001). With a few exceptions, the average difference was fairly constant between 20 and 40 mm for all the corneal locations. A high correlation existed between central readings (r2=0.927; P,0.001) and average thickness at each one of the annular areas being analyzed (r2=0.897 at 1 mm, r2=0.876 at 2 mm, and r2=0.870 at 3 mm); Pentacam minus Orbscan II value averaged for all the points changed from 228610 to 22269 mm after the removal of the AF in Orbscan II. Conclusions: Central and peripheral measurements of the corneal thickness obtained with Orbscan II and Pentacam are significantly different. The removal of the AF in Orbscan II renders lower mean differences but decreases the agreement between both systems and potentially induces an overestimation of CCT and PCT by Orbsan II compared with Pentacam.Supported by national grant PI081380 from Instituto de Salud Carlos III, Spain granted to Ocular Surface and Contact Lens Research Group GI-1750

Long-term changes in corneal structure and tear inflammatory mediators after orthokeratology and LASIK

PURPOSE: To monitor changes in corneal structure and level of inflammatory mediators in tears of myopic patients following orthokeratology (OK) and laser in situ keratomileusis (LASIK). METHODS: Sixty-two myopic subjects were analyzed in this prospective study. Thirty-two had worn Paragon CRT contact lenses and 30 underwent standard LASIK. Thirty-two control subjects were also recruited. Pachometry and corneal topography were performed 12 months after both interventions. Tears were collected and assayed using ELISA for IL-6, IL-8, matrix metalloproteinase-9 (MMP-9), and epidermal growth factor (EGF). RESULTS: Corneal power decreased in the central area and increased in the paracentral area. Simultaneously, there was a central corneal thinning with mid-peripheral thickening for OK. No changes were observed for LASIK. In comparison with controls, IL-6, IL-8, MMP-9, and EGF levels were increased significantly for OK (P < 0.01). Only MMP-9 (P < 0.01) and EGF (P < 0.01) were increased for LASIK. Pro-inflammatory response was found to be associated with the degree of myopia in the OK group. The MMP-9 and EGF upregulation was linked to the presence of iron deposition in both groups, whereas increased levels of EGF were connected with the presence of myopic regression after LASIK. CONCLUSIONS: Both interventions involved important tissue reshaping. The physical presence of a reverse geometry contact lens caused certain markers to change significantly in comparison with no lens wear or LASIK in the long-term response. MMP-9 was significantly higher in tears of subjects presenting iron deposition after OK or LASIK, and EGF levels seemed to play an important role in postoperative refractive outcomes after LASIK.Supported by National Grant PI081380 from Instituto de Salud Carlos III, Spain, awarded to the Ocular Surface and Contact Lens Research Group GI-1750

Pigmented corneal ring associated with orthokeratology in caucasians : case reports

BACKGROUND: The aim was to report the appearance of a pigmented ring in both eyes of two patients undergoing overnight orthokeratology. METHODS: Two Caucasian patients, one male and one female, were fitted with orthokeratology lenses to correct myopia between -2.00 and -2.50 DS with Paragon corneal refractive therapy lenses worn overnight. Treatment was successful in both patients achieving uncorrected vision of 6/6 or better monocularly under high (100 per cent) and low (10 per cent) contrast conditions. RESULTS: At the six-month visit both patients presented with pigmented rings under slitlamp examination in both eyes. The location of the ring was consistent with the corneal area being flattened for myopic correction. Clinical examination was otherwise normal. CONCLUSIONS: Despite being initially reported in Asian patients from Hong Kong, a pigmented ring related to orthokeratology treatment is also present in Caucasian patients, reducing the potential role of an ethnic link. Further large-scale studies need to be done to estimate the actual incidence of this condition and the potential implications for corneal health

What is the best alternative to the use of cycloplegic in the objective refraction

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