From E_8 to F via T

We argue that T-duality and F-theory appear automatically in the E_8 gauge bundle perspective of M-theory. The 11-dimensional supergravity four-form determines an E_8 bundle. If we compactify on a two-torus, this data specifies an LLE_8 bundle where LG is a centrally-extended loopgroup of G. If one of the circles of the torus is smaller than sqrt(alpha') then it is also smaller than a nontrivial circle S in the LLE_8 fiber and so a dimensional reduction on the total space of the bundle is not valid. We conjecture that S is the circle on which the T-dual type IIB theory is compactified, with the aforementioned torus playing the role of the F-theory torus. As tests we reproduce the T-dualities between NS5-branes and KK-monopoles, as well as D6 and D7-branes where we find the desired F-theory monodromy. Using Hull's proposal for massive IIA, this realization of T-duality allows us to confirm that the Romans mass is the central extension of our LE_8. In addition this construction immediately reproduces the conjectured formula for global topology change from T-duality with H-flux.Comment: 25 pages, 4 eps figure

Camera calibration in sport event scenarios

The main goal of this paper is the design of a novel and robust methodology for calibrating cameras from a single image in sport scenarios, such as a soccer field, or a basketball or tennis court. In these sport scenarios, the only references we use to calibrate the camera are the lines and circles delimiting the different regions. The first problem we address is the extraction of image primitives, including the challenging problems of shaded regions and lens distortion. From these primitives, we automatically recognise the location of the sport court in the scene by estimating the homography which matches the actual court with its projection onto the image. This is achieved even when only a few primitives are available. Finally, from this homography, we recover the camera calibration parameters. In particular, we estimate the focal length as well as the position and orientation in the 3D space. We present some experiments on models and real courts which illustrate the accuracy of the proposed methodology

Cord blood Lin(-)CD45(-) embryonic-like stem cells are a heterogeneous population that lack self-renewal capacity.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Human umbilical cord blood (hUCB) has been proposed to contain not only haematopoietic stem cells, but also a rare pluripotent embryonic-like stem cell (ELSc) population that is negative for hematopoietic markers (Lin(-)CD45(-)) and expresses markers typical of pluripotent cells. The aim of this work was to isolate, characterise and expand this ELSc fraction from hUCB, as it may provide a valuable cell source for regenerative medicine applications. We found that we could indeed isolate a Lin(-)CD45(-) population of small cells (3-10 µm diameter) with a high nucleus to cytoplasm ratio that expressed the stem cell markers CD34 and CXCR4. However, in contrast to some previous reports, this fraction was not positive for CD133. Furthermore, although these cells expressed transcripts typical of pluripotent cells, such as SOX2, OCT3/4, and NANOG, they were not able to proliferate in any of the culture media known to support stem cell growth that we tested. Further analysis of the Lin(-)CD45(-) population by flow cytometry showed the presence of a Lin(-)CD45(-)Nestin(+) population that were also positive for CD34 (20%) but negative for CXCR4. These data suggest that the Lin(-)CD45(-) stem cell fraction present in the cord blood represents a small heterogeneous population with phenotypic characteristics of stem cells, including a Lin(-)CD45(-)Nestin(+) population not previously described. This study also suggests that heterogeneity within the Lin(-)CD45(-) cell fraction is the likely explanation for differences in the hUCB cell populations described by different groups that were isolated using different methods. These populations have been widely called "embryonic-like stem cell" on the basis of their phenotypical similarity to embryonic stem cells. However, the fact they do not seem to be able to self-renew casts some doubt on their identity, and warns against defining them as "embryonic-like stem cell" at this stage.Anthony Nolan and the Great Ormond Street Hospital Charity for financial support. Cesar Alvarez-Gonzalez is a fellowship from Consejo Nacional de Ciencia y Tecnologia (CONACyT) and Instituto Jaliscience de la Juventud (IJJ); Mexico

Wind-induced Cross-Strait Sea Level Variability in the Strait of Gibraltar using Coastal Altimetry and In-Situ Measurements

In this work, we retracked altimeter waveforms of ESA satellites. ERS2 RA and Envisat RA2 from descending track 0360 over the eastern side of the Strait of Gibraltar using the Adaptive Leading Edge Subwaveform ALES retracker

On fermionic tilde conjugation rules and thermal bosonization. Hot and cold thermofields

A generalization of Ojima tilde conjugation rules is suggested, which reveals the coherent state properties of thermal vacuum state and is useful for the thermofield bosonization. The notion of hot and cold thermofields is introduced to distinguish different thermofield representations giving the correct normal form of thermofield solution for finite temperature Thirring model with correct renormalization and anticommutation properties.Comment: 13 page

Reticulocyte Maturation Parameters Are Reliable Early Predictors of Hematopoietic Engraftment after Allogeneic Stem Cell Transplantation

AbstractEarly detection of donor-derived hematopoietic restoration after allogeneic stem cell transplantation (allo-SCT) is a crucial issue in the management of heavily immunocompromised patients. The aim of this prospective study was to validate our previously defined cutoff values for reticulocyte maturation parameters as early predictors of hematopoietic engraftment. Importantly, the effect of clinical variables in reticulocyte engraftment was also sought. For this purpose, we prospectively studied 136 consecutive patients undergoing allo-SCT from related (n = 89) or unrelated (n = 47) donors. High fluorescence reticulocytes (RETH), immature reticulocyte fraction (IRF), mean fluorescence index (MFI), and mean reticulocyte volume (MRV) were automatically measured in peripheral blood samples drawn on a daily basis. We previously defined reticulocyte engraftment when MFI ≥10, RETH ≥3%, IRF ≥10%, and MRV ≥110 fL. Median neutrophil engraftment was 18 days (range, 10-35 days); for reticulocyte parameters, the values were 14 days for IRF (range, 7-45 days), 14 days for MFI (range, 7-43 days), 15 days for RETH (range, 7-43 days), and 21 days for MRV (range, 9-74 days). These differences reached statistical significance for MFI and IRF when compared with standard neutrophil recovery, even when analyzing siblings or unrelated donors separately. In univariate analysis, donor-recipient ABO disparity adversely influenced erythroid engraftment (P = .04 for IRF, P = .03 for MFI), but the infusion of >2.9 × 106/kg of CD34+ cells was associated with a shorter time to reach erythroid engraftment (P = .02 for IRF and MFI). In Cox regression analysis, ≥100/μL neutrophils and IRF ≥10% were predictive parameters for standard neutrophil engraftment. Based on these findings, we suggest that serial measurement of IRF or MFI should be routinely used to trace hematopoietic restoration after allo-SCT because these preceded standard neutrophil recovery by a median of 4 days and are therefore very useful to make clinical decisions