1,647 research outputs found
Benefits of Vine Leaf on Different Biological Systems
For centuries, the therapeutic benefits of grapes and other byproducts have been empirically used for medical purposes such as bleeding, pain, inflammation, nausea, diarrhea, gastroenteritis, or skin diseases. Moderated intake of the red wine improves parameters as blood lipids, endothelial dysfunction, platelet aggregation, and other risk factors for cardiovascular disease. However, few studies have been explored the potential benefits from vine byproducts. Vine leaves, a waste product from the vine, are also rich source of polyphenols and other therapeutic compounds. In this chapter, we explored the therapeutic properties from vine leaf in different biological systems
Impacts of pure shocks in the BHR71 bipolar outflow
During the formation of a star, material is ejected along powerful jets that
impact the ambient material. This outflow regulates star formation by e.g.
inducing turbulence and heating the surrounding gas. Understanding the
associated shocks is therefore essential to the study of star formation. We
present comparisons of shock models with CO, H2, and SiO observations in a
'pure' shock position in the BHR71 bipolar outflow. These comparisons provide
an insight into the shock and pre-shock characteristics, and allow us to
understand the energetic and chemical feedback of star formation on Galactic
scales. New CO (Jup = 16, 11, 7, 6, 4, 3) observations from the shocked regions
with the SOFIA and APEX telescopes are presented and combined with earlier H2
and SiO data (from the Spitzer and APEX telescopes). The integrated intensities
are compared to a grid of models that were obtained from a
magneto-hydrodynamical shock code which calculates the dynamical and chemical
structure of these regions combined with a radiative transfer module based on
the 'large velocity gradient' approximation. The CO emission leads us to update
the conclusions of our previous shock analysis: pre-shock densities of 1e4 cm-3
and shock velocities around 20-25 km s-1 are still constrained, but older ages
are inferred ( 4000 years). We evaluate the contribution of shocks to the
excitation of CO around forming stars. The SiO observations are compatible with
a scenario where less than 4% of the pre-shock SiO belongs to the grain
mantles. We infer outflow parameters: a mass of 1.8x1e-2 Msun was measured in
our beam, in which a momentum of 0.4 Msun km s-1 is dissipated, for an energy
of 4.2x1e43erg. We analyse the energetics of the outflow species by species.
Comparing our results with previous studies highlights their dependence on the
method: H2 observations only are not sufficient to evaluate the mass of
outflows.Comment: 14 pages, 10 figures, 4 Tables, accepted in A&
Evolution of tolerance to PCBs and susceptibility to a bacterial pathogen (\u3cem\u3eVibrio harveyi\u3c/em\u3e) in Atlantic killifish (\u3cem\u3eFundulus heteroclitus\u3c/em\u3e) from New Bedford (MA, USA) harbor
A population of the non-migratory estuarine fish Fundulus heteroclitus (Atlantic killifish) resident to New Bedford (NB), Massachusetts, USA, an urban harbor highly contaminated with polychlorinated biphenyls (PCBs), demonstrates recently evolved tolerance to some aspects of PCB toxicity. PCB toxicology, ecological theory, and some precedence supported expectations of increased susceptibility to pathogens in NB killifish. However, laboratory bacterial challenges of the marine pathogen Vibrio harveyi to wild fish throughout the reproductive season and to their mature laboratory-raised progeny demonstrated comparable survival by NB and reference killifish, and improved survival by NB males. These results are inconsistent with hypothesized trade-offs of adaptation, and suggest that evolved tolerance in NB killifish may include mechanisms that minimize the immunosuppressive effects of PCBs. Compensatory strategies of populations persisting in highly contaminated environments provide a unique perspective for understanding the long-term ecological effects of toxic chemicals
Splitting of Long-Period Comet C/2018 F4 (PANSTARRS)
Long-period comet C/2018 F4 (PANSTARRS) was observed to show duplicity of its
inner region in 2020 September, suggestive of a splitting event. We here
present analyses of our observations of the comet taken from the LOOK project
and the University of Hawaii 2.2 m telescope after the discovery of the
splitting. The two fragments Components A and B, estimated to be m
to 4 km in radius, remained highly similar to each other in terms of
brightness, colour, and dust morphology throughout our observing campaign from
2020 September to 2021 December. Our fragmentation model yielded that the two
components split at a relative speed of m s in 2020 late
April, implying a specific energy change of J kg, and that Component B was subjected to a stronger
nongravitational acceleration than Component A in both the radial and normal
directions of the orbit. The obtained splitting time is broadly consistent with
the result from the dust morphology analysis, which further suggested that the
dominant dust grains were millimeter-sized and ejected at speed m
s. We postulate that the pre-split nucleus of the comet consisted of two
lobes resembling the one of 67P, or that the comet used to be a binary system
like main-belt comet 288P. Regardless, we highlight the possibility of using
observations of split comets as a feasible manner to study the bilobate shape
or binarity fraction of cometary nuclei.Comment: Accepted to AJ for publicatio
Librarians as Natural Disaster Stress Response Facilitators: Building Evidence for Trauma-Informed Library Education and Practice
Public librarians are on the front line of catastrophic events that, each year, leave millions
of people with significant mental health consequences; in the midst of these tragedies, librarians
are often called upon to address community needs, often while neglecting their personal
hardships. In this paper, we propose research, education, and practice opportunities centered on
SOLAR, a community-based therapeutic approach that will allow librarians to recognize and
assist patrons with symptoms just short of post-traumatic stress disorder (PTSD) related to
natural disasters. This proposed therapy offers public librarians an opportunity to engage with a
treatment framework to meaningfully support their patrons while benefiting from the self-care
often overlooked in times of crisis. This work may be a template for contextually sensitive,
community-facilitated mental health services critical for communities that lack financial and
geographical access to larger health infrastructures. We include opportunities for research in
librarians’ trauma response to inform public librarians’ education and practice to improve
disaster preparedness and community well-being
Update on indications, complications, and outcomes of scleral contact lenses
Background: The role of scleral contact lenses (SCLs) has increasingly expanded since the first lens was fitted more than a century ago. While it was initially prescribed for the management of severely compromised corneas, the indications for modern SCL use have expanded to include less severe diseases. In this review, we aimed to provide an up-to-date overview of the current indications, complications, and outcomes for the various types of SCLs.
Methods: In this narrative review, we thoroughly searched the PubMed/MEDLINE database for literature published from January 1980 to November 2021. Only relevant up-to-date English references were included. Furthermore, the figures in this manuscript were derived from our unit’s patient documentation.
Results: Currently, SCLs can successfully be used to manage ocular surface diseases, visually rehabilitate irregular corneas, and correct irregular refractive errors. Although newer materials have yielded the same visual outcomes with fewer complications, these consequences still occur in approximately one-third of contact lens wearers, including difficulties in insertion and/or removal, discomfort or pain, and developing either halos, blurriness, or haze. Even though most of these complications are minor and can be easily treated, a good practice is essential to avoid sight-threatening complications such as microbial keratitis.
Conclusions: SCLs are indispensable in ophthalmic clinics. The development of better-quality SCLs has increased the number of indications and improved the achievable visual rehabilitation. The future of developing improvements in SCL design, materials, and fit, and the expansion of their indication range is promising
Human iPSC-Derived Cardiomyocytes of Peripartum Patients With Cardiomyopathy Reveal Aberrant Regulation of Lipid Metabolism
Fetal and childhood growth patterns associated with bone mass in school-age children: The generation R study
Low birth weight is associated with lower bone accrual in children and peak bone mass in adults. We assessed how different patterns of longitudinal fetal and early childhood growth influence bone properties at school age. In 5431 children participating in a population-based prospective cohort study, we measured fetal growth by ultrasound at 20 and 30 weeks gestation, and childhood growth at birth, 1, 2, 3, and 4 years of age. We analy
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