Enhanced Antibacterial Property by the Synergetic Effect of TiO2 and ZnO Nano-Particles in Biodegradable Hydrogel

In this study, three types of nanocomposite hydrogel were produced by free radical polymerization and chemical bath deposition technique together. TiO2 nanoparticles (NPs) have been incorporated in polymeric matrices in order to provide antimicrobial activity to the biodegradable hydrogel. Then, ZnO NPs have been deposited on the surface of the hydrogel to improve antibacterial activity. Structural and antibacterial properties of above nanocomposites were fully determined by X-Ray diffractometer (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Field Emission Scanning Electron Microscopy (FESEM), Energy Dispersive X-Ray Spectrometer (EDX), and ASTME-2149 methods. At the reaction time of 60 minutes, nanoZnO particles on hydrogel were fully developed. Zn content of hydrogel was 35.89 at. %, Ti content of hydrogel was also determined as 0.16 at.%. In respect to antibacterial activity tests results, Escherichia coli were more resistant to hydrogel and ZnO nanoflower than Staphylococcus aureus

Effects of Deposition Time on Structural and Morphological Properties of Synthesized ZnO Nanoflowers Without Using Complexing Agent

ZnO nanoflowers have been synthesized by chemical bath deposition technique at different deposition times without using complexing agent, so it is an environmentalist study. Effects of deposition time on structural and morphological properties of ZnO nanoflowers have been investigated by Xray diffraction (XRD) method and Field Emission Scanning Electron Microscope (FESEM). XRD patterns showed that the samples had hexagonal wurtzite structure and polycrystalline nature. Grain sizes, dislocation densities and lattice parameters of the samples have been calculated. According to these results, it has been determined that the ZnO nanoflowers synthesized in very short time like 30 minutes without using complexing agent, showed the best crystallization. When the images of ZnO nanoflowers have been examined, it has seen that the structure is formed continuously and independently from each other by nanorods. It has also seen that these nanorods combine to form a flower-like structure

Novel multifunctional colloidal carbohydrate nanofiber electrolytes with excellent conductivity and responses to bone cancer cells

Gokmen, Fatma Ozge/0000-0002-5548-8790WOS: 000361920900075PubMed: 26344321This work presents a new approach to fabricating novel polymer nanofiber composites (NFCs) from water solution blends of PVA (hydrolyzed 89%)/ODA-MMT and Na-CMC/ODA-MMT nanocomposites as well as their folic acid (FA) incorporated modifications (NC-3-FA and NC-4-FA) through green electrospinning nanotechnology. The chemical and physical structures and surface morphology of the nanofiber composites were confirmed. Significant improvements in nanofiber morphology and size distribution of the NFC-3-FA and NFC-4-FA nanofibers with lower average means 110 and 113 nm compared with those of NFC-1/NFC-2 nanofibers (270 and 323 nm) were observed. The structural elements of polymer NFCs, particularly loaded partner NC-2, plays an important role in chemical and physical interfacial interactions, phase separation processing and enables the formation of nanofibers with unique morphology and excellent conductivity (NFC-3-FA 3.25 x 10(-9) S/cm and NFC-4-FA 8.33 x 10(-4) S/cm). This is attributed to the higher surface contact areas and multifunctional self-assembled supramacromolecular nanostructures of amorphous colloidal electrolytes. The anticancer activity of FA-containing nanofibers against osteocarcinoma cells were evaluated by cytotoxicity, apoptotic and necrotic analysis methods. (C) 2015 Elsevier Ltd. All rights reserved.Turkish Scientific and Technological Research Council (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [TBAG-HD/249, BIDEB-PD/2218]The authors would like to acknowledge the Turkish Scientific and Technological Research Council (TUBITAK) for the financial support of this work through postdoctoral projects TBAG-HD/249 and BIDEB-PD/2218

International Nosocomial Infection Control Consortium (INICC) national report on device-associated infection rates in 19 cities of Turkey, data summary for 2003-2012

Background: Device-associated healthcare-acquired infections (DA-HAI) pose a threat to patient safety, particularly in the intensive care unit (ICU). We report the results of the International Infection Control Consortium (INICC) study conducted in Turkey from August 2003 through October 2012

International Nosocomial Infection Control Consortiu (INICC) report, data summary of 43 countries for 2007-2012. Device-associated module

We report the results of an International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2007-December 2012 in 503 intensive care units (ICUs) in Latin America, Asia, Africa, and Europe. During the 6-year study using the Centers for Disease Control and Prevention's (CDC) U.S. National Healthcare Safety Network (NHSN) definitions for device-associated health care–associated infection (DA-HAI), we collected prospective data from 605,310 patients hospitalized in the INICC's ICUs for an aggregate of 3,338,396 days. Although device utilization in the INICC's ICUs was similar to that reported from ICUs in the U.S. in the CDC's NHSN, rates of device-associated nosocomial infection were higher in the ICUs of the INICC hospitals: the pooled rate of central line–associated bloodstream infection in the INICC's ICUs, 4.9 per 1,000 central line days, is nearly 5-fold higher than the 0.9 per 1,000 central line days reported from comparable U.S. ICUs. The overall rate of ventilator-associated pneumonia was also higher (16.8 vs 1.1 per 1,000 ventilator days) as was the rate of catheter-associated urinary tract infection (5.5 vs 1.3 per 1,000 catheter days). Frequencies of resistance of Pseudomonas isolates to amikacin (42.8% vs 10%) and imipenem (42.4% vs 26.1%) and Klebsiella pneumoniae isolates to ceftazidime (71.2% vs 28.8%) and imipenem (19.6% vs 12.8%) were also higher in the INICC's ICUs compared with the ICUs of the CDC's NHSN