Displasia Ectodérmica Anhidrótica

El presente trabajo tiene por finalidad difundir el caso clínico de una displasia ectodérmica anhidrótica con importantes manifestaciones bucales. Esta enfermedad se caracteriza por la ausencia o la disminución del pelo, dientes, uñas, glándulas sudoríparas y sebáceas, anomalías de la nariz, pabellones auriculares, labios y sistema dentario, signos que acompañan a trastornos del sistema nervioso central.La displasia ectodérmica anhidrótica, se trata de un síndrome heredo familiar, transmitido como un rasgo recesivo ligado al cromosoma X, que afecta en el 90% de los casos a los varones. El resto corresponde a mujeres portadoras que presentan sintomatología escasa.El reconocimiento de las manifestaciones clínicas generales y bucales nos permitirá instituir una conducta terapéutica adecuada

Global overview of the management of acute cholecystitis during the COVID-19 pandemic (CHOLECOVID study)

Background: This study provides a global overview of the management of patients with acute cholecystitis during the initial phase of the COVID-19 pandemic. Methods: CHOLECOVID is an international, multicentre, observational comparative study of patients admitted to hospital with acute cholecystitis during the COVID-19 pandemic. Data on management were collected for a 2-month study interval coincident with the WHO declaration of the SARS-CoV-2 pandemic and compared with an equivalent pre-pandemic time interval. Mediation analysis examined the influence of SARS-COV-2 infection on 30-day mortality. Results: This study collected data on 9783 patients with acute cholecystitis admitted to 247 hospitals across the world. The pandemic was associated with reduced availability of surgical workforce and operating facilities globally, a significant shift to worse severity of disease, and increased use of conservative management. There was a reduction (both absolute and proportionate) in the number of patients undergoing cholecystectomy from 3095 patients (56.2 per cent) pre-pandemic to 1998 patients (46.2 per cent) during the pandemic but there was no difference in 30-day all-cause mortality after cholecystectomy comparing the pre-pandemic interval with the pandemic (13 patients (0.4 per cent) pre-pandemic to 13 patients (0.6 per cent) pandemic; P = 0.355). In mediation analysis, an admission with acute cholecystitis during the pandemic was associated with a non-significant increased risk of death (OR 1.29, 95 per cent c.i. 0.93 to 1.79, P = 0.121). Conclusion: CHOLECOVID provides a unique overview of the treatment of patients with cholecystitis across the globe during the first months of the SARS-CoV-2 pandemic. The study highlights the need for system resilience in retention of elective surgical activity. Cholecystectomy was associated with a low risk of mortality and deferral of treatment results in an increase in avoidable morbidity that represents the non-COVID cost of this pandemic

XXVI Congreso Nacional y II Congreso Internacional de SEDEM

Organizan: Sociedad Española de Educación Médica y Facultad de Medicina y Enfermería, Universidad del País Vasco (UPV/EHU)Comunicaciones aceptadas en el XXVI Congreso de la Sociedad Española de Educación Médica, celebrado en Bilbao del 28 al 30 de noviembre de 2024

Oxidation of the turbine blade material CMSX4 studied by x-ray diffraction

The high-temperature oxidation behaviour of the turbine blade material CMSX4 was examined by in situ X-ray diffraction in the temperature range between 700 and 1200°C. The intensities of the X-ray reflections of the oxides formed during the oxidation process were calculated and plotted as functions of time. Their curves show the oxidation process. After cooling down an ex situ electron microprobe analysis was carried out to determine the site of the oxidation products within the oxide scale. The results reveal that CMSX4 changes its oxidation behaviour between 900 and 1000°C due to the solution of the γ'-phase. The presentation shows how in situ X-ray diffraction and electron microprobe form a complementary combination.L'oxydation des pales de turbine en CMSX4 à haute température est examinée avec la diffraction in situ des rayons X entre 700 et 1200°C. Les intensités des raies des oxydes sont calculées et tracées en fonction du temps. Après refroidissement, une microanalyse est utilisée pour déterminer les produits d'oxydation dans la couche d'oxyde. Le CMSX4 montre un changement de comportement entre 900 et 1000°C à cause de la dissolution de la phase γ'. Cette présentation démontre que la diffraction des rayons X in situ et la microanalyse X sont deux méthodes complémentaires