Research Into Tennessee\u27s Achievement School District: Autonomy, Incentives, and Guidance for Providers

This is the first in a series of reports based on a multi-year research project on the Tennessee Achievement School District (ASD). The purpose of these reports is to present independent analyses based on evidence, as well as the experience and judgment of the research team. The current discussion examines the ASD’s theory of action, and considers how its system of accountability and guidance could influence the nature of students’ educational experiences. Particular attention is given to the diversity of approaches among the organizations operating schools in the ASD, and the extent to which this could lead to meaningful comparisons, discussion, and ultimately organizational learning. Our focus on organizational learning is motivated by the belief that the capacity of ASD providers to learn and improve is critical to the success of the overall enterprise

Osteoblastoma of the thyroid cartilage treated with voice preserving laryngeal framework resection

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/99105/1/lary23972.pd

A lean neck mass clinic model: Adding value to care

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/115945/1/lary25535.pd

Does drug‐induced sleep endoscopy predict surgical success in transoral robotic multilevel surgery in obstructive sleep apnea?

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/136419/1/lary26255_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/136419/2/lary26255.pd

Bringing Upstairs Care Downstairs; Integration of Rehabilitation Medicine, Care Management, and the Hospital Elder Life Program (HELP) into an Emergency Department.

Introduction: Services such as physical therapy (PT), occupational therapy (OT), speech-language pathology (SLP), social work (SW), care management, and elder life specialists have long been an established part of care for patients admitted to Maine Medical Center (MMC) but not for patients in the Emergency Department (ED). Methods and Results: Driven in part by changes in Medicare reimbursement models, care management established a presence in the Emergency Department (ED) in 2003 with a focus on care planning and cost avoidance. In recent years PT, OT, SLP, SW, and the Hospital Elder Life Program (HELP) have increased their ED involvement substantially. These services not only support care management decisions but have become an invaluable part of the ED team. The timing, staffing models, and roles of these services in our emergency department are described. Discussion: There was strong leadership support to create these positions in the ED. Increased patient volume hospital wide has required staffing flexibility. Initial concerns for slowing the ED where anecdotally resolved. Other hospitals in our system are interested in this approach. Conclusions: While the value of this work feels self-evident and is already established for admitted patients, descriptive and outcome-oriented studies for ED patients would be enlightening

Pathologic gene network rewiring implicates PPP1R3A as a central regulator in pressure overload heart failure

Heart failure is a leading cause of mortality, yet our understanding of the genetic interactions underlying this disease remains incomplete. Here, we harvest 1352 healthy and failing human hearts directly from transplant center operating rooms, and obtain genome-wide genotyping and gene expression measurements for a subset of 313. We build failing and non-failing cardiac regulatory gene networks, revealing important regulators and cardiac expression quantitative trait loci (eQTLs). PPP1R3A emerges as a regulator whose network connectivity changes significantly between health and disease. RNA sequencing after PPP1R3A knockdown validates network-based predictions, and highlights metabolic pathway regulation associated with increased cardiomyocyte size and perturbed respiratory metabolism. Mice lacking PPP1R3A are protected against pressure-overload heart failure. We present a global gene interaction map of the human heart failure transition, identify previously unreported cardiac eQTLs, and demonstrate the discovery potential of disease-specific networks through the description of PPP1R3A as a central regulator in heart failure

Status of the James Webb Space Telescope Integrated Science Instrument Module System

The Integrated Science Instrument Module (ISIM) of the James Webb Space Telescope (JWST) is discussed from a systems perspective with emphasis on development status and advanced technology aspects. The ISIM is one of three elements that comprise the JWST space vehicle and is the science instrument payload of the JWST. The major subsystems of this flight element and their build status are described