12,936 research outputs found

    Being Healthy: a Grounded Theory Study of Help Seeking Behaviour among Chinese Elders living in the UK

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    The health of older people is a priority in many countries as the world’s population ages. Attitudes towards help seeking behaviours in older people remain a largely unexplored field of research. This is particularly true for older minority groups where the place that they have migrated to presents both cultural and structural challenges. The UK, like other countries,has an increasingly aging Chinese population about who relatively little is known. This study used a qualitative grounded theory design following the approach of Glaser (1978). Qualitative data were collected using semi-structured interviews with 33 Chinese elders who were aged between 60 and 84, using purposive and theoretical sampling approaches. Data were analysed using the constant comparative method until data saturation occurred and a substantive theory was generated. ‘Being healthy’ (the core category) with four interrelated categories: self-management, normalizing/minimizing, access to health services, and being cured form the theory. The theory was generated around the core explanations provided by participants and Chinese elders’ concerns about health issues they face in their daily life. We also present data about how they direct their health-related activities towards meeting their physical and psychological goals of being healthy. Their differential understanding of diseases and a lack of information about health services were potent predictors of nonïżœhelp seeking and ‘self’ rather than medical management of their illnesses. This study highlights the need for intervention and health support for Chinese elders

    Broadband Relaxation-Optimized Polarization Transfer in Magnetic Resonance

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    Many applications of magnetic resonance are limited by rapid loss of spin coherence caused by large transverse relaxation rates. In nuclear magnetic resonance (NMR) of large proteins, increased relaxation losses lead to poor sensitivity of experiments and increased measurement time. In this paper we develop broadband relaxation optimized pulse sequences (BB-CROP) which approach fundamental limits of coherence transfer efficiency in the presence of very general relaxation mechanisms that include cross-correlated relaxation. These broadband transfer schemes use new techniques of chemical shift refocusing (STAR echoes) that are tailored to specific trajectories of coupled spin evolution. We present simulations and experimental data indicating significant enhancement in the sensitivity of multi-dimensional NMR experiments of large molecules by use of these methods

    Influential factors of aligning Spotify squads in mission-critical and offshore projects – a longitudinal embedded case study

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    Changing the development process of an organization is one of the toughest and riskiest decisions. This is particularly true if the known experiences and practices of the new considered ways of working are relative and subject to contextual assumptions. Spotify engineering culture is deemed as a new agile software development method which increasingly attracts large-scale organizations. The method relies on several small cross-functional self-organized teams (i.e., squads). The squad autonomy is a key driver in Spotify method, where a squad decides what to do and how to do it. To enable effective squad autonomy, each squad shall be aligned with a mission, strategy, short-term goals and other squads. Since a little known about Spotify method, there is a need to answer the question of: How can organizations work out and maintain the alignment to enable loosely coupled and tightly aligned squads? In this paper, we identify factors to support the alignment that is actually performed in practice but have never been discussed before in terms of Spotify method. We also present Spotify Tailoring by highlighting the modified and newly introduced processes to the method. Our work is based on a longitudinal embedded case study which was conducted in a real-world large-scale offshore software intensive organization that maintains mission-critical systems. According to the confidentiality agreement by the organization in question, we are not allowed to reveal a detailed description of the features of the explored project

    The Glassy Wormlike Chain

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    We introduce a new model for the dynamics of a wormlike chain in an environment that gives rise to a rough free energy landscape, which we baptise the glassy wormlike chain. It is obtained from the common wormlike chain by an exponential stretching of the relaxation spectrum of its long-wavelength eigenmodes, controlled by a single stretching parameter. Predictions for pertinent observables such as the dynamic structure factor and the microrheological susceptibility exhibit the characteristics of soft glassy rheology and compare favourably with experimental data for reconstituted cytoskeletal networks and live cells. We speculate about the possible microscopic origin of the stretching, implications for the nonlinear rheology, and the potential physiological significance of our results.Comment: 12 pages, 8 figures. Minor correction

    How high the temperature of a liquid be raised without boiling?

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    How high the temperature of a liquid be raised beyond its boiling point without vaporizing (known as the limit of superheat) is an interesting subject of investigation. A new method of finding the limit of superheat of liquids is presented here. The superheated liquids are taken in the form of drops suspended in visco elastic gel. The nucleation is detected acoustically by a sensitive piezo-electric transducer, coupled to a multi channel scaler and the nucleation is observed as a funtion of time and with increase of temperature. The limit of superheat measured by the present method supersedes all other measurements and theoretical predictions in reaching closest to the critical temperature and warrants improved theoretical predictions.Comment: 10 pages, 1 fig. Phys, Rev. E. (2000) in pres

    Experimental results on radiation-induced bulk damage effects in float-zone and epitaxial silicon detectors

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    A comparative study of the radiation hardness of silicon pad detectors, manufactured from Float-Zone and Epitaxial n-type monocrystals and irradiated with protons and neutrons up to a fluence of 3.5 1014 cm-2 is presented. The results are compared in terms of their reverse current, depletion voltage, and charge collection as a function of fluence during irradiation and as a function of time after irradiation

    Study of charge collection and noise in non-irradiated and irradiated silicon detectors

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    The large collection and noise were studied in non-irradiated and irradiated silicon detectors as a function of temperature (T), shaping time (0) and fluence , up to about 1,2 x 10(14) protons per cm2 for minimum-ionizing electrons yielded by a 106 Ru source. The noise of irradiated detectors is found to be dominted for short shaping times (Ÿ50ns) by a series noise compo- nent, while for longer shaping times (80ns) a parallel noise component (correlated with the reverse current) prevails. For non-irradiated detectors, where the reverse current is three orders of magnetude smaller compared with irradiated detectors, the series noises dominates over the whole range of shaping times investigated (20-150ns). A signal degradation is observed for irradiated detectors. However, the signal ca be distinguished from noise, even after a fluence of about 1.2 x10(14) protons per cm2, at a temperature of 6ĂžC and with a shaping time tipical of rge LHC inter-bunch crossing time (20-30ns). The measurements of the signal as a function of voltage shows that irradiated detectors depleted at 50% of the full depletion voltage can still provide a measurable signal-to-noise ratio

    YBa2_2Cu3_3O7_7/La0.7_{0.7}Ca0.3_{0.3}MnO3_3 bilayers: Interface coupling and electric transport properties

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    Heteroepitaxially grown bilayers of ferromagnetic La0.7_{0.7}Ca0.3_{0.3}MnO3_3 (LCMO) on top of superconducting YBa2_2Cu3_3O7_7 (YBCO) thin films were investigated by focusing on electric transport properties as well as on magnetism and orbital occupation at the interface. Transport measurements on YBCO single layers and on YBCO/LCMO bilayers, with different YBCO thickness dYd_Y and constant LCMO thickness dL=50d_L=50\,nm, show a significant reduction of the superconducting transition temperature TcT_c only for dY<10d_Y<10\,nm,with only a slightly stronger TcT_c suppression in the bilayers, as compared to the single layers. X-ray magnetic circular dichroism (XMCD) measurements confirm recently published data of an induced magnetic moment on the interfacial Cu by the ferromagnetically ordered Mn ions, with antiparallel alignment between Cu and Mn moments. However, we observe a significantely larger Cu moment than previously reported, indicating stronger coupling between Cu and Mn at the interface. This in turn could result in an interface with lower transparency, and hence smaller spin diffusion length, that would explain our electric transport data, i.e.smaller TcT_c suppression. Moreover, linear dichroism measurements did not show any evidence for orbital reconstruction at the interface, indicating that a large change in orbital occupancies through hybridization is not necessary to induce a measurable ferromagnetic moment on the Cu atoms.Comment: 8 Figure

    Comparison of stimulation patterns for FES-cycling using measures of oxygen cost and stimulation cost

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    &lt;b&gt;Aim&lt;/b&gt;&lt;p&gt;&lt;/p&gt; The energy efficiency of FES-cycling in spinal cord injured subjects is very much lower than that of normal cycling, and efficiency is dependent upon the parameters of muscle stimulation. We investigated measures which can be used to evaluate the effect on cycling performance of changes in stimulation parameters, and which might therefore be used to optimise them. We aimed to determine whether oxygen cost and stimulation cost measurements are sensitive enough to allow discrimination between the efficacy of different activation ranges for stimulation of each muscle group during constant-power cycling. &lt;p&gt;&lt;/p&gt; &lt;b&gt;Methods&lt;/b&gt;&lt;p&gt;&lt;/p&gt; We employed a custom FES-cycling ergometer system, with accurate control of cadence and stimulated exercise workrate. Two sets of muscle activation angles (“stimulation patterns”), denoted “P1” and “P2”, were applied repeatedly (eight times each) during constant-power cycling, in a repeated measures design with a single paraplegic subject. Pulmonary oxygen uptake was measured in real time and used to determine the oxygen cost of the exercise. A new measure of stimulation cost of the exercise is proposed, which represents the total rate of stimulation charge applied to the stimulated muscle groups during cycling. A number of energy-efficiency measures were also estimated. &lt;p&gt;&lt;/p&gt; &lt;b&gt;Results&lt;/b&gt;&lt;p&gt;&lt;/p&gt; Average oxygen cost and stimulation cost of P1 were found to be significantly lower than those for P2 (paired &lt;i&gt;t&lt;/i&gt;-test, &lt;i&gt;p&lt;/i&gt; &lt; 0.05): oxygen costs were 0.56 ± 0.03 l min&lt;sup&gt;−1&lt;/sup&gt; and 0.61 ± 0.04 l min&lt;sup&gt;−1&lt;/sup&gt;(mean ± S.D.), respectively; stimulation costs were 74.91 ± 12.15 mC min&lt;sup&gt;−1&lt;/sup&gt; and 100.30 ± 14.78 mC min&lt;sup&gt;−1&lt;/sup&gt; (mean ± S.D.), respectively. Correspondingly, all efficiency estimates for P1 were greater than those for P2. &lt;p&gt;&lt;/p&gt; &lt;b&gt;Conclusion&lt;/b&gt;&lt;p&gt;&lt;/p&gt; Oxygen cost and stimulation cost measures both allow discrimination between the efficacy of different muscle activation patterns during constant-power FES-cycling. However, stimulation cost is more easily determined in real time, and responds more rapidly and with greatly improved signal-to-noise properties than the ventilatory oxygen uptake measurements required for estimation of oxygen cost. These measures may find utility in the adjustment of stimulation patterns for achievement of optimal cycling performance. &lt;p&gt;&lt;/p&gt

    A Measurement of Newton's Gravitational Constant

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    A precision measurement of the gravitational constant GG has been made using a beam balance. Special attention has been given to determining the calibration, the effect of a possible nonlinearity of the balance and the zero-point variation of the balance. The equipment, the measurements and the analysis are described in detail. The value obtained for G is 6.674252(109)(54) 10^{-11} m3 kg-1 s-2. The relative statistical and systematic uncertainties of this result are 16.3 10^{-6} and 8.1 10^{-6}, respectively.Comment: 26 pages, 20 figures, Accepted for publication by Phys. Rev.
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