Peste suína clássica: custo de um surto.

bitstream/item/58655/1/CUsersPiazzonDocuments190.pd

Phosphorus fractions in the vineyard soil of the Serra Gaúcha of Rio Grande do Sul, Brazil.

The study aimed to evaluate the accumulation of P fractions in a vineyard soil profile with successive applications of phosphate fertilizers. In January 2010 an area was selected of native forest and a vineyard at age 33 with a history of phosphate fertilizer application, in Bento Gonçalves, Rio Grande do Sul state. Soil samples were collected from 0-5, 5-10 and 10-20 cm layers, prepared and submitted to chemical fractionation of P. The excessive application of phosphate fertilizers during 33 years in the vineyard soil increased the levels of organic and inorganic P until the 20 cm layer in all P fractions. The highest levels of P in the vineyard soil were found mainly in the labile fractions extracted with anion exchange resin and NaHCO3, which indicates high nutrient availability to plants, but also indicates the potential of transfer of solution from soil to surface run-off or percolated through the soil profile, which represents greater potential for contamination of surface and subsurface waters

Avaliação da seletividade inicial de herbicidas para o tomateiro por meio da análise de fluorescência da clorofila.

Objetivou-se com este trabalho analisar a fluorescência da clorofila por meio da avaliação da taxa de transporte de eletrons em tomateiro como forma de avaliar a seletividade inicial de hervicidas aplicados em pré-transplate

Role of tipranavir in treatment of patients with multidrug-resistant HIV

The worldwide emergence of multidrug-resistant human immunodeficiency virus (HIV)-1 strains has the driven the development of new antiretroviral (ARV) agents. Over the past 5 years, HIV-entry and integrase inhibitor ARVs, as well as improved non-nucleoside reverse transcriptase inhibitors (NRTIs) and protease inhibitors (PIs), have become available for treatment. It is important to assess how these new ARVs might be most judiciously used, paying close attention to viral susceptibility patterns, pharmacodynamic parameters, and the likelihood that patients will adhere to their therapy. Herein we review published material in Medline, EMBASE, and ISI for each antiretroviral agent/classes currently approved and summarize the available data on their efficacy, safety, and pharmacologic parameters. We focus on the role of tipranavir, a recently approved nonpeptidic PI, for treating HIV-infected children, adolescents, and adults with a history of multidrug-resistant HIV

Phosphorus fractions in sandy soils of vineyards in Southern Brazil.

As aplicações de fósforo (P) em vinhedos podem causar o acúmulo desse nutriente no solo e maximizar seu potencial poluente. Este trabalho objetivou quantificar as frações de acumulação de P em solos arenosos cultivados com videiras na região Sul do Brasil. Para isso, amostras de solo foram coletadas nas camadas de 0-5, 6-10 e 11-20 cm em uma área de campo nativo e em dois vinhedos: um com 14 anos de cultivo (vinhedo 1) e outro com 30 anos (vinhedo 2), localizados no município de Santana do Livramento, Rio Grande do Sul (RS), Brasil. As amostras foram secas, moídas e submetidas ao fracionamento químico de P. Os resultados evidenciaram que os teores de P inorgânico aumentaram até 20 cm de profundidade, principalmente no vinhedo 2, em especial nas frações lábeis extraídas por resina de troca aniônica e por NaHCO3, na fração moderadamente lábil, extraída por NaOH 0,1 e 0,5 mol L-1, e na fração não lábil, extraída por HCl 1 mol L-1, representando potencial de eutroficação das águas. As aplicações de fertilizantes fosfatados na adubação de correção e de manutenção nos vinhedos com maior tempo de cultivo aumentaram os teores de P na fração orgânica extraída por NaHCO3 na camada de 0-5 cm, e na fração moderadamente lábil extraída por NaOH 0,1 mol L-1, até 20 cm de profundidade

Usher syndrome: An effective sequencing approach to establish a genetic and clinical diagnosis

12noUsher syndrome is an autosomal recessive disorder characterized by retinitis pigmentosa, sensorineural hearing loss and, in some cases, vestibular dysfunction. The disorder is clinically and genetically heterogeneous and, to date, mutations in 11 genes have been described. This finding makes difficult to get a precise molecular diagnosis and offer patients accurate genetic counselling. To overcome this problem and to increase our knowledge of the molecular basis of Usher syndrome, we designed a targeted resequencing custom panel. In a first validation step a series of 16 Italian patients with known molecular diagnosis were analysed and 31 out of 32 alleles were detected (97% of accuracy). After this step, 31 patients without a molecular diagnosis were enrolled in the study. Three out of them with an uncertain Usher diagnosis were excluded. One causative allele was detected in 24 out 28 patients (86%) while the presence of both causative alleles characterized 19 patients out 28 (68%). Sixteen novel and 27 known alleles were found in the following genes: USH2A (50%), MYO7A (7%), CDH23 (11%), PCDH15 (7%) and USH1G (2%). Overall, on the 44 patients the protocol was able to characterize 74 alleles out of 88 (84%). These results suggest that our panel is an effective approach for the genetic diagnosis of Usher syndrome leading to: 1) an accurate molecular diagnosis, 2) better genetic counselling, 3) more precise molecular epidemiology data fundamental for future interventional plans.partially_openembargoed_20160106Lenarduzzi, S.; Vozzi, D; Morgan, A.; Rubinato, E.; D'Eustacchio, A.; Osland, T.M.; Rossi, C.; Graziano, C.; Castorina, P.; Ambrosetti, U.; Morgutti, M.; Girotto, G.Lenarduzzi, Stefania; Vozzi, Diego; Morgan, Anna; Rubinato, Elisa; D'Eustacchio, A.; Osland, TERESA MARIA; Rossi, C.; Graziano, C.; Castorina, P.; Ambrosetti, U.; Morgutti, Marcello; Girotto, Giorgi

Experimental evaluation of the energy efficiency of a CO2 refrigerating plant working in transcritical conditions

[EN] This work presents the experimental evaluation of the energy efficiency and optimal gas-cooler pressures of a single-stage refrigerating plant working with carbon dioxide as refrigerant in transcritical conditions. The performance of the plant was tested at three different evaporating temperatures (-0.9, -10.1 and -18.1 degrees C), for three gas-cooler refrigerant outlet temperatures (31.2, 33.6 and 40.0 degrees C) at each evaporating temperature and in a wide range of gas-cooler pressures (74.4-104.7 bar). The experimental tests enabled us to calculate accurately the optimal gas-cooler pressures and compare them with the most commonly used relations to define this value in single-stage refrigerating cycles operating with carbon dioxide in transcritical conditions. Furthermore, an analysis of the reduction in energy efficiency produced in the plant if the optimum pressure is not well defined is also presented.The authors are indebted to Frost-Trol S.A. (www.frosttrol.com) and the Spanish Ministry of Education and Science (ENE2006-09972/CON) for the economical support given to the present work and for the Grant BES-2007-16820 linked to the Ministry projectCabello, R.; Sanchez, D.; Llopis, R.; Torrella Alcaraz, E. (2008). Experimental evaluation of the energy efficiency of a CO2 refrigerating plant working in transcritical conditions. Applied Thermal Engineering. 28(13):1596-1604. https://doi.org/10.1016/j.applthermaleng.2007.10.026S15961604281

Optimization of a high work function solution processed vanadium oxide hole-extracting layer for small molecule and polymer organic photovoltaic cells

We report a method of fabricating a high work function, solution processable vanadium oxide (V2Ox(sol)) hole-extracting layer. The atmospheric processing conditions of film preparation have a critical influence on the electronic structure and stoichiometry of the V2Ox(sol), with a direct impact on organic photovoltaic (OPV) cell performance. Combined Kelvin probe (KP) and ultraviolet photoemission spectroscopy (UPS) measurements reveal a high work function, n-type character for the thin films, analogous to previously reported thermally evaporated transition metal oxides. Additional states within the band gap of V2Ox(sol) are observed in the UPS spectra and are demonstrated using X-ray photoelectron spectroscopy (XPS) to be due to the substoichiometric nature of V2Ox(sol). The optimized V2Ox(sol) layer performance is compared directly to bare indium–tin oxide (ITO), poly(ethyleneoxythiophene):poly(styrenesulfonate) (PEDOT:PSS), and thermally evaporated molybdenum oxide (MoOx) interfaces in both small molecule/fullerene and polymer/fullerene structures. OPV cells incorporating V2Ox(sol) are reported to achieve favorable initial cell performance and cell stability attributes