24 research outputs found

    Major variations in malaria exposure of travellers in rural areas: an entomological cohort study in western CĂŽte d'Ivoire

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    <p>Abstract</p> <p>Background</p> <p>Malaria remains a major threat, to both travellers and military personnel deployed to endemic areas. The recommendations for travellers given by the World Health Organization is based on the incidence of malaria in an area and do not take the degree of exposure into account. The aim of this article is to evaluate the exposure of travellers by entomologic methods, which are the commonly used measures of the intensity of malaria transmission.</p> <p>Methods</p> <p>From February 2004 to June 2004, five groups of 30 military personnel were stationed in up to 10 sites in western CĂŽte d'Ivoire, from one week to several months. Adult mosquitoes were collected by human landing catches at each site during the five months and the level of exposure to malaria transmission of each group was estimated.</p> <p>Results</p> <p>The level of transmission varied from one site to another one from less than one to approximately more than 100 infective bites per month. In the majority of sites, at least two anopheline species were involved in transmission. The cumulative EIR over the study period varied according to the groups from 29 infected bites per person/per mission to 324.</p> <p>Conclusion</p> <p>The level of malaria transmission and malaria risk varies widely (varying by a factor of eleven) between groups of travellers travelling in the same region and at the same time. Physicians involved in travel medicine or supporting expatriated populations or refugees should consider this heterogeneity and emphasize the importance of combining appropriate measures, such as chemoprophylaxis and protective measures against mosquitoes.</p

    Chaos in Magnetic Nanocontact Vortex Oscillators

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    International audienceWe present an experimental study of spin-torque driven vortex self-oscillations in magnetic nanocontacts. We find that above a certain threshold in applied currents, the vortex gyration around the nanocontact is modulated by relaxation oscillations, which involve periodic reversals of the vortex core. This modulation leads to the appearance of commensurate but also more interestingly here, incommensurate states, which are characterized by devil's staircases in the modulation frequency. We use frequency-and time-domain measurements together with advanced time-series analyses to provide experimental evidence of chaos in incommensurate states of vortex oscillations, in agreement with theoretical predictions. Chaos describes a deterministic nonlinear dynamical process that is exponentially sensitive to initial conditions. In the context of physical systems such as micro-electronic or photonic devices, chaotic behavior has been studied for different possible applications in information technologies [1, 2], where the underlying premise is that the complexity of a chaotic signal can be harnessed to compute or process information. For example, the high information entropy content of a chaotic signal can be used for random number generation at GHz rates and beyond [3-6], its symbolic dynamics can be used to encode information [7-10], and the possibly large fractal dimension combined with synchronization capabilities makes it an ideal source for secure communications at the physical level [11, 12]. In this context, nanoscale spintronic devices such as spin-torque nano-oscillators [13-16] are promising for chaos-based applications for a number of reasons. First, magnetization dynamics is inherently nonlinear as a result of magnetocrystalline anisotropies, dipolar interactions , and certain nonconservative processes. Second, spin-dependent transport effects, such as spin transfer torques [17], which allow magnetization dynamics to be driven by electrical currents, and magnetoresistance, which allows such dynamics to be detected electrically, offer promising avenues for integration into micro-and nanoelectronics. In these systems, chaos can appear as a result of periodic driving [18, 19], as delayed-feedback effects [20], in the dynamics of coupled vortices [21], and during magnetization reversal [22]. The nanocontact vortex oscillator [23-30] represents an intriguing example, where different commensurate and incommensurate states appear due to competing self-oscillations [27]. The primary oscillation is driven by spin torques and involves self-sustained vortex gyration around the nanocontact [24], which is accompanied by relaxation oscillations in the form of periodic core reversal above a threshold current. Commensurate states represent self-phase locking between these two modes, where the ratio of the two frequencies is rational, while for incommensurate phases this ratio is irrational. Simulations have suggested that incommensurate phases lead to a chaotic time series, but this had not been observed directly in our earlier experiments. In this Letter, we present experimental observations of such incommensurate states in a nanocontact vortex oscillator. By using frequency-and time-resolved measurements together with advanced time series analysis of the magnetization dynamics, we show first signatures in the power spectra and autocorrelation function that are consistent with the chaotic behavior predicted in simulations. We further support these findings using the technique of titration of chaos with added noise [31], which reveals a strong level of nonlinearity only in the incom-mensurate states, consistent with the presence of chaos. An illustration of the nanocontact system is presented in Fig. 1(a). The spin valve is an extended multilay-ered film with the composition SiO 2 /Cu (40)/Co (20)/Cu (10)/Ni 81 Fe 19 (20)/Au (6)/photoresist (50)/Au (top contact), where the figures in parentheses are layer thicknesses in nm. The multilayer was grown at room temperature by dc magnetron sputtering in an argon atmosphere with a residual pressure of 6.4 × 10 −8 mbar. The film was subjected to stabilization annealing during the fabrication process at 170 ‱ C for 1 minute. The film magnetic properties were determined prior to patterning using vector network analyzer ferromagnetic resonance. The NiFe layer has the expected soft properties, including a coercivity of 1 mT, a saturation magnetization ” 0 M s = (1.053 ± 0.003) T, a spectroscopic splitting factor of g = 2.111 ± 0.003, and a Gilbert damping constant of α = (7 ± 1) × 10 −3. The Co layer is also relatively soft arXiv:1903.00921v2 [cond-mat.mes-hall

    3q27.3 microdeletional syndrome:a recognisable clinical entity associating dysmorphic features, marfanoid habitus, intellectual disability and psychosis with mood disorder

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    Background: Since the advent of array-CGH, numerous new microdeletional syndromes have been delineated while others remain to be described. Although 3q29 subtelomeric deletion is a well-described syndrome, there is no report on 3q interstitial deletions. Methods: We report for the first time seven patients with interstitial deletions at the 3q27.3q28 locus gathered through the Decipher database, and suggest this locus as a new microdeletional syndrome. Results: The patients shared a recognisable facial dysmorphism and marfanoid habitus, associated with psychosis and mild to severe intellectual disability (ID). Most of the patients had no delay in gross psychomotor acquisition, but had severe impaired communicative and adaptive skills. Two small regions of overlap were defined. The first one, located on the 3q27.3 locus and common to all patients, was associated with psychotic troubles and mood disorders as well as recognisable facial dysmorphism. This region comprised several candidate genes including SST, considered a candidate for the neuropsychiatric findings because of its implication in interneuronal migration and differentiation processes. A familial case with a smaller deletion allowed us to define a second region of overlap at the 3q27.3q28 locus for marfanoid habitus and severe ID. Indeed, the common morphological findings in the first four patients included skeletal features from the marfanoid spectrum: scoliosis (4/4), long and thin habitus with leanness (average Body Mass Index of 15 (18.5<N<25)) (4/4), arachnodactyly (3/4) and pectus excavatum (2/4)). This phenotype could be explained by the deletion of the AHSG gene, which encodes a secreted protein implicated in bone maturation and the TGFb signalling pathway. Conclusions: We report on a new microdeletional syndrome that associates with a recognisable facial dysmorphism and marfanoid habitus including scoliosis, neuropsychiatric disorders of the psychotic spectrum and moderate to severe ID

    High Level Architecture (HLA) : release 3.0 : AIOTI WG03 - loT Standardisation

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    In the context of AIOTI (Alliance for Internet of Things Innovation) WG03 and by following the evolution on IoT architectural aspects and available specifications, AIOTI WG03 has developed a High Level Architecture (HLA) for IoT that should be applicable to AIOTI Large Scale Pilots. The HLA takes into account existing SDOs and alliances architecture specification

    Lifetime measurement for the 21+ state in Sm 140 and the onset of collectivity in neutron-deficient Sm isotopes

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    Background: The chain of Sm isotopes exhibits a wide range of nuclear shapes and collective behavior. While the onset of deformation for N > 82 has been well studied both experimentally and theoretically, fundamental data is lacking for some Sm isotopes with N < 82. Purpose: Electromagnetic transition rates represent a sensitive test of theoretical nuclear structure models. Lifetime measurements are furthermore complementary to Coulomb excitation experiments, and the two methods together can give access to spectroscopic quadrupole moments. Method: The lifetime of the 2+ 1 state in 140Sm was measured with the recoil-distance Doppler shift technique using the reaction 124Te( 20Ne, 4n) 140Sm at 82 MeV. Theoretical calculations were performed based on a mapped collective Hamiltonian in five quadrupole coordinates (5DCH) and the Gogny D1S interaction. Results: The lifetime of the 2+ 1 state in 140Sm was found to be 9.1(6) ps, corresponding to aB(E2; 2+ 1 → 0+ 1 ) value of 51(4) Weisskopf units. The theoretical calculations are in very good agreement with the experimental result. Conclusions: The B(E2; 2+ 1 → 0+ 1 ) value for 140Sm fits smoothly into the systematic trend for the chain of Sm isotopes. The new beyond-mean field calculations are able to correctly describe the onset of collectivity in the Sm isotopes below the N = 82 shell closure for the first time
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