Transoesophageal detection of heart graft rejection by electrical impedance: using Finite Element Method simulations

Previous studies have shown that it is possible to evaluate heart graft rejection level using a bioimpedance technique by means of an intracavitary catheter. However, this technique does not present relevant advantages compared to the gold standard for the detection of a heart rejection, which is the biopsy of the endomyocardial tissue. We propose to use a less invasive technique that consists in the use of a transoesophageal catheter and two standard ECG electrodes on the thorax. The aim of this work is to evaluate different parameters affecting the impedance measurement, including: sensitivity to electrical conductivity and permittivity of different organs in the thorax, lung edema and pleural water. From these results, we deduce the best estimator for cardiac rejection detection, and we obtain the tools to identify possible cases of false positive of heart rejection due to other factors. To achieve these objectives we have created a thoracic model and we have simulated, with a FEM program, different situations at the frequencies of 13, 30, 100, 300 and 1000 kHz. Our simulation demonstrates that the phase, at 100 and 300 kHz, has the higher sensitivity to changes in the electrical parameters of the heart muscle.Peer ReviewedPostprint (author’s final draft

First observation of 54Zn and its decay by two-proton emission

The nucleus 54Zn has been observed for the first time in an experiment at the SISSI/LISE3 facility of GANIL in the quasi-fragmentation of a 58Ni beam at 74.5 MeV/nucleon in a natNi target. The fragments were analysed by means of the ALPHA-LISE3 separator and implanted in a silicon-strip detector where correlations in space and time between implantation and subsequent decay events allowed us to generate almost background free decay spectra for about 25 different nuclei at the same time. Eight 54Zn implantation events were observed. From the correlated decay events, the half-life of 54Zn is determined to be 3.2 +1.8/-0.8 ms. Seven of the eight implantations are followed by two-proton emission with a decay energy of 1.48(2) MeV. The decay energy and the partial half-life are compared to model predictions and allow for a test of these two-proton decay models.Comment: 4 pages, 4 figures, accepted for publication in PR

First observation of 55,56Zn

In an experiment at the SISSI/LISE3 facility of GANIL, the most proton-rich zinc isotopes 55,56Zn have been observed for the first time. The experiment was performed using a high-intensity 58Ni beam at 74.5 MeV/nucleon impinging on a nickel target. The identification of 55,56Zn opens the way to 54Zn, a good candidate for two-proton radioactivity according to theoretical predictions.Comment: 2 pages, 1 figure, accepted for publication in Eur. Phys. J.

Decay of proton-rich nuclei between 39Ti and 49Ni

Decay studies of very neutron-deficient nuclei ranging from 39Ti to 49Ni have been performed during a projectile fragmentation experiment at the GANIL/LISE3 separator. For all nuclei studied in this work, 39,40Ti, 42,43Cr, 46Mn, 45,46,47Fe and 49Ni, half-lives and decay spectra have been measured. In a few cases, gamma coincidence measurements helped to successfully identify the initial and final states of transitions. In these cases, partial decay scheme are proposed. For the most exotic isotopes, 39Ti, 42Cr, 45Fe and 49Ni, which are candidates for two-proton radioactivity from the ground state, no clear evidence of this process is seen in our spectra and we conclude rather on a delayed particle decay.Comment: 12 pages, 15 figures, submitted for publication in Eur. Phys. J.

First direct observation of two protons in the decay of 45^{45}Fe with a TPC

The decay of the ground-state two-proton emitter 45Fe was studied with a time-projection chamber and the emission of two protons was unambiguously identified. The total decay energy and the half-life measured in this work agree with the results from previous experiments. The present result constitutes the first direct observation of the individual protons in the two-proton decay of a long-lived ground-state emitter. In parallel, we identified for the first time directly two-proton emission from 43Cr, a known beta-delayed two-proton emitter. The technique developped in the present work opens the way to a detailed study of the mechanism of ground-state as well as beta-delayed two-proton radioactivity.Comment: 4 pages, 5 figure

Monosegment ALPPS hepatectomy preserving segment 4 for colorectal liver metastases : literature review and our experience

Peer reviewedPublisher PD

Precision measurement of the half-life and the decay branches of 62Ga

In an experiment performed at the Accelerator Laboratory of the University of Jyvaskyla, the beta-decay half-life of 62Ga has been studied with high precision using the IGISOL technique. A half-life of T1/2 = 116.09(17)ms was measured. Using beta-gamma coincidences, the gamma intensity of the 954keV transition and an upper limit of the beta-decay feeding of the 0+_2 state have been extracted. The present experimental results are compared to previous measurements and their impact on our understanding of the weak interaction is discussed.Comment: 7 pages, 7 figures, submitted to EPJ

Beta-decay branching ratios of 62Ga

Beta-decay branching ratios of 62Ga have been measured at the IGISOL facility of the Accelerator Laboratory of the University of Jyvaskyla. 62Ga is one of the heavier Tz = 0, 0+ -> 0+ beta-emitting nuclides used to determine the vector coupling constant of the weak interaction and the Vud quark-mixing matrix element. For part of the experimental studies presented here, the JYFLTRAP facility has been employed to prepare isotopically pure beams of 62Ga. The branching ratio obtained, BR= 99.893(24)%, for the super-allowed branch is in agreement with previous measurements and allows to determine the ft value and the universal Ft value for the super-allowed beta decay of 62Ga