Severe and fatal measles-associated pneumonia during an outbreak in Italy: data from the heart of the epidemic

Introduction: Measles is a contagious disease that re-emerged among young adults as a consequence of suboptimal vaccination coverage. Since in the pre-vaccination era measles affected mainly children, little is known about measles-associated respiratory complications in adults. The aim of this study was to describe clinical and radiological findings in adults affected by measles who developed respiratory complications during a recent measles outbreak. Material and methods: In this retrospective chart review-based study we analyzed data from patients admitted for measles from January to June 2018 to a large tertiary care hospital, in one of the main cities in the south of Italy. This city has been the country’s heart of the epidemic with a high morbidity and mortality rate. Results: Among 177 patients (mean age 26 ± 9 years), only 2 were vaccinated. Thirty patients (16.9%) had signs of pneumonia on chest radiography. Computed tomography scan showed the following abnormalities: centrilobular nodules (63%), ground-glass attenuation (63%), air-space consolidation (36%), pleural effusion (16%) and pneumothorax (10%). Five patients developed severe lung injury and hypoxemia requiring admission to Intensive Care Unit. Two young unvaccinated women with no past medical history died from acute respiratory failure. The death was sudden and unpredictable. Conclusions: Measles-associated pneumonia in unvaccinated young adults can cause severe respiratory impairment and death. Our findings support the need for a mandatory vaccination policy

Daylighting Contribution for Energy Saving in a Historical Building

AbstractThe purpose of this study is assessing the reliability of the software DIALux 4.12 for daylighting design, comparing experimental data with simulation results; the comparison was performed for an office.The daylight illuminance distribution inside the room, the external zenith luminance and the external horizontal diffuse illuminance were measured during the weeks from January 19th to February 20th; the data gathered were further reduced to match conditions related to the CIE sky type #12 (CIE Standard Clear Sky, low luminance turbidity) and finally the comparison was carried in terms of daylight illuminance distribution and relative percentage error

Low-cost smart solutions for daylight and electric lighting integration in historical buildings

Research have shown that the correct integration of daylight and electric lighting reduces the energy use in buildings, while improving visual comfort. Smart shading systems, especially those electrically controlled, play an important role to control solar radiation. Similarly, smart and dimmable/tunable lighting can help to adjust the artificial light to the real users' needs. This paper presents preliminary results of an ongoing living lab study investigating how artificial lighting systems can be integrated with shading systems, placing human comfort at the heart of the study and yet saving energy. A manually controlled, commercial and low-cost smart system integrating two motorized shading devices and six dimmable LED luminaires with a different selection of CCT were installed in a private office in a historical building. Indoor and outdoor lighting conditions and energy consumption associated to the lighting system are constantly monitored to assess how the people use shading and lighting upon varying the boundary conditions.. Preliminary results highlight that users prefer to maximise daylight on the work plane as well as they generally use both shading and electric lighting systems in response to boundary conditions that cause serious discomfort

Energy Performances of Tensile Material in Building Renovation in the Nordic Region

Tensile materials are increasingly used in the building envelope as second-skin systems, despite a lack of investigation on their effects. In this work, a second-skin system integrating a tensile material as an outer layer has been adopted in the retrofit analysis of two of the most common building typologies in the Norwegian context. The simulations were carried out by implementing a custom control logic for the system, considering the outdoor air temperature and the global vertical irradiation on the façades. The proposed retrofit solution allowed for a primary energy saving of about 35%.publishedVersio

DYNAMIC SIMULATION OF A SOLAR HEATING AND COOLING SYSTEM INCLUDING A SEASONAL STORAGE SERVING A SMALL ITALIAN RESIDENTIAL DISTRICT

A centralized solar hybrid heating and cooling system satisfying the thermal, cooling and sanitary water demands of a typical Italian small district composed of six residential buildings situated in Naples (southern Italy) is modelled, simulated and analysed through the software TRNSYS over a period of 5 years. The plant is based on the operation of solar thermal collectors coupled with seasonal borehole storage; the solar field is also composed of photovoltaic solar panels connected with electric energy storage. An adsorption chiller powered by solar energy is adopted for cooling purposes, while a condensing boiler is used as an auxiliary unit. The performance of the proposed system has been assessed from energy, environmental and economic points of view and contrasted with the operation of a typical Italian heating and cooling plant, highlighting the following main results: saving of primary energy consumption up to 40.2%; (decrease of equivalent CO2 emissions up to 38.4%; reduction of operating costs up to 40.1%; and simple pay-back period of about 20 years

Thermal Performance of an Electric-Driven Smart Window: Experiments in a Full-Scale Test Room and Simulation Model

This paper reports the results of experimental tests and numerical simulations aimed at evaluating the performance of an electric-driven smart window with respect to solar control in buildings. The experimental performances of the electric-driven smart window were evaluated using a south oriented full scale experimental facility designed and realized. The tests were carried out during the summer under real sky conditions upon varying the state of the electricdriven smart window (clear and milky). In the first part of the paper, the experimental results are discussed in terms of surface temperature of glazings as well as indoor air temperature in order to highlight the potential benefits on thermal comfort associated to the application of electric-driven smart windows. In the second part of this paper, the experimental data are compared to the numerical results generated through a simulation model of the electric-driven smart window in order to assess its reliability under different operating scenarios. Finally, the simulation model is used to quantify the potential cooling load reduction deriving from the integration of electric-driven smart windows in an office façade located in Naples (Italy)

Chapter Il Jardines El Capricho a Madrid. Dall’analisi delle fonti d’archivio al rilievo fotogrammetrico

The 43rd UID conference, held in Genova, takes up the theme of ‘Dialogues’ as practice and debate on many fundamental topics in our social life, especially in these complex and not yet resolved times. The city of Genova offers the opportunity to ponder on the value of comparison and on the possibilities for the community, naturally focused on the aspects that concern us, as professors, researchers, disseminators of knowledge, or on all the possibile meanings of the discipline of representation and its dialogue with ‘others’, which we have broadly catalogued in three macro areas: History, Semiotics, Science / Technology. Therefore, “dialogue” as a profitable exchange based on a common language, without which it is impossible to comprehend and understand one another; and the graphic sign that connotes the conference is the precise transcription of this concept: the title ‘translated’ into signs, derived from the visual alphabet designed for the visual identity of the UID since 2017. There are many topics which refer to three macro sessions: - Witnessing (signs and history) - Communicating (signs and semiotics) - Experimenting (signs and sciences) Thanks to the different points of view, an exceptional resource of our disciplinary area, we want to try to outline the prevailing theoretical-operational synergies, the collaborative lines of an instrumental nature, the recent updates of the repertoires of images that attest and nourish the relations among representation, history, semiotics, sciences

Biomechanical podiatric evaluation in an Italian cohort of patients with Systemic Sclerosis: a pilot study

OBJECTIVE: Foot problems are often present in Systemic Sclerosis (SSc) patients, however studies regarding podiatric problems related to SSc are lacking and there are no data evaluating the foot biomechanical changes. The aim of the present pilot study was to evaluate podiatric problems in an Italian cohort of SSc patients by assessing received podiatric services, foot pain and disability and biomechanical foot deformity. MATERIAL AND METHODS: 25 consecutive SSc patients were enrolled from the Division of Rheumatology, University of Florence. All SSc patients were assessed by: Standards of Care for People with Foot Musculoskeletal Health problems: Audit Tool, Foot Function Index (FFI), Weight and non-weight bearing foot joint assessment, (Foot Posture Index (FPI) and Gait Cycle), Health Assessment Questionnaire (HAQ) and Medical Outcomes Survey Short Form 36 (SF-36). RESULTS: Audit Tool - Only 7 (28%) out of the 25 patients with SSc had a specific podiatric assessment and treatment: no patient received a foot health assessment within the first 6 months of disease diagnosis and no patient received information about foot involvement. 1 patient (4%) received foot assessment every year; 1 patient (4%) received specific information about the disease and 5 patients (20%) received information about the benefits of using adapted footwear and insoles. FFI - Values of pain, disability and activity limitations, reported in FFI, are 4.7±5.1, 5.1±3.2 and 3.2±3.1 (M±DS), respectively. Non-weight bearing foot joint assessment shows a rearfoot varus deformity in 64% of patients, forefoot varus deformity in 42% and 6% forefoot valgus deformity. Weight bearing foot joint assessment, through FPI shows a pronated foot 20% of patients with and 34% with highly pronated overall foot posture. Gait analysis shows that 64% of patients has a contact of the calcaneus in invertion while 36% in eversion. In the midstance, 78% have the foot in pronation and 22% in supination, while in propulsion 12% presents a takeoff of the foot in supination and 88% in the pronation. HAQ result is 1.13±0.80, SFI and SMI scales of SF-36 have scores of 32.38±10.65 and 38.67±11.40, respectively. CONCLUSION: Our results shows that podiatric problems in SSc patients are common, serious but foot assessment and health care are inadequate. Thus, foot health information should be improved in order to better empower patients to self-manage low risk problems and help identify high-risk problems, which require specialist care