Maturity Models in Industrial Internet: a Review

The introduction of assembly lines in industrial plants marked the beginning of the third industrial revolution. The support of information technology has enabled continuous progresses, up to the digitalisation of the processes. In this context, the further innovation characterised by the introduction of Cyber-Physical Systems and other enabling technologies has allowed the fourth industrial revolution. Proposed by the German government, Industry 4.0 appealed to both researchers and practitioners. Since the appearance of the term Industry 4.0, the linked-term Industrial Internet has been introduced to indicate the technology stack and knowledge management required by Industry 4.0. Industrial Internet makes a factory smart by applying advanced information and communication systems and future-oriented technologies, as well as new principles of knowledge management. Undeniably, such a system introduces greater complexity in terms of technologies, knowledge and socio-cultural aspects. Companies are often unprepared to deal with innovation issues, because they lack knowledge and competences and they are not culturally prepared for the relative novelties, but especially because they lack the necessary technological pre-requisites to develop the appropriate technology stack. From this perspective, different models of maturity have been developed, both in academic and technical environments, to support companies in understanding their position within the paradigm of the Industrial Internet. Starting from a quantitative review of the maturity models designed in the general literature, this article develops a qualitative review of the models applied in Industry 4.0, characterising all relevant models and proposing future perspectives to improve existing models and develop new ones

Prevalence of Nonalcoholic Fatty Liver Disease and Its Association With Cardiovascular Disease Among Type 2 Diabetic Patients

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The impact of RFID technologies on inventory accuracy in the apparel retailing: Evidence from the field

In this paper, we assess the level of inventory accuracy that can be reached by adopting radio frequency identification (RFID) technology for inventory count operations in the fashion retailing. Thanks to an in-field implementation, we carried out two series of RFID inventory counts and compared the resulting accuracy level with that obtained exploiting the traditional barcode (BC) technology, so as to highlight the main pros and cons of the RFID adoption. As a general conclusion, the findings from the experimental campaigns and the analyses carried out suggest that RFID inventory counts are more reliable thanBCones. Moreover, under several circumstances, RFID allows detecting out-of-stock situations that are not evident when using either the BC technology or the inventory data stored in the company\u2019 information system. From those findings, a trend of the inventory accuracy as a function of the time required for RFID inventory counts is empirically derived. Such a trend can be exploited in practical cases to estimate the accuracy level achievable with inventory counts depending on the time dedicated to those activities

Optimizing Retrieving Performance of an Automated Warehouse for Unconventional Stock Keeping Units

In recent years, the diffusion of automated warehouses in different industrial sectors has fostered the design of more complex automated storages and handling solutions. These circumstances, from a technological point of view, have led to the development of automated warehouses that are very different from the classic pallet Automated Storage and Retrieval Systems (AS/RS), both in terms of design and operating logic. A context in which these solutions have spread is the steel sector. Warehouses with innovative layouts and operating logics have been designed to move metal bundles of different sizes, weights and quality levels, instead of standard, interchangeable stock keeping units. Moreover, picking is often not allowed in these warehouses, due to the configuration of the loading units. In this work we propose a meta-heuristic algorithm based on the Simulated Annealing (SA) procedure, which aims to optimize performance during the retrieving phase of an automated warehouse for metal bundles. The algorithm translates the customers’ requests, expressed in terms of item code, quality and weight into a list of jobs. The goal is to optimize the retrieving performance, measured in missions per hour, minimizing the deviations in quality and weight between customer request and the material retrieved. For the validation, a simulation model of an existing warehouse has been created and the performance of the algorithm tested on the simulation model has been compared with the current performance of the warehouse

Rapid Assessment of Landslide Dynamics by UAV-RTK Repeated Surveys Using Ground Targets: The Ca’ Lita Landslide (Northern Apennines, Italy)

The combined use of Uncrewed Aerial Vehicles (UAVs) with an integrated Real Time Kinematic (RTK) Global Navigation Satellite System (GNSS) module and an external GNSS base station allows photogrammetric surveys with centimeter accuracy to be obtained without the use of ground control points. This greatly reduces acquisition and processing time, making it possible to perform rapid monitoring of landslides by installing permanent and clearly recognizable optical targets on the ground. In this contribution, we show the results obtained in the Ca’ Lita landslide (Northern Apennines, Italy) by performing multi-temporal RTK-aided UAV surveys. The landslide is a large-scale roto-translational rockslide evolving downslope into an earthslide–earthflow. The test area extends 60 × 103 m2 in the upper track zone, which has recently experienced two major reactivations in May 2022 and March 2023. A catastrophic event took place in May 2023, but it goes beyond the purpose of the present study. A total of eight UAV surveys were carried out from October 2020 to March 2023. A total of eight targets were installed transversally to the movement direction. The results, in the active portion of the landslide, show that between October 2020 and March 2023, the planimetric displacement of targets ranged from 0.09 m (in the lateral zone) to 71.61 m (in the central zone). The vertical displacement values ranged from −2.05 to 5.94 m, respectively. The estimated positioning errors are 0.01 (planimetric) and 0.03 m (vertical). The validation, performed by using data from a permanent GNSS receiver, shows maximum differences of 0.18 m (planimetric) and 0.21 m (vertical). These results, together with the rapidity of image acquisition and data processing, highlight the advantages of using this rapid method to follow the evolution of relatively rapid landslides such as the Ca’ Lita landslide

Validation of the peroneal nerve test to diagnose critical illness polyneuropathy and myopathy in the intensive care unit: the multicentre Italian CRIMYNE-2 diagnostic accuracy study

Objectives: To evaluate the accuracy of the peroneal nerve test (PENT) in the diagnosis of critical illness polyneuropathy (CIP) and myopathy (CIM) in the intensive care unit (ICU). We hypothesised that abnormal reduction of peroneal compound muscle action potential (CMAP) amplitude predicts CIP/CIM diagnosed using a complete nerve conduction study and electromyography (NCS-EMG) as a reference diagnostic standard. Design: prospective observational study. Setting: Nine Italian ICUs. Patients: One-hundred and twenty-one adult (≥18 years) neurologic (106) and non-neurologic (15) critically ill patients with an ICU stay of at least 3 days. Interventions: None. Measurements and main results: Patients underwent PENT and NCS-EMG testing on the same day conducted by two independent clinicians who were blind to the results of the other test. Cases were considered as true negative if both NCS-EMG and PENT measurements were normal. Cases were considered as true positive if the PENT result was abnormal and NCS-EMG showed symmetric abnormal findings, independently from the specific diagnosis by NCS-EMG (CIP, CIM, or combined CIP and CIM). All data were centrally reviewed and diagnoses were evaluated for consistency with predefined electrophysiological diagnostic criteria for CIP/CIM. During the study period, 342 patients were evaluated, 124 (36.3%) were enrolled and 121 individuals with no protocol violation were studied. Sensitivity and specificity of PENT were 100% (95% CI 96.1-100.0) and 85.2% (95% CI 66.3-95.8). Of 23 patients with normal results, all presented normal values on both tests with no false negative results. Of 97 patients with abnormal results, 93 had abnormal values on both tests (true positive), whereas four with abnormal findings with PENT had only single peroneal nerve neuropathy at complete NCS-EMG (false positive). Conclusions: PENT has 100% sensitivity and high specificity, and can be used as a screening test to diagnose CIP/CIM in the ICU

Early pharmacological interventions for preventing post-traumatic stress disorder (PTSD): a network meta-analysis

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To assess the efficacy and acceptability of pharmacological interventions for preventing post‐traumatic stress disorder (PTSD) in adults exposed to a traumatic event and to generate a clinically useful ranking of pharmacological interventions according to their efficacy and acceptability by performing a network meta‐analysis

Draft Whole-Genome Sequence of the Biocontrol Agent Trichoderma harzianum T6776

Trichoderma harzianum T6776 is a promising beneficial isolate whose effects consist of growth promotion, positive response of photosynthetic activity, hormonal signaling, and carbon partitioning in tomato, coupled with biocontrol of plant pathogens. Here, we present the first genome assembly of T6776, providing a useful platform for the scientific community

Clinical trajectories of individuals with severe mental illness continuing and discontinuing long-acting antipsychotics: a one-year mirror-image analysis from the STAR Network Depot study

Evidence on long-acting antipsychotics (LAIs) in unselected populations with severe mental illness is scant. In this mirror-image study, we compared multiple clinical outcomes 1 year before and after a first LAI prescription in adults with severe mental illness, describing clinical trajectories of LAI continuers and discontinuers. We compared LAI continuers and discontinuers through Mann–Whitney U test, Kaplan–Meier survival curves, regression for interval-censored data, and a maximum-likelihood mixed-model with individual random-effect and time as predictor. Of the 261 participants analyzed, 71.3% had schizophrenia-spectrum disorders, and 29.5% discontinued the LAI before 1 year. At baseline, LAI discontinuers had a shorter illness duration, lower attitude and adherence scores. The mirror-image analysis showed reduced hospital admissions only for LAI continuers. Over time, continuers spent less days hospitalized, but had more adverse events and more antipsychotics prescribed, with higher overall doses. In conclusion, this study shows that LAIs might be beneficial in unselected patient populations, provided that adherence is maintained. LAI continuers spent less time hospitalized, but received more antipsychotics and suffered from more cumulative adverse events over time. Therefore, the choice of initiating and maintaining a LAI should be carefully weighed on a case-by-case basis

Clinical trajectories of individuals with severe mental illness continuing and discontinuing long-acting antipsychotics: a one-year mirror-image analysis from the STAR Network Depot study

Evidence on long-acting antipsychotics (LAIs) in unselected populations with severe mental illness is scant. In this mirror-image study, we compared multiple clinical outcomes 1 year before and after a first LAI prescription in adults with severe mental illness, describing clinical trajectories of LAI continuers and discontinuers. We compared LAI continuers and discontinuers through Mann-Whitney U test, Kaplan-Meier survival curves, regression for interval-censored data, and a maximum-likelihood mixed-model with individual random-effect and time as predictor. Of the 261 participants analyzed, 71.3% had schizophrenia-spectrum disorders, and 29.5% discontinued the LAI before 1 year. At baseline, LAI discontinuers had a shorter illness duration, lower attitude and adherence scores. The mirror-image analysis showed reduced hospital admissions only for LAI continuers. Over time, continuers spent less days hospitalized, but had more adverse events and more antipsychotics prescribed, with higher overall doses. In conclusion, this study shows that LAIs might be beneficial in unselected patient populations, provided that adherence is maintained. LAI continuers spent less time hospitalized, but received more antipsychotics and suffered from more cumulative adverse events over time. Therefore, the choice of initiating and maintaining a LAI should be carefully weighed on a case-by-case basis