Bulk-suppressed and surface-sensitive Raman scattering by transferable plasmonic membranes with irregular slot-shaped nanopores

Abstract Raman spectroscopy enables the non-destructive characterization of chemical composition, crystallinity, defects, or strain in countless materials. However, the Raman response of surfaces or thin films is often weak and obscured by dominant bulk signals. Here we overcome this limitation by placing a transferable porous gold membrane, (PAuM) on the surface of interest. Slot-shaped nanopores in the membrane act as plasmonic antennas and enhance the Raman response of the surface or thin film underneath. Simultaneously, the PAuM suppresses the penetration of the excitation laser into the bulk, efficiently blocking its Raman signal. Using graphene as a model surface, we show that this method increases the surface-to-bulk Raman signal ratio by three orders of magnitude. We find that 90% of the Raman enhancement occurs within the top 2.5 nm of the material, demonstrating truly surface-sensitive Raman scattering. To validate our approach, we quantify the strain in a 12.5 nm thin Silicon film and analyze the surface of a LaNiO3 thin film. We observe a Raman mode splitting for the LaNiO3 surface-layer, which is spectroscopic evidence that the surface structure differs from the bulk. These results validate that PAuM gives direct access to Raman signatures of thin films and surfaces

Teen mothers who are daughters of teen mothers: Psychological intergenerational dimensions of early motherhood

Introduction: Researchers have shown that being a daughter of a teenage mother is a risk factor regarding the possibility of having early, unprotected sexual intercourse and of falling pregnant. The experiences of young mothers in such situations and the aspects of intergenerational transmission in the mother–daughter relationship have not been well investigated. Objectives: This study analyses the experience of motherhood in young mothers (18–20 years at the time of the interview/15–16 at the time of their pregnancy) who are daughters of teen mothers themselves from the psychodynamic perspective of intergenerational transmission. Methods: Six young mothers from Southern Italy were selected and interviewed. A semi-structured interview was used to explore the early experience of pregnancy and motherhood and their relationship with their own mothers. The interviews were analysed through Interpretative Phenomenological Analysis (IPA). Results: Five superordinate themes emerged: I didn't want, I didn't see and I didn't feel; Adolescence? I suddenly became a mother; History repeats itself again and again; Confused Spaces and How difficult is coming into the world? Conclusion: Adolescent mothers, who themselves are daughters of teen mothers, seem to have difficulty in representing the meanings associated with their experience of pregnancy and motherhood. A lack of narrative transmission of the experience of pregnancy from mothers to daughters emerged. The implications for research and social policies will be discussed

Efficacy and adverse events profile of videolaryngoscopy in critically ill patients: subanalysis of the INTUBE study

Background: Tracheal intubation is a high-risk procedure in the critically ill, with increased intubation failure rates and a high risk of other adverse events. Videolaryngoscopy might improve intubation outcomes in this population, but evidence remains conflicting, and its impact on adverse event rates is debated.Methods: This is a subanalysis of a large international prospective cohort of critically ill patients (INTUBE Study) performed from 1 October 2018 to 31 July 2019 and involving 197 sites from 29 countries across five continents. Our primary aim was to determine the first-pass intubation success rates of videolaryngoscopy. Secondary aims were characterising (a) videolaryngoscopy use in the critically ill patient population and (b) the incidence of severe adverse effects compared with direct laryngoscopy.Results: Of 2916 patients, videolaryngoscopy was used in 500 patients (17.2%) and direct laryngoscopy in 2416 (82.8%). First-pass intubation success was higher with videolaryngoscopy compared with direct laryngoscopy (84% vs 79%, P1/40.02). Patients undergoing videolaryngoscopy had a higher frequency of difficult airway predictors (60% vs 40%, P<0.001). In adjusted analyses, videolaryngoscopy increased the probability of first-pass intubation success, with an OR of 1.40 (95% confidence interval [CI] 1.05-1.87). Videolaryngoscopy was not significantly associated with risk of major adverse events (odds ratio 1.24, 95% CI 0.95-1.62) or cardiovascular events (odds ratio 0.78, 95% CI 0.60-1.02).Conclusions: In critically ill patients, videolaryngoscopy was associated with higher first-pass intubation success rates, despite being used in a population at higher risk of difficult airway management. Videolaryngoscopy was not associated with overall risk of major adverse events