Causes and risk factors of urinary incontinence: Avicenna's point of view vs. contemporary findings

Purpose: To extract the causes and risk factors of urinary incontinence from an old medical text by Avicenna entitled "Canon of Medicine" and comparing it with contemporary studies. Materials and Methods: In this study, etiology and risk factors of urinary incontinence were extracted from Avicenna's "Canon of Medicine". Commentaries written on this book and other old reliable medical texts about bladder and its diseases were also studied. Then the achieved information was compared with contemporary findings of published articles. Results: Urinary incontinence results from bladder dysfunction in reservoir phase. Bladder's involuntary muscles and voluntary external sphincter are two main components which are involved in this process. Urinary incontinence can exist without obvious structural and neuronal etiologies. According to Avicenna, distemperment of muscular tissue of bladder and external sphincter is the cause for urinary incontinence in such cases. Distemperment is the result of bothering qualities in tissue, i.e.: "wet" and "cold". They are the two bothering qualities which are caused by extracorporeal and intracorporeal factors. Interestingly, the positive associations of some of these factors with urinary incontinence have been shown in recent researches. Conclusion: "Cold" and "wet" distemperment of bladder and external sphincter can be independent etiologies of urinary incontinence which should be investigated

Trans- Obturator Tape (TOT) efficacy in management of stress urinary incontinence and the impact on quality of life: A study in 54 patients

Background: Stress urinary incontinence is a major confounding factor which impairs health quality in women. Some procedures cannot resolve it's impact on life quality. This study aims to assess a less common and newly method; use of transobturator tension- free vaginal tapes (TOT) in regard to short- term and long-term morbidity and impact on patient's quality of life (QOL). Methods: Fifty four patients diagnosed with urinary stress incontinence, underwent a transobturator tension free vaginal tape procedure with or whitout prolapse surgery. Pre and post operative quality of life assessed with Incontinence- specific Quality of Life questionnaire (I-QOL), and objective and subjective cure rate according to patients signs and symptoms before operation, early and late surgical complications like hemorrhage, Injury and/ or perforation of bladder, intestine, urethra and infection were mentioned. Results: The overall intraoperative and early post-operative complication rates were 5.5 and 3.7, respectively. No case of hematoma, bladder or bowel injury was seen. I-QOL scores were significantly higher after surgery. The mean I-QOL score were 23.6 and 64 before and after surgery respectively (p<0.0001). This improvement was independent of the concomitant pelvic floor repair surgery, menopause, underlying diseases, number of parity, body mass index (BMI) and age. The global rate of objective cure was 94.4 (p<0.0001). The majority of women were satisfied with the outcome. (subjective cure was 90.7- p<0.001). Conclusions: This study demonstrates that the TOT approach in the treatment of stress urinary incontinence is a safe and effective procedure which promotes health quality of life

The effectiveness of anger management’s training on difficulty of adolescent's emotion regulation

The purpose of this research is the effect of anger management training on adolescents' emotional regulation. The statistical population is all teenage girls in high school’s 2nd grade in Asemanabad town in academic year of 2015-2016. We used random sampling to select 30 of them as research’s sample which gathered the highest score from questionnaire. The research tool is Gratz and Roemer’s difficulties in emotion regulation scale (DERS).Before interventions, a pre-test had been conducted on both groups. After, training sessions had been conducted for trial group in 8 one hour long periods. Post-test was conducted on both groups after the end of sessions. We used covariance for data analysis. The results confirm the effectiveness of anger management training on difficulty of emotion regulation. Anger is of the most fervent emotions which can impose a lot of damages on mental and physical health.Keywords: Anger management, Difficulty in emotion regulation, Adolescen

Molecular detection of anaplasma marginale and Anaplasma ovis (Rickettsiales: Anaplasmataceae) in ixodid tick species in Iran

The present study was conducted as the first molecular detection of Anaplasma species in tick samples based on the sequencing of major surface proteins 4 (msp4) gene fragments in different parts of Iran. A total of 130 tick specimens were collected from Hormozgan, Lorestan, and Guilan, Iran, within 2015 to 2017. Hyalomma asiaticum, Hyalomma dromedarii, Rhipicephalus sanguineus, and Rhipicephalus (Boophilus) species were identified in different geographical regions. An amplicon of 464-bp msp4 of Anaplasma was amplified using polymerase chain reaction in various tick species. Three sequences, including one Anaplasma marginale from R. (Boophilus) species and two Anaplasma ovis from Rhipicephalus sanguineus, were obtained after sequencing. It is concluded that bovine and ovine anaplasmosis agents are present in tick samples in Iran. The use of the gene families of six major surface proteins for the detection of various Anaplasma species is recommended. © 2020 by Razi Vaccine & Serum Research Institute

Self-similar structure of magnetized ADAFs and CDAFs

(Abridged) We study the effects of a global magnetic field on viscously-rotating and vertically-integrated accretion disks around compact objects using a self-similar treatment. We extend Akizuki & Fukue's work (2006) by discussing a general magnetic field with three components ($r, \phi, z$) in advection-dominated accretion flows (ADAFs). We also investigate the effects of a global magnetic field on flows with convection. For these purposes, we first adopt a simple form of the kinematic viscosity $\nu=\alpha c_{s}^{2}/\Omega_{K}$ to study magnetized ADAFs. Then we consider a more realistic model of the kinematic viscosity $\nu=\alpha c_{s}H$, which makes the infall velocity increase but the sound speed and toroidal velocity decrease. We next use two methods to study magnetized flows with convection, i.e., we take the convective coefficient $\alpha_{c}$ as a free parameter to discuss the effects of convection for simplicity. We establish the $\alpha_{c}-\alpha$ relation for magnetized flows using the mixing-length theory and compare this relation with the non-magnetized case. If $\alpha_{c}$ is set as a free parameter, then $|v_{r}|$ and $c_{s}$ increase for a large toroidal magnetic field, while $|v_{r}|$ decreases but $|v_{\phi}|$ increases (or decreases) for a strong and dominated radial (or vertical) magnetic field with increasing $\alpha_{c}$. In addition, the magnetic field makes the $\alpha_{c}-\alpha$ relation be distinct from that of non-magnetized flows, and allows the $\rho\propto r^{-1}$ or $\rho\propto r^{-2}$ structure for magnetized non-accreting convection-dominated accretion flows with $\alpha+g\alpha_{c}< 0$ (where $g$ is the parameter to determine the condition of convective angular momentum transport).Comment: 22 pages, 5 figures, Accepted for publication in MNRA

Transplacental transmission of SARS-CoV-2 infection: A case report from Iran

We report a case of SARS-CoV-2 vertical transmission through the placenta in a neonate whose mother had non-M3 acute myeloid leukemia (AML) that was complicated with Covid-19 in the last trimester. Viral load in nasopharyngeal swabs from mother and neonate were high. Real-time PCR of the fetal side of the placenta was positive for SARS-CoV-2, which makes it possible to consider this case as a congenital case of SARS-CoV-2 infection that is transmitted through vertical transmission. © 2020, Author(s)