Classification of the Primary Sources of Children's Literature in Greek in the Decade 1995-2005, with the Assistance of Data Analysis Methods.

This paper attempts to chart the landscape in literature for children and young people by examining data such as subject matter, first-person and third-person narration, characters (gender, age), year of initial publication, re-issues, gender of author, age of author at initial publication, place of issue, illustration, originality and parody (adaptations). Based on the data collected, this paper proposes a classification for the body of Greek literature for children and young people that is being investigated

Comprehension of Literary Texts by Elementary School Pupils in Greece

This paper attempts to record the popularity of recreational reading among pupils, focusing on their understanding of the text. Initially we explore the factors, i.e. family and school, that influence pupils’ reading habits. Then, using the questionnaire method, we investigate what a reader-pupil in the last two years of elementary school in Greece understands after having read a literary text, with respect to the fictional characters, setting, plot, viewpoint/narration and style

The Views of Greek Primary School Teachers about Children’s Literature

This study investigates the views of Greek primary education teachers regarding children’s literature, their contribution to fostering their pupils’ love of reading, and the help they provide their pupils in understanding texts. We investigate what teachers believe children’s/young adults’ literature to be, how many are interested in it and how many attempt to transmit their love of reading to their students. These attitudes are investigated in correlation to the teachers’ education, age, social features, gender and years of teaching experience. In addition, teachers’ perceptions of their students’ opinions of children’s literature are explored and the degree to which they believe the students to be interested in it. Finally, this research also attempts to chart teachers’ reading preferences

Polymorphism FXII 46C>T and cardiovascular risk: additional data from Spanish and Tunisian patients

<p>Abstract</p> <p>Background</p> <p>Previous studies showed an association between Coagulation Factor XII 46C>T polymorphism and variation in FXII plasma levels, as 46C>T seems to affect the translation efficiency. Case-control studies in Spanish samples indicated that genotype T/T is an independent risk factor for venous thrombosis, ischemic stroke and acute coronary artery disease. In this study, we tried to reaffirm the importance of 46C>T in two samples from Spain and Tunisia.</p> <p>Findings</p> <p>A Transmission Disequilibrium Test (TDT) based on 101 family trios from Barcelona with one offspring affected by ischemic heart disease and a classical case-control study based on 76 patients with IHD and 118 healthy individuals from North and Centre-South Tunisia were conducted. Subjects were genotyped for 46C>T and data were analyzed accordingly, revealing no association in any of the two samples (TDT: P = 0.16, relative risk 1.17; case-control study: P = 0.59, odds ratio 1.36).</p> <p>Conclusion</p> <p>The results suggest that 46C>T is not a risk factor for ischemic heart disease in any of the two analyzed samples and therefore the polymorphism seems not to be a universal risk factor for cardiovascular diseases.</p

The Mediterranean Sea as a barrier to gene flow: evidence from variation in and around the F7 and F12 genomic regions

<p>Abstract</p> <p>Background</p> <p>The Mediterranean has a long history of interactions among different peoples. In this study, we investigate the genetic relationships among thirteen population samples from the broader Mediterranean region together with three other groups from the Ivory Coast and Bolivia with a particular focus on the genetic structure between North Africa and South Europe. Analyses were carried out on a diverse set of neutral and functional polymorphisms located in and around the coagulation factor VII and XII genomic regions (F7 and F12).</p> <p>Results</p> <p>Principal component analysis revealed a significant clustering of the Mediterranean samples into North African and South European groups consistent with the results from the hierarchical AMOVA, which showed a low but significant differentiation between groups from the two shores. For the same range of geographic distances, populations from each side of the Mediterranean were found to differ genetically more than populations within the same side. To further investigate this differentiation, we carried out haplotype analyses, which provided partial evidence that sub-Saharan gene flow was higher towards North Africa than South Europe.</p> <p>Conclusions</p> <p>As there is no consensus between the two genomic regions regarding gene flow through the Sahara, it is hard to reach a solid conclusion about its role in the differentiation between the two Mediterranean shores and more data are necessary to reach a definite conclusion. However our data suggest that the Mediterranean Sea was at least partially a barrier to gene flow between the two shores.</p

Evaluating Digital Tools for Sustainable Agriculture using Causal Inference

In contrast to the rapid digitalization of several industries, agriculture suffers from low adoption of climate-smart farming tools. Even though AI-driven digital agriculture can offer high-performing predictive functionalities, it lacks tangible quantitative evidence on its benefits to the farmers. Field experiments can derive such evidence, but are often costly and time consuming. To this end, we propose an observational causal inference framework for the empirical evaluation of the impact of digital tools on target farm performance indicators. This way, we can increase farmers' trust by enhancing the transparency of the digital agriculture market, and in turn accelerate the adoption of technologies that aim to increase productivity and secure a sustainable and resilient agriculture against a changing climate. As a case study, we perform an empirical evaluation of a recommendation system for optimal cotton sowing, which was used by a farmers' cooperative during the growing season of 2021. We leverage agricultural knowledge to develop a causal graph of the farm system, we use the back-door criterion to identify the impact of recommendations on the yield and subsequently estimate it using several methods on observational data. The results show that a field sown according to our recommendations enjoyed a significant increase in yield (12% to 17%).Comment: Accepted for publication and spotlight presentation at Tackling Climate Change with Machine Learning: workshop at NeurIPS 202

Genetic Contribution of Femoral Neck Bone Geometry to the Risk of Developing Osteoporosis : A Family-Based Study

Femoral neck geometry parameters are believed to be as good as bone mineral density as independent factors in predicting hip fracture risk. This study was conducted to analyze the roles of genetic and environmental factors in femoral properties measured in a sample of Spanish families with osteoporotic fractures and extended genealogy. The "Genetic Analysis of Osteoporosis (GAO) Project" involved 11 extended families with a total number of 376 individuals. We studied three categorical phenotypes of particular clinical interest and we used a Hip structural analysis based on DXA to analyze 17 strength and geometrical phenotypes of the hip. All the femoral properties had highly significant heritability, ranging from 0.252 to 0.586. The most significant correlations were observed at the genetic level (ρ). Osteoporotic fracture status (Affected 2) and, particularly, low bone mass and osteoporotic condition (Affected 3) had the highest number of significant genetic correlations with diverse femoral properties. In conclusion, our findings suggest that a relatively simple and easy to use method based on DXA studies can provide useful data on properties of the Hip in clinical practice. Furthermore, our results provide a strong motivation for further studies in order to improve the understanding of the pathophysiological mechanism underlying bone architecture and the genetics of osteoporosis

Genetic Contribution of Femoral Neck Bone Geometry to the Risk of Developing Osteoporosis : A Family-Based Study

Femoral neck geometry parameters are believed to be as good as bone mineral density as independent factors in predicting hip fracture risk. This study was conducted to analyze the roles of genetic and environmental factors in femoral properties measured in a sample of Spanish families with osteoporotic fractures and extended genealogy. The "Genetic Analysis of Osteoporosis (GAO) Project" involved 11 extended families with a total number of 376 individuals. We studied three categorical phenotypes of particular clinical interest and we used a Hip structural analysis based on DXA to analyze 17 strength and geometrical phenotypes of the hip. All the femoral properties had highly significant heritability, ranging from 0.252 to 0.586. The most significant correlations were observed at the genetic level (ρ). Osteoporotic fracture status (Affected 2) and, particularly, low bone mass and osteoporotic condition (Affected 3) had the highest number of significant genetic correlations with diverse femoral properties. In conclusion, our findings suggest that a relatively simple and easy to use method based on DXA studies can provide useful data on properties of the Hip in clinical practice. Furthermore, our results provide a strong motivation for further studies in order to improve the understanding of the pathophysiological mechanism underlying bone architecture and the genetics of osteoporosis

Nationwide Genomic Study in Denmark Reveals Remarkable Population Homogeneity

Denmark has played a substantial role in the history of Northern Europe. Through a nationwide scientific outreach initiative, we collected genetic and anthropometrical data from ∼800 high school students and used them to elucidate the genetic makeup of the Danish population, as well as to assess polygenic predictions of phenotypic traits in adolescents. We observed remarkable homogeneity across different geographic regions, although we could still detect weak signals of genetic structure reflecting the history of the country. Denmark presented genomic affinity with primarily neighboring countries with overall resemblance of decreasing weight from Britain, Sweden, Norway, Germany, and France. A Polish admixture signal was detected in Zealand and Funen, and our date estimates coincided with historical evidence of Wend settlements in the south of Denmark. We also observed considerably diverse demographic histories among Scandinavian countries, with Denmark having the smallest current effective population size compared to Norway and Sweden. Finally, we found that polygenic prediction of self-reported adolescent height in the population was remarkably accurate (R2 = 0.639 ± 0.015). The high homogeneity of the Danish population could render population structure a lesser concern for the upcoming large-scale gene-mapping studies in the country

Endometrial scratching during hysteroscopy in women undergoing in vitro fertilization: a systematic review and meta-analysis

ObjectiveEndometrial scratching (ES) during hysteroscopy before embryotransfer (ET) remains doubtable on whether it benefits the reproductive outcomes. The optimal technique is not clear and repeated implantation failure as a challenging field in in vitro fertilization (IVF) seems to be the springboard for clinicians to test its effectiveness.MethodsMedline, PMC, ScienceDirect, Scopus, CENTRAL, Google Scholar were searched from their inception up to April 2023 for studies to evaluate the effectiveness of adding endometrial scratching during hysteroscopy before ET.ResultsThe initial search yielded 959 references, while 12 eligible studies were included in the analyses, involving 2,213 patients. We found that hysteroscopy and concurrent ES before ET resulted in a statistically significant improvement in clinical pregnancy rate (CPR) [RR = 1.50, (95% CI 1.30–1.74), p &lt; 0.0001] and live birth rate (LBR) [RR = 1.67, (95% CI 1.30–2.15), p &lt; 0.0001] with no statistically significant difference on miscarriage rate [RR = 0.80 (95% CI 0.52–1.22), p = 0.30]ConclusionOur meta-analysis suggests that hysteroscopy with concurrent ES may be offered in IVF before ET as a potentially improving manipulation. Future randomized trials comparing different patient groups would also provide more precise data on that issue, to clarify specific criteria in the selection of patients.Systematic Review RegistrationPROSPERO (CRD42023414117